DNA: Disease, Nature, Ancestry ─ Three billion letters of you
Inaugural lecture of Chris Ponting, Professor of Medical Bioinformatics
You’ve come a long way over the last 3.5 billion years or so. Well, not you precisely, but your DNA – your genome –...
Robertson et al. report that age-related clonal haemopoiesis (ARCH) is associated
with overall accelerated ageing as measured by epigenetic clocks, which are based
on methylation status. ARCH is driven by somatic mutations in healthy individuals
The recent upswing of microfluidics and combinatorial indexing strategies, further enhanced by very low sequencing costs, have turned single cell sequencing into an empowering technology; analyzing thousands—or even millions—of cells per...
Chris P PontingA comprehensive guide:
12 Grand challenges in single-cell data science
Distinguished chemist who helped to pioneer nuclear magnetic resonance – a new method of analysis
Chris P PontingRex Richards RIP. Two things I remember from only time I met him: (1) He was, as this obituary says, someone wanting to help early career scientists. (2) He was gracious even when I blurted out: "I know a building named after you..."
Archive institutionnelle de l'Université de Genève - Institutional Repository of the University of Geneva
Chris P Ponting@lizworthey Fascinating early history of alignments, the single letter code, and phylogenetic inference and early prejudice against computational biologists, such as Margaret Dayhoff, who do ‘‘not do experimental work.’’
Protein Science, the flagship journal of The Protein Society, serves an international forum for publishing original reports on all scientific aspects of protein molecules. The Journal publishes papers by leading scientists from all over the world...