Eric Topol
physician-scientist, author, editor
Thought Leader
#53 Cancer Research
#118 Genetics
#396 The New Center
Last synced from Twitter 6m ago
More Strikeouts Than Hits? Welcome to Baseball’s Latest Crisis
Nytimes.com 43h 2 tweets
This could be the first season in major league history to feature more strikeouts than hits, a slowdown that worries many league officials.
Eric Topol It's taken >> 40 years, but now the strikeouts ≥ hits per team in baseball is beginning to resemble life science research. data , by 2h
Models Will Run the World
WSJ 13h 4 tweets
The software revolution has transformed business. What’s next? Processes that constantly improve themselves without need of human intervention.
Eric Topol 8 years ago, predicted software would eat the world, which happened. Now it's software writing software = models = #AI by 12h
An immune response with a sweet tooth
Nature.com 5d 3 tweets
A previously unknown pathway that enables mammalian cells to recognize infection and trigger an immune response requires a kinase enzyme in the host cell to bind a sugar molecule produced by infecting bacteria.
Eric Topol Like a deep neural network, but in nature. PRRs (pattern-recognition receptors), PAMPs (pathogen-associated molecular patterns) and our immune system activation to a bacterial infection. A newly recognized pathway. #OA 17h
Her Searing Gut Pain Suggested Celiac. Why Didn’t Cutting Out Gluten Help?
Nytimes.com 50h 6 tweets
The patient, a retired nurse, had no insurance and diagnosed herself — which may have been part of the problem.
Eric Topol There are over 12 million serious misdiagnoses a year in the US. Here's one of them. by A disease discovered by a great pathologist (as in this patient), and 1st dean of my alma mater med school 24h
George Whipple - Wikipedia
En.wikipedia.org 24h 1 tweets
Eric Topol There are over 12 million serious misdiagnoses a year in the US. Here's one of them. by A disease discovered by a great pathologist (as in this patient), and 1st dean of my alma mater med school 24h
Should You Get That Scan? Your Doctor Might Not Be Great At Helping You Decide
NPR.org 50h 5 tweets
In a new study, researchers found that doctors are better at explaining the benefits of a common cancer screening that its potential downsides. But overtesting comes with risks and costs of its own.
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Eric Topol "Is healthcare structured to give patients the information they need to make informed decisions?"— —No. Besides the points here, patients aren't given the information on radiation exposure (mSv or CXR equivalents). 43h
Why Is Homo Sapiens the Sole Surviving Member of the Human Family?
Kate Wong - Scientific American 5d 3 tweets
Recent fossil, archaeological and genetic discoveries are revising the rise of our species
Eric Topol Ever wonder why Homo sapiens survived but the other humans didn't? adroitly reviews the backstory and evidence. w/ 44h
All My Tweets - View all your tweets on one page.
Allmytweets.net 100d 2 tweets
View all tweets from any Twitter user on one page. Fast, Free and Easy. Great for viewing, searching and archiving old tweets.
Eric Topol One of main reasons I like is that for all the articles I post (X 9 yrs) I can archive and search via #MyTwitterEpiphany 45h
Three Science Experiments You Can Do With Your Phone
WIRED 4d 3 tweets
Your phone can measure acceleration, magnetic field, sound, location, and maybe more—which turns it into a portable data collector for science projects.
‘Lamarck’s Revenge’ Review: Inheriting the Wrong Ideas
WSJ 46h 3 tweets
Epigenetic changes explain, in part, why even identical twins can differ from each other.
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Eric Topol "Perhaps no other term (#epigenetics) inspires so much debate among scientists about how to define it" The revenge of' Lamarck's Revenge', love this review by 46h
The Fatal Flaws of Food Frequency Questionnaires and Other Memory-Based Dietary Assessment Methods
Journal of Clinical Epidemiology 3d 7 tweets
There is an escalating debate over the value and validity of memory-based dietary assessment methods (M-BMs). Proponents argue that despite limitations, M-BMs such as food frequency questionnaires (FFQs), provide valid and valuable information...
Eric Topol As in almost all diet studies, data collection relies on participant memory. A new paper assails this methodology as "Fatal Flaws" via 3d
Finding useful biomarkers for Parkinson’s disease
Science Translational Medicine 5d 3 tweets
The recent advent of an “ecosystem” of shared biofluid sample biorepositories and data sets will focus biomarker efforts in Parkinson’s disease, boosting the therapeutic development pipeline and enabling translation with real-world impact.
Eric Topol For #Parkinsons disease, good to see all these groups sharing data, collaborating in search of biomarkers and better approaches 3d
Late to the Driverless Revolution
WSJ 3d 10 tweets
America’s car industry dismissed the potential of autonomous driving for years as tech companies plunged ahead. Now Detroit is racing to catch up.
Eric Topol When tech titans override the incumbents: the self-driving car story here, which is going to repeat in #healthcare the Saturday essay 3d
Dorothea Lange's lens on humanity
The Lancet 3d 4 tweets
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Eric Topol "The pictures touched our humanity. Facts matter, but images move us." From Sir 's description of Dorothea Lange's lens on humanity exhibit 3d
Gut Feeling: To Stay Healthy, Keep Your Body’s Microbes in Line
Jo Craven McGinty - WSJ 3d 3 tweets
If the mix of microbes in your body gets out of whack, the same organisms that ensure our health can make us sick.
Eric Topol No question our gut #microbiome is key for health, diseases by But where are the data to back these ads "to benefit everybody" and all the rest of pre- , pro-, and post-biotics? 3d
Dietary carbohydrate intake and mortality: a prospective cohort study and meta-analysis
The Lancet Public Health 4d 28 tweets
Both high and low percentages of carbohydrate diets were associated with increased mortality, with minimal risk observed at 50–55% carbohydrate intake. Low carbohydrate dietary patterns favouring animal-derived protein and fat sources, from sources...
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Eric Topol Carbohydrates in the diet & death: both high & low CHO are not good (U-shape curve); but what is good = plant, not animal, sources 15,428 people w/ 25-yr follow up + meta-analysis by et al #OA 4d
Quantum-inspired computational imaging
Science 4d 1 tweets
Traditional imaging techniques involve peering down a lens and collecting as much light from the target scene as possible. That requirement can set limits on what can be seen. Altmann et al. review some of the most recent developments in the field...
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Eric Topol Eventually, medical imaging will be revolutionized by quantum computing and #AI, as beautifully reviewed here by But we may have to go thru a winter to get there 4d
The race is on to dominate quantum computing
The Economist 4d 5 tweets
But the technology may face a winter before it enters its summer
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Eric Topol Eventually, medical imaging will be revolutionized by quantum computing and #AI, as beautifully reviewed here by But we may have to go thru a winter to get there 4d
Digesting New Developments in Biosensors | NEJM
New England Journal of Medicine 4d 2 tweets
Clinical Implications of Basic Research from The New England Journal of Medicine — Digesting New Developments in Biosensors
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Eric Topol There's biosensors, and then there's real biosensors bacterium engineered to detect GI bleeding 4d
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Eric Topol So much interest/progress in gene therapy for humans now. But genetic engineering of bacteria is showing potent potential, too. — Metabolic disease — Diagnostic sensor 4d
NYU Offers Full-Tuition Scholarships for All Medical Students
Melissa Korn - WSJ 4d 70 tweets
NYU said it will cover tuition for all its medical students, a first among the nation’s major medical schools and an attempt to expand career options for graduates who won’t be saddled with six-figure debt.
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Eric Topol 2 down, ~144 to go by congrats 1st tuition-free med school a decade ago The med school I'm proud to have started in '04 w/ Floyd (Fred) Loop's full support #meded 4d