Alex Fornito
connectome | brain imaging | complex networks | graph theory | MRI | cognitive neuroscience
Last synced from Twitter 18m ago
The heterogeneous functional architecture of the posteromedial cortex is associated with selective functional connectivity differences in Alzheimer's disease
The posteromedial cortex (PMC) is a key region involved in the development and progression of Alzheimer's disease (AD). Previous studies have demonstrated a heterogenous functional architecture of th...
Achieving stable dynamics in neural circuits
The brain consists of many interconnected networks with time-varying, partially autonomous activity. There are multiple sources of noise and variation yet activity has to eventually converge to a stable, reproducible state (or sequence of states)...
Dynamic core-periphery structure of information sharing networks in entorhinal cortex and hippocampus
Neural computation is associated with the emergence, reconfiguration and dissolution of cell assemblies in the context of varying oscillatory states. Here, we describe the complex spatio-temporal dynamics of cell assemblies through temporal network...
Correlative three-dimensional super-resolution and block-face electron microscopy of whole vitreously frozen cells
Cells need to compartmentalize thousands of distinct proteins, but the nanoscale spatial relationship of many proteins to overall intracellular ultrastructure remains poorly understood. Correlated light and electron microscopy approaches can help....
Development of Microstructural and Morphological Cortical Profiles in the Neonatal Brain
In the perinatal brain, regional cortical architecture and connectivity lay the foundations for functional circuits and emerging behaviour. Interruptions or atypical development during or before this period may therefore have long-lasting...
A cautionary note on the use of SIFT in pathological connectomes
Click on the article title to read more.
Time Series Complexities and Their Relationship to Forecasting Performance
Entropy is a key concept in the characterization of uncertainty for any given signal, and its extensions such as Spectral Entropy and Permutation Entropy. They have been used to measure the complexity of time series. However, these measures are...
Study Confirms Climate Models are Getting Future Warming Projections Right
A new evaluation of global climate models used to project Earth's future global average surface temperature finds that most have been quite accurate.
The cortical wiring scheme of hierarchical information processing
The vast net of fibres within and underneath the cortical mantle is optimised to support the convergence of different levels of brain organisation, specifically through linking cellular and architectural features of different cortical areas to give...
Sean Carroll
SEAN CARROLL OUR PREPOSTEROUS UNIVERSE TICKETS SEAN CARROLL We shouldn’t be here. Not really. It was never likely that one day trillions upon trillions of atoms would all come together and make a sentient little sack of anxiety to wander around the...
Mechanisms of tissue and cell-type specificity in heritable traits and diseases
The pathology of heritable human traits and diseases often affects a narrow range of tissues, even when causal genes are expressed widely across the body. In this Review, Hekselman and Yeger-Lotem discuss the latest understanding of tissue...
Towards an MRI-based mesoscale connectome of the squid brain
Using high-resolution diffusion magnetic resonance imaging (dMRI) and a suite of old
and new staining techniques, the beginnings of a multi-scale connectome map of the
squid brain is erected. The first of its kind for a cephalopod, this includes...
Deputy PM slams 'raving inner city lunatics' for bushfire climate link
Michael McCormack said people in disaster areas “don't need the ravings of some pure, enlightened and woke capital city greenies at this time”.
Thirteen tips for engaging with physicists, as told by a biologist
Working alongside physicists made me a better science communicator, says Ken Kosik, and helped me to clarify knowledge gaps in my own field.
Twelve tips for engaging with biologists, as told by a physicist
The fastest way to become fluent in the language of a new scientific discipline is to embed yourself inside it and use it regularly, says Sarah Bohndiek.