Jibran Khokhar
Neuropsychopharmacologist; co-occurring addiction/mental illness @queensu/@UofT/@Dartmouth Assist. Professor @UofG @OntVetCollege. PI @JKhokharLab
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Common functional networks in the mouse brain revealed by multi-centre resting-state fMRI analysis
Preclinical applications of resting-state functional magnetic resonance imaging (rsfMRI) offer the possibility to non-invasively probe whole-brain net…
Power Causes Brain Damage
Over time, leaders lose mental capacities—most notably for reading other people—that were essential to their rise.
Epigenetic regulation of hippocampal FosB expression controls behavioral responses to cocaine
Drug addiction results in part from maladaptive learning, including the formation of strong associations between the drug and the circumstances of consumption. However, drug-induced changes in gene expression underlying the saliency of these...
Dual and Opposing Functions of the Central Amygdala in the Modulation of Pain. - PubMed - NCBI
PubMed comprises more than 30 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Short- and long-access palatable food self-administration results in different phenotypes of binge-type eating
Binge eating disorder (BED), the most common eating disorder in the United States, is characterized by binge-type eating and is associated with higher…
Association of Neurocognitive and Physical Function With Gait Speed in Midlife
This 5-decade cohort study of a New Zealand population examines whether slow gait speed in middle age is associated with accelerated biological aging, as well as poor neurocognitive functioning in childhood and cognitive decline from childhood to...
'We'll make you bleed': Queen's University investigating racist and homophobic note posted inside dorm | CBC News
Queen's University is investigating a racist, homophobic and violent message posted inside a student residence building where some Indigenous students reside.
What Does Vaping Do To Lungs When It Doesn't Kill?
While e-cigarettes are now responsible for hundreds of acute illnesses and several deaths, even general use of e-cigarettes can cause chronic lung issues. Some are switching back to traditional cigarette smoking. Neither option is a good one.
Vaping illnesses may lead to repeat hospitalizations
The illness now has a name: EVALI, an acronym for "e-cigarette or vaping product use associated lung injury."
Vaping Illnesses Keep Climbing Upward, Nearing 1,300
The cause of the outbreak is still unknown, and the only advice health officials can offer so far is to avoid vaping.
RIM1αβ Are Required at the Corticostriatal Synapses for Habit Formation
Control of instrumental actions relies on a dual system of goal-directed and habit strategies ([Liljeholm and O'Doherty, 2012][1]). Goal-directed actions involve anticipation of rewards and are therefore sensitive to changes in the value of the...
Chemogenetic ligands for translational neurotheranostics
Designer Receptors Exclusively Activated by Designer Drugs (DREADDs) are a popular chemogenetic technology for manipulation of neuronal activity in uninstrumented awake animals with potential for precision medicine-based clinical theranostics....
Control of aversion by glycine-gated GluN1/GluN3A NMDA receptors in the adult medial habenula
Glycine is thought to be primarily an inhibitory neurotransmitter. However, it also acts as a coagonist on excitatory N -methyl-D-aspartate (NMDA) receptors. Otsu et al. examined the function of the NMDA receptor subunit combination GluN1/GluN3A in...
Biomarkers in Neuropsychiatry
Biomarkers in Neuropsychiatry is an international, peer-review, rapid-publication and open access journal published by Elsevier. It is dedicated to disseminating original data, systematic reviews and...
Do safe-injection sites work?
International evidence suggests that letting addicts take drugs under supervision saves lives
Vaping illness epidemic shows no sign of slowing
Most patients appear to be young men who reported vaping THC.
Pot Legalization Makes Vaping Deadly
Recent injuries and deaths demonstrate the need for Washington to take control over cannabis policy.