Harmit Malik
Study genetic conflicts professionally. Try to avoid conflicts in personal life (with mixed results).
Last synced from Twitter 17m ago
Sacha Baron Cohen Uses ADL Speech to Tear Apart Mark Zuckerberg
Accepting an award from the Anti-Defamation League, the comedian called Facebook “the greatest propaganda machine in history.”
Single-cell transcriptomics of the naked mole-rat reveals unexpected features of mammalian immunity
A single-cell transcriptomic study of the immune system of the cancer-resistant naked mole-rat reveals that this animal lacks natural killer (NK) cells, thought to be crucial for cancer resistance. In contrast to dramatically expanded NK cell...
Mitotic domains reveal early commitment of cells in Drosophila embryos
In embryos of Drosophila melanogaster all the nuclei in the syncytial egg divide with global synchrony during the first 13 mitotic cycles. But with cellularization in the 14th cycle, global mitotic synchrony ceases. Starting about one hour into the...
Mechanisms of Convergent Egg Provisioning in Poison Frogs
Maternal provisioning has evolved multiple times in amphibians, including in South
American and Malagasy poison frogs. Field studies in Ecuador and Madagascar by Fischer,
Roland et al. reveal that maternal care facilitates toxin provisioning and...
Infecting mosquitoes with bacteria led to dramatic drops in dengue in trials
The bacterium doesn’t harm the mosquitoes, but it blocks viruses in them from replicating, vastly reducing the risk they will transmit dengue.
CpG dinucleotides inhibit HIV-1 replication through zinc finger antiviral protein (ZAP)-dependent and -independent mechanisms
CpG dinucleotides are suppressed in the genomes of many vertebrate RNA viruses, including HIV-1. The cellular antiviral protein ZAP binds CpGs and inhibits HIV-1 replication when they are introduced in the viral genome. However, it is not known if...
Ten rules for succeeding in academia through upward toxicity
Universities preach meritocracy but, in reality, bend over backwards to protect toxic personalities, says Irina Dumitrescu
Leishmania RNA virus exacerbates Leishmaniasis by subverting innate immunity via TLR3-mediated NLRP3 inflammasome inhibition
NLRP3 activation by Leishmania parasites is critical to the outcome of the disease. Here the authors show that LRV, a virus infecting Leishmania strains associated with more severe human disease, enables the parasite to suppress the inflammasome by...
A new antibiotic selectively kills Gram-negative pathogens
A new antibiotic selectively kills Gram-negative pathogens
Human chromosome‐specific aneuploidy is influenced by DNA‐dependent centromeric features | The EMBO Journal
Missegregation rates vary among different chromosomes, with biased based on abundance of DNA‐dependent centromeric components rather than centromere length.
Obama Photographer Taunts Donald Trump With Throwback Handwritten Notes Snap — HuffPost
Obama-era White House photographer Pete Souza poked fun at Donald Trump onInstagram by comparing the current president's handwritten notes to those ofhis predecessor.Souza on Thursday shared the now-viral image of Trump's super-sized notes ashe...
Harmit Malik
Obama Photographer Taunts Donald Trump With Throwback Handwritten Notes Snap - HuffPost
29h
Employment — MacArthur Foundation
The John D. and Catherine T. MacArthur Foundation supports creative people, effective institutions, and influential networks building a more just, verdant, and peaceful world. MacArthur is placing a few big bets that truly significant progress is...
Condensin II protein dysfunction impacts mitochondrial respiration and mitochondrial oxidative stress responses
The maintenance of mitochondrial respiratory function and homeostasis is essential to human health. Here, we identify condensin II subunits as novel regulators of mitochondrial respiration and mitochondrial stress responses. Condensin II is present...
Coupled Active Systems Encode an Emergent Hunting Behavior in the Unicellular Predator Lacrymaria olor
Coyle et al. analyze how the swan-necked unicellular predator Lacrymaria olor uses
extreme millisecond morphology dynamics to hunt for prey. The fast and slow mechanical
responses of the cell’s helical cytoskeleton to repeated cycles of compression...
First CRISPR treatment for blood diseases shows early benefits
The encouraging data offer hope that genome editing might one day offer a safe, durable cure for sickle cell disease and beta thalassemia.
How Earnest Research Into Gay Genetics Went Wrong
When a well-intentioned study led to a dubious DNA test for same-sex attraction, it exposed the need for safeguards on research in the age of big genetic data.
Matthew J. Gamble, Ph.D. | Albert Einstein College of Medicine
Harmit Malik
einstein.yu.edu/faculty/11838/… Could not find a Twitter handle for Matt; maybe that’s why he’s so productive? 🤔 Today his talk is focused on recent work linking splicing kinetics and fidelity to transcription elongation rates.
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