Anirban Maitra
Scientific Director of the Ahmed Center for Pancreatic Cancer Research at MD Anderson Cancer Ctr. Also a GI Pathologist. Tweets & opinions expressed are my own.
Last synced from Twitter 15m ago
'I just got fed up with the sexism. It was everywhere'
BBC News 49h 5 tweets
How Dame Stephanie Shirley went from child refugee to computer industry and women's rights pioneer.
Anirban Maitra Remarkable human being. 13h
'Jeopardy' star James Holzhauer makes donation to local pancreatic cancer walk in Alex Trebek's name
TheHill 16h 1 tweets
James Holzhauer, the recent "Jeopardy" champion who won a headline-making 32 games, made a donation to a local pancreatic cancer walk in the name of host Alex Trebek who is battling the same disease,
Super-resolution imaging reveals the evolution of higher-order chromatin folding in early carcinogenesis
bioRxiv 15h 1 tweets
Aberrant chromatin structure is a hallmark in cancer cells and has long been used for clinical diagnosis of cancer. However, underlying higher-order chromatin folding during malignant transformation remains elusive, due to the lack of molecular...
Anirban Maitra The STORM troopers from have a counterintuitive observation in multistep cancer progression from what #pathologists are taught - chromatin “decompaction” & fragmentation as a feature of early neoplasia, possibly promoting genomic instability. 15h
A Tribute to John Mendelsohn: A Pioneer in Targeted Cancer Therapy
Cancer Research 18h 1 tweets
Cancer scientists and clinicians are mourning the death of one of the most accomplished members of their community: Dr. John Mendelsohn. He was a pioneer in targeted cancer therapy and was instrumental for the discovery and deployment of the first...
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Anirban Maitra A tribute to the late John Mendelsohn from his former mentees in today’s 18h
Dogs And The Early Detection of Cancer | Dr. Len's Blog
Blogs.cancer.org 379d 2 tweets
Cancer Screening, Dogs Detect Cancer: BioScent DX, Inc.
Cancer Screening, Dogs Detect Cancer: BioScent DX, Inc. 32h 1 tweets
BioScent DX is using the scent capabilities of dogs to provide highly accurate, low cost, non-invasive screening for cancer.
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Anirban Maitra The dog days of cancer screening are upon us. BioScentDx is offering DTC periodic screening for various solid tumors based on breath analysis by canines. Recent paper that leaves MUCH to be desired. Who regulates these products? 32h
Accuracy of Canine Scent Detection of Non–Small Cell Lung Cancer in Blood Serum | The Journal of the American Osteopathic Association
Jaoa.org 32h 1 tweets
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Anirban Maitra The dog days of cancer screening are upon us. BioScentDx is offering DTC periodic screening for various solid tumors based on breath analysis by canines. Recent paper that leaves MUCH to be desired. Who regulates these products? 32h
Preclinical Modelling of PDA: Is Organoid the New Black?
MDPI 35h 1 tweets
Pancreatic ductal adenocarcinoma (PDA) is a malignancy of the exocrine pancreas with the worst prognosis among all solid tumours, and soon to become the second leading cause of cancer-related deaths. A more comprehensive understanding of the...
Anirban Maitra Hats off to crew for channeling their #OITNB fandom in this #PancreaticCancer review. 👏🏽👏🏽 35h
Quantitative evidence for early metastatic seeding in colorectal cancer
Nature Genetics 44h 6 tweets
Analysis of evolutionary dynamics of colorectal cancers and paired distant brain or liver metastases provides evidence that early disseminated cancer cells seed metastases before the carcinoma is clinically detectable.
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Anirban Maitra I always thought early dissemination in subclinical disease was a feature peculiar to #PancreaticCancer but in this paper, elegantly uses patient specific modeling to show that most #colorectal cancers demonstrate this as well. 43h
Evaluation of Commercial Circulating Tumor DNA Test in Metastatic Prostate Cancer
JCO Precision Oncology 7d 1 tweets
PURPOSE Circulating tumor DNA (ctDNA) sequencing provides a minimally invasive method for tumor molecular stratification. Commercial ctDNA sequencing is increasingly used in the clinic, but its accuracy in metastatic prostate cancer is untested. We...
Articles in Press - Clinical Gastroenterology and Hepatology
Cghjournal.org 47h 1 tweets
Anirban Maitra Racial disparities & trends in #PancreaticCancer incidence and mortality. While the disparities have gotten marginally better, African Americans continue to have higher incidence & mortality across all stages of disease. 47h
Oncotarget | A composite polymer nanoparticle overcomes multidrug resistance and ameliorates doxorubicin-associated cardiomyopathy
Oncotarget.com 3d 1 tweets
Anirban Maitra My father & I collaborated on several nanotechnology projects. Our last paper was published after he passed away & is dedicated to him. Ironically, the very last conversation I had with him was about the figures for this paper. Make sure to call dad! 3d
Truth: A Love Story
Harvard Magazine 5d 19 tweets
A scientist discovers his own family’s secrets.
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Anirban Maitra I am blown away by this odyssey of discovery and reconciliation authored by the great I hope you enjoy this weekend must read as much as I did. 4d
Declining Patient Engagement at ASCO 2019
Audun Utengen - Symplur 12d 1 tweets
    Analyze the Data in Symplur Signals 2019 2018 2017 2016 2015
Trends in mortality due to cancer in the US by age and county-level income, 1999-2015
OUP Academic 5d 3 tweets
Abstract. Disparities in cancer mortality by county-level income have increased. It is unclear whether these widening disparities have affected older and young
Anirban Maitra Cancer mortality rates by age and county level income quintile. Paper from in Disparities in cancer mortality are rising but especially in the under 65 age group (for eg see curves separating in #PancreaticCancer) #ACA 5d
Fecal Transplant Is Linked to a Patient’s Death, the F.D.A. Warns
Denise Grady - Nytimes.com 5d 19 tweets
The agency said two patients received donated stool that had not been screened for drug-resistant germs, leading it to halt clinical trials until researchers prove proper testing procedures are in place.
Anirban Maitra This feels a lot like the early days of CAR T cells. The contributions of patients who bravely consent to facing the unknown through early phase #clinicaltrials should never be diminished, when all is said and done (and yes, this too shall pass). 5d
Special fibroblasts help pancreatic cancer cells evade immune detection
Cold Spring Harbor Laboratory 6d 2 tweets
Cold Spring Harbor, NY — Pancreatic ductal adenocarcinoma (PDAC) is the fourth leading cause of cancer-related deaths in the world. Mostly chemoresistant, PDAC so far has no effective treatment. Understanding the connective tissue, called stroma,...
Anirban Maitra Press release on the #PancreaticCancer paper via 6d
Loss of ARID1A in tumor cells renders selective vulnerability to combined ionizing radiation and PARP inhibitor therapy
Clinical Cancer Research 6d 1 tweets
Purpose: Somatic inactivating mutations in ARID1A, a component of the SWI/SNF chromatin remodeling complex, are detected in various types of human malignancies. Loss of ARID1A compromises DNA damage repairs, and induced DNA damage burdens may...
Anirban Maitra Preclinical study in from team in ARID1A deficient #OvarianCancer shows the possibility of exploiting defective NHEJ in these cells for combination with PARPinh. Cc: 6d
Detection of NTRK Fusions: Merits and Limitations of Current Diagnostic Platforms
Cancer Research 6d 1 tweets
Oncogenic fusions involving NTRK1, NTRK2 , and NTRK3 with various partners are diagnostic of infantile fibrosarcoma and secretory carcinoma yet also occur in lower frequencies across many types of malignancies. Recently, targeted small molecular...
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Anirban Maitra All the ways one can diagnose TRK fusions in clinical grade specimens. Review in by et al Very helpful for molecular #pathologists who are increasingly fielding the question of cost effective TRK fusion screening. 6d
Time to End the Manel Tradition
National Institutes of Health (NIH) 7d 37 tweets
NIH director will no longer participate in all-male panels.