The UK's COVID-19 epidemic during early 2020 was one of world's largest and unusually well represented by virus genomic sampling. Here we reveal the fine-scale genetic lineage structure of this epidemic through analysis of 50,887 SARS-CoV-2 genomes,...
White House Chief of Staff Mark Meadows seemed to indicate the Trump administration has concluded containment of the virus is not possible.
Tom Inglesby.@WHO: 'The alternative [to working to contain COVID] is to face a “tsunami of cases” that will put the health and lives of health care workers in jeopardy and cripple health care systems, he said. “You run out of capacity to cope.”
Dr Alexandra PhelanLockdowns are not inevitable but an emergency stop. Countries can avoid them with comprehensive test, trace, quarantine, isolate, support systems & public uptake of measures to reduce transmission, inc. masks & distancing.
"Giving up" is never an option.
Helen BranswellDo not give up on trying to control #Covid19, @WHO urges. Lockdowns can be avoided if governments support test, trace & then support people in quarantine and individuals play their part too. The alternative? "A tsunami of cases" that strain health care.
Helen Branswell"If we want to do the best science we can, we need a diverse set of people." — star Yale immunologist @VirusesImmunity talks to @scchak about battling sexism & toxic behavior in academia.
Experts say it’s normal for levels of antibodies to drop after clearing an infection, and that they represent just one arm of the immune response against a virus.
Apoorva MandavilliThe headlines, all of a sudden, are everywhere. UK study showed antibodies to the coronavirus decline so we're all doomed. No immunity, no vaccines, no herd immunity.
People, we have enough real things to worry about. Do not worry about this. 1/x
During the evolution of SARS-CoV-2 in humans a D614G substitution in the spike (S) protein emerged and became the predominant circulating variant (S-614G) of the COVID-19 pandemic. However, whether the increasing prevalence of the S-614G variant...
Marion KoopmansYes, the transmissibility of SARS COV 2 has increased, based on animal work. @EuropeVeo could explain part of the difference between early containment success and current situation
Pathogen genomes provide insights into their evolution and epidemic spread. We sequenced 1,439 SARS-CoV-2 genomes from Switzerland, representing 3-7% of all confirmed cases per week. Using these data, we demonstrate that no one lineage became...
Tanja StadlerInsights into the evolution and epidemiology of SARS-CoV-2 in Switzerland until the end of August based on data from our nation-wide sequencing effort; a time period covering the first wave, low case numbers, and slow exponential growth over the summer medrxiv.org/cgi/content/sh… 1/2
Tests on more than 365,000 people in England have shown that the antibody response to the virus that causes COVID-19 wanes over time.
Helen WardAs we report the latest findings from the REACT studies this week, I’d like to say a huge thank you to the hundred of thousands of people who have taken part. You make a major contribution to research - we couldn’t do this without you!
SARS-CoV-2 has caused a global pandemic with millions infected and numerous fatalities. Questions regarding the robustness, functionality, and longevity of the antibody response to the virus remain unanswered. Here we report that the vast majority...
Background: Two antigen-detecting rapid diagnostic tests (Ag-RDTs) are now approved through the WHO Emergency Use Listing procedure and can be performed at the point-of-care. However, both tests use nasopharyngeal (NP) swab samples. NP swab samples...
Michael MinaNew paper showing strong agreement between nasal (ie self collection) and nasopharyngeal swab on rapid test. This is an important finding since, in US, rapid tests currently authorized for nasopharyngeal swabs and thus need healthcare collections
The country has averaged at least 71,000 new coronavirus cases a day over the past week, the most in any seven-day stretch of the pandemic.
Apoorva MandavilliNEW: New British report says antibody levels to coronavirus are declining, prompting widespread fears. But experts said these worries were overblown: “Some of these headlines are silly."
(Full story coming soon)