JHSPH NCRC
Led by faculty, the Novel #Coronavirus Research Compendium rapidly reviews literature. Sign up for our weekly newsletter
Thought Leader
#299 Infectious Disease
Last synced from Twitter 90d ago
🔥 Your COVID Roundup, Week #26
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JHSPH NCRC Did you read this week's NCRC #COVID19 roundup? Our experts reviewed papers on clusters at a university campus, dogs to sniff out COVID-19, multisystem inflammatory syndrome (MIS) in adults, and more. 91d
Serial interval of SARS-CoV-2 was shortened over time by nonpharmaceutical interventions
Science 145d 2 tweets
In epidemiology, serial intervals are measured from when one infected person starts to show symptoms to when the next person infected becomes symptomatic. For any specific infection, the serial interval is assumed to be a fixed characteristic. Using...
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JHSPH NCRC Summary: This study shows that rapid case isolation can effectively reduce the serial interval. It also highlights that the serial interval is not a fixed interval as is often assumed; using “effective” serial intervals in analyses may improve estimates 95d
🔥 Your COVID Roundup, Week #24
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JHSPH NCRC In this week's roundup we have safety & immunogenicity data for the Moderna SARS-CoV-2 #vaccine in older adults, preliminary data on birth outcomes among infants born to women infected with #SARSCoV2, and evidence of #transmission between humans and minks. 105d
🔥 Your COVID Roundup, Week #23
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JHSPH NCRC In this week's newsletter on the latest #COVID19 research: safety of Ibuprofen and other NSAIDS, effects of contact tracing delays, transmission in childcare facilities, preventing outbreaks in long-term care facilities, and more! 112d
🔥 Your COVID Roundup, Week #22
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JHSPH NCRC This week we reviewed articles on universal screening in a NICU in Italy, a rapid saliva test for #SARSCoV2, #Remdesivir trial results and more: If you aren't getting our newsletter, you're missing out! Sign up here: 119d
🔥 Your COVID Roundup, Week #21
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JHSPH NCRC This week's newsletter covers neurological complications of #COVID19, #SARSCoV2 transmission on long-haul flights, critical care capacity in Africa, and more: If you aren't getting our newsletter, you're missing out! Sign up here: 126d
🔥 Your COVID Roundup, Week #20
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JHSPH NCRC Did you get our newsletter with the lates #COVID19 and #SARSCoV2 reviews today? We covered the Sturgis Motorcycle Rally, overnight camps, continuing ACE inhibitors and ARBs, and more. Read more here 133d
The Contagion Externality of a Superspreading Event: The Sturgis Motorcycle Rally and COVID-19 | NCRC
2019 Novel Coronavirus Research Compendium (NCRC) 137d 3 tweets
This study, which was available as a preprint and thus had not yet been peer reviewed, uses county-level SARS-CoV-2 testing data to show that the Sturgis motorcycle rally likely led to substantial increases in cases in the local community where the...
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JHSPH NCRC Dave et al used #COVID19 case counts to compare the number of cases detected to what might have been expected had the rally not taken place, using a weighted average of regions that had no participants (based on phone location data from July 6-August 31) 133d
🔥 Your COVID Roundup, Week #18
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JHSPH NCRC This week's newsletter covers #ConvalescentPlasma, public transport, #FaceShields, and more! Check it out: . Didn't wake up to NCRC in your inbox? Make sure you subscribe to get the latest #COVID19 expert reviews every Tuesday: 147d
Effect of Convalescent Plasma on Mortality among Hospitalized Patients with COVID-19: Initial Three-Month Experience
medRxiv 167d 29 tweets
Importance: Passive antibody transfer is a longstanding treatment strategy for infectious diseases that involve the respiratory system. In this context, human convalescent plasma has been used to treat coronavirus disease 2019 (COVID-19), but the...
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JHSPH NCRC SUMMARY: This large study of #ConvalescentPlasma suggests that earlier treatment w/higher titer plasma may have modest survival benefit. However, it does not provide convincing evidence of a benefit and highlights the need for randomized controlled studies 154d
Effect of Convalescent Plasma on Mortality among Hospitalized Patients with COVID-19: Initial Three-Month Experience | NCRC
2019 Novel Coronavirus Research Compendium (NCRC) 154d 1 tweets
This study included two analyses, one of 35,322 patients the other of 3,082, who were enrolled in the Expanded Access Program (EAP) for convalescent plasma infusions in the US. The study reported that mortality was lower among those who received...
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JHSPH NCRC We reviewed the first analysis of mortality among patients receiving #ConvalescentPlasma therapy from #COVID19 survivors through the US Expanded Access Program. The effect of #ConvalescentPlasma on #COVID19 mortality has not previously been well described 154d
Comparison of Weighted and Unweighted Population Data to Assess Inequities in Coronavirus Disease 2019 Deaths by Race/Ethnicity Reported by the US Centers for Disease Control and Prevention | NCRC
2019 Novel Coronavirus Research Compendium (NCRC) 158d 1 tweets
This study sought to estimate the degree of bias in the CDC-weighted estimates of COVID-19 mortality by race/ethnicity. The CDC approach, motivated to adjust for geographical clustering of COVID-19 deaths in racial/ethnic comparisons,...
JHSPH NCRC Important disparities in #coronavirus deaths by race and ethnicity have been reported in the United States. Below, we summarize our review a "proof of concept" paper that demonstrated bias in the weighted estimates of #COVID19 deaths. 158d
Household transmission of SARS-CoV-2: a systematic review and meta-analysis of secondary attack rate | NCRC
2019 Novel Coronavirus Research Compendium (NCRC) 159d 1 tweets
This meta-analysis was published as a preprint and thus, had not yet undergone peer review. The paper used 40 prior studies to estimate the rate of household secondary transmission for SARS-CoV-2. It estimated a secondary attack rate of 19.0% in...
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JHSPH NCRC Our #epidemiology team worked together to answer a request for main takeaways from as pertains to children and schools. Although this is not advice on what to do, here’s a summary of how this piece relates to some other #COVID19 literature. 159d
Seroprevalence of anti-SARS-CoV-2 IgG antibodies in Geneva, Switzerland (SEROCoV-POP): a population-based study | NCRC
2019 Novel Coronavirus Research Compendium (NCRC) 165d 1 tweets
Overall, 7.9% of individuals in Geneva tested positive for SARS-CoV-2 antibodies in the first 5 weeks of the study. For every confirmed case of COVID-19, there were 11 to 12 estimated additional individuals infected in the community. Importantly,...
JHSPH NCRC Stringhini et al : 2,766 randomly selected persons age 5+ from April 6-May 9, 2020 in Geneva, Switzerland. This study assessed the proportion of people with #SARSCoV2 antibodies on a weekly basis, and so describes time trends. 165d
🔥 Your COVID Roundup, Week #15
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JHSPH NCRC This week's newsletter has a feature on the #COVID19 outbreak at a day camp in Georgia, mitigation efforts in an Italian town, description of the interferon response and other inflammatory markers, #LIPS assay sensitivity, and details on the D614G variant. 168d
Disease and healthcare burden of COVID-19 in the United States | NCRC
2019 Novel Coronavirus Research Compendium (NCRC) 172d 1 tweets
The study estimated the cumulative burden of hospitalization and ICU utilization for COVID-19 across 3142 US counties. It found the 315 counties estimated to be in the 90th percentile of COVID-19 hospitalizations had relatively larger populations...
JHSPH NCRC We reviewed a paper in by Miller et al, which estimated the cumulative burden of #COVID19 in the United States. Keep reading if you're interested in policy implications for resource allocation and planning during the #pandemic. 172d
🔥 Your COVID Roundup, Week #14
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JHSPH NCRC Another week, another newsletter! This one had lots for the #EpiTwitter crowd The link to subscribe to our weekly newsletter is . Our team reviews preprints & published literature about #SARSCoV2 and #COVID19. 174d
🔥 Your COVID Roundup, Week #13
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JHSPH NCRC 📪 It's never too late to sign up for our newsletter! We send out a weekly roundup of #COVID19 #SARSCoV2 literature reviews on Tuesday's. The link to subscribe is . 📰 If you're curious, check out yesterday's edition at 181d
COVID-19 Cases and Deaths in Federal and State Prisons | NCRC
2019 Novel Coronavirus Research Compendium (NCRC) 187d 1 tweets
This study used one of the most robust datasets created through aggregation of publicly available data to investigate the rate of COVID-19 cases and mortality among people currently incarcerated across the United States, including state-level prison...
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JHSPH NCRC #Prison facilities are a key location for #COVID19 outbreaks. A recent study estimated case rate at least 5.5x higher than in the general US population, and death rate was at least 3x higher. The authors acknowledged that true prevalence is likely higher. 187d
SARS-CoV-2 infection in primary schools in northern France: A retrospective cohort study in an area of high transmission | NCRC
2019 Novel Coronavirus Research Compendium (NCRC) 189d 1 tweets
This retrospective cohort study, available as a preprint and thus not yet peer reviewed, examined the infection attack rate from 6 primary schools in Crepy-en-Valois, France among 1340 total participants. They found an attack rate of 8.8% among...
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JHSPH NCRC As districts make decisions about #reopeningschools , we thought it would be timely to do a tweet thread on a recent preprint about #SARSCoV2 infections in primary schools in northern France #EdTwitter #onlineclasses 189d