Dr CJ Houldcroft 🕷️I hope this is free to read... Kate Bingham gives a great summary of the UK planning for COVID vaccination. "Six vaccines... across four different formats: adenoviral vectors, mRNA, adjuvanted proteins, and whole inactivated viral vaccines"
Identifying linked cases of infection is a key part of the public health response to viral infectious disease. Viral genome sequence data is of great value in this task, but requires careful analysis, and may need to be complemented by additional...
In search for a virus as a possible cause of multiple sclerosis thirteen brains from patients with multiple sclerosis and four brains from persons wit…
Dr CJ Houldcroft 🕷️Virology used to be the wild west! I grow my virus in donated primary human skin cells but in this paper, they are growing herpes simplex virus in a frequently-refreshed sheep choroid plexus primary cell line.
The COVID-19 pandemic has motivated many open and collaborative analytical research projects with real-world impact. However, despite their value, such activities are generally overlooked by traditional academic metrics. Science is ultimately...
Abstract. A late-onset syndrome, consisting of muscle weakness, muscle pain, and unaccustomed fatigue, has been reported with increasing frequency among former
Dr CJ Houldcroft 🕷️Viruses can cause long-term post-infectious complications *even after the initial infection has been cleared*. This is not unique to SARS-CoV-2 - post-polio syndrome is associated with extra complications 30-35 years AFTER infection
The figures on this page show the number of confirmed COVID-19 cases each week from Monday 5 October 2020. They also include data from our Pooled (asymptomatic) Screening programme. We have
Dr CJ Houldcroft 🕷️First week of the Cambridge SARS-CoV-2 testing/screening programme: asymptomatic students 0.3% positive, symptomatic staff & students 10% positive.
Dr CJ Houldcroft 🕷️Cambridge Uni SARS-CoV-2 update: asymptomatic cases have tripled and symptomatic cases 4.5x higher than last week...
Dr CJ Houldcroft 🕷️Asymptomatic and symptomatic case numbers sitting steady this week in Cambridge - taking the growth out of COVID spread is v important step one, getting the numbers down is step two!
Influenza-like illness (ILI) accounts for a large burden of annual morbidity and mortality worldwide. A finer-grained knowledge of the parameters and dynamics of the viruses commonly underlying ILI is needed for modeling, diagnostic, and...
Host IFNL4 haplotype status contributes to the development of chronic hepatitis C virus (HCV) infection in individuals who are acutely infected with the virus. In silico studies revealed that specific amino acid variants at multiple sites on the HCV...
The news comes during the first week of the University’s screening programme
Dr CJ Houldcroft 🕷️Very curious to see what effect the highly structured college system in Cambridge has on student case number and transmission dynamics: varsity.co.uk/news/19975
It would of course be useful to have an *official* university case number dashboard...
As a first-generation immigrant, my mum’s greatest ambition for me was to get into Oxbridge. For her, it was clear that these world-leading universities would be a passport into a better world. So she’ll be aghast to learn of BBC Director General...
National influenza and COVID-19 report, monitoring COVID-19 activity, seasonal flu and other seasonal respiratory illnesses.
Dr CJ Houldcroft 🕷️Another week in which rhinovirus is causing the lion's share of the snotty colds among children (and over a quarter of upper resp tract infections in adults appear to be rhinovirus too).
Plasmodium vivax gene regulation remains difficult to study due to the lack of a robust in vitro culture method, low parasite densities in peripheral circulation and asynchronous parasite development. We adapted an RNA-seq protocol “DAFT-seq” to...