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Fan Wang joins the McGovern Institute - MIT McGovern Institute
The McGovern Institute is pleased to announce that Fan Wang, currently a Professor at Duke University, will be joining its team of investigators in 2021. Wang is well-known for her work on sensory perception, pain, and behavior. She takes a broad,...
Opposing Influence of Top-down and Bottom-up Input on Excitatory Layer 2/3 Neurons in Mouse Primary Visual Cortex
Jordan and Keller use whole cell recordings in mice navigating in virtual reality
to show that neurons only in superficial cortical layers have a special property:
they integrate visual flow and locomotion speed with opposing signs, allowing them
to...
Permeabilization-free en bloc immunohistochemistry for correlative microscopy
A dense reconstruction of neuronal synaptic connectivity typically requires high-resolution 3D electron microscopy (EM) data, but EM data alone lacks functional information about neurons and synapses. One approach to augment structural EM datasets...
HILS Ph.D. Programs Open House
We hope you can join us on October 29th, 5-7 PM. E.S.T to learn more about the 14 Life Sciences Ph. D programs at Harvard.
Agenda:
5 PM, Welcome
5:20 PM, Ph.D. Admission Panel
6 PM, Individual Ph.D. Program Q&A
Please contact...
A Neural Basis for Categorizing Sensory Stimuli to Enhance Decision Accuracy
Hu et al. discover a neural network that suppresses neural signals caused by weak
noxious stimuli while amplifying those caused by intense stimuli, allowing animals
to ignore weak stimuli and escape only from real harms. They also show that this...
Meet a Nose: Harold McGee
James Beard Award-winning author Harold McGee discusses the relationship between cooking and scent in this edition of Meet a Nose.
Intercellular telomere transfer extends T cell lifespan
The common view is that T-lymphocytes activate telomerase, a DNA polymerase that extends telomeres at chromosome ends, to delay senescence. We show that independently of telomerase, T cells elongate telomeres by acquiring telomere vesicles from...
NIH Director's Pioneer Award Program - Award Recipients
The NIH Common Fund was enacted into law by Congress through the 2006 NIH Reform Act to support cross-cutting, trans-NIH programs that require participation by at least two NIH Institutes or Centers (ICs) or would otherwise benefit from strategic...
[Career Navigator Workshop] Applying to Life Science PhD Programs and a Q&A on Harvard PhD Admissions (HMS Admissions Faculty & Dr. Davie Van Vactor - HMS Dept of Cell Biology, Dr. Jason Heustis - HMS Program in Graduate Education)
Part 1: Applying to PhD Programs: Preparing Competitive Applications for Life Sciences Doctoral Programs and What to Expect from Doctoral Training 4:00 PM – 5:10 PM Jason Heustis (Program in Graduate Education) Davie Van Vactor (Professor of Cell...
Human non-olfactory cognition phase-locked with inhalation - PubMed
Olfactory stimulus acquisition is perfectly synchronized with inhalation, which tunes neuronal ensembles for incoming information. Because olfaction is an ancient sensory system that provided a template for brain evolution, we hypothesized that this...
1
Sandeep Robert Datta
@WiringTheBrain @RedmondOConnell Jay Gottfried showed visual task performance is affected by resp. phase (drives theta in mice, entrains a slow rhythm in people); Noam Sobel has similar in visuospatial task, also showing inhalation-related brain state change. bit.ly/2GccDHp bit.ly/30lDFTt
107d
Nasal Respiration Entrains Human Limbic Oscillations and Modulates Cognitive Function
The need to breathe links the mammalian olfactory system inextricably to the respiratory rhythms that draw air through the nose. In rodents and other small animals, slow oscillations of local field potential activity are driven at the rate of...
1
Sandeep Robert Datta
@WiringTheBrain @RedmondOConnell Jay Gottfried showed visual task performance is affected by resp. phase (drives theta in mice, entrains a slow rhythm in people); Noam Sobel has similar in visuospatial task, also showing inhalation-related brain state change. bit.ly/2GccDHp bit.ly/30lDFTt
107d
Representational drift in primary olfactory cortex
Representations of the external world in sensory cortices may define the identity of a stimulus and should therefore vary little over the life of the organism. In the olfactory system the primary olfactory cortex, piriform, is thought to determine...
jbohnslav/deepethogram
Contribute to jbohnslav/deepethogram development by creating an account on GitHub.
DeepEthogram: a machine learning pipeline for supervised behavior classification from raw pixels
Researchers commonly acquire videos of animal behavior and quantify the prevalence of behaviors of interest to study nervous system function, the effects of gene mutations, and the efficacy of pharmacological therapies. This analysis is typically...
Revealing the structure of pharmacobehavioral space through motion sequencing
By analyzing hundreds of mice treated with a library of neuro- and psychoactive drugs, Wiltschko et al. show that Motion Sequencing can effectively discriminate and categorize drug effects and link molecular targets to behavioral syllables.
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Sandeep Robert Datta
What is the diversity of behaviors induced by drugs…and how can machine learning help capture this diversity and identify underlying mechanisms? Check out our latest mapping the structure of pharmacobehavioral space here
116d
Tenure-track Faculty Position at the Rank of Assistant/Associate Professor job with Harvard Medical School | 519028
Blavatnik Institute at HMS invites applications for faculty positions with a specific goal of advancing diversity in scientific research & discovery
Striatal circuits support broadly opponent aspects of action suppression and production
Imbalance between action suppression and production characterizes several basal ganglia (BG) disorders. Relatedly, the direct and indirect pathways of the BG are hypothesized to promote and suppress actions, respectively. Yet striatal direct (dMSNs)...