Jake Dunning
Personal account/views. Infectious diseases consultant & researcher. Emerging and high consequence infections at PHE, Royal Free, UCL, Imperial & Oxford.
Thought Leader
| #287 | Infectious Disease |
Last synced from Twitter 12m ago
How London's top restaurants are skewering the Covid rules
“A table for six? No, sir, that is against the Covid-19 restrictions … unless you promise that your party will discuss business, not pleasure.” Some of London’s fanciest restaurants have discovered a loophole in the tier-2 coronavirus lockdowns...
Jake Dunning
Personal view: whether deliberate or a mistake, this is wrong. Group 'business' lunches cannot be justified in London right now. Loop holes or perceived ambiguities get spotted & exploited, so the opportunity needs to be removed. Avoid unnecessary mixing.
36h
Time to Reassess Tocilizumab’s Role in COVID-19 Pneumonia
In this issue of JAMA Internal Medicine, 3 important articles1-3 explore the use of tocilizumab in coronavirus disease 2019 (COVID-19) pneumonia. Tocilizumab is a humanized monoclonal antibody that binds human interleukin 6 (IL-6) receptors. It is...
Coronavirus (COVID-19) Infection Survey pilot - Office for National Statistics
Estimates for England, Wales and Northern Ireland. This survey is being delivered in partnership with University of Oxford, University of Manchester, Public Health England and Wellcome Trust.
Repurposed antiviral drugs for COVID-19; interim WHO SOLIDARITY trial results
BACKGROUND WHO expert groups recommended mortality trials in hospitalized COVID-19 of four re-purposed antiviral drugs. METHODS Study drugs were Remdesivir, Hydroxychloroquine, Lopinavir (fixed-dose combination with Ritonavir) and Interferon-β1a...
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Jake Dunning
*PRE-PRINT not yet peer reviewed* SOLIDARITY trial findings. What now for remdesivir?
10d
Longitudinal antibody and T cell responses in Ebola virus disease survivors and contacts: an observational cohort study
The continuous high titre of neutralising antibodies and increased T cell response
might support the concept of long-term protective immunity in survivors. The existence
of antibody and T cell responses in contacts of individuals with Ebola virus...
Coronavirus (COVID-19) in the UK
GOV.UK Coronavirus dashboard
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Jake Dunning
A beta version of the new gov.uk #COVID19 data dashboard is now available: coronavirus-staging.data.gov.uk Please don't @ me with any comments or suggestions - there is a feedback button at the top of the page.
13d
Tracking SARS-CoV-2 in Sewage: Evidence of Changes in Virus Variant Predominance during COVID-19 Pandemic
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), responsible for the ongoing coronavirus disease (COVID-19) pandemic, is frequently shed in faeces during infection, and viral RNA has recently been detected in sewage in some countries....
Jake Dunning
More on coronaviruses in sewage, this time from colleagues @NIBSC_MHRA who have longstanding expertise in testing sewage samples (for enteroviruses). Tracking SARS-CoV-2 in Sewage: Evidence of Changes in Virus Variant Predominance during COVID-19 Pandemic
13d
National flu and COVID-19 surveillance reports
National influenza and COVID-19 report, monitoring COVID-19 activity, seasonal flu and other seasonal respiratory illnesses.
2
Jake Dunning
In case you are looking for this week's @PHE_uk #COVID19 weekly surveillance report, it's now been combined with surveillance for influenza and other respiratory viruses. Still the same great COVID-19 content - just with added flu (i.e. all in one place).
16d
Bacteria-fighting cells in the airways boosts infection risk from viruses | Imperial News | Imperial College London
Having more bacteria-fighting immune cells in the nose and throat may explain why some people are more likely to be infected by respiratory viruses.
ISARIC COVID-19 Clinical Data Report: 3 September 2020
ISARIC (International Severe Acute Respiratory and emerging Infections Consortium) partnerships and outbreak preparedness initiatives enabled the rapid launch of standardised clinical data collection on COVID-19 in Jan 2020. Extensive global uptake...
Homepage - GenOMICC COVID-19 Study
Why do some people become seriously ill with COVID-19 while others are hardly affected? Help us find out.
Today - 26/09/2020 - BBC Sounds
Including Sports Desk, Weather and Thought for the Day.
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Jake Dunning
bbc.co.uk/sounds/play/m0… Some great #COVID19 content on @BBCr4today this morning. Stupidly early for a Saturday morning, but thankfully available on BBC Sounds and well worth a listen. 1/4
29d
Coronavirus (COVID-19) Infection Survey pilot - Office for National Statistics
Estimates for England, Wales, and Northern Ireland. This survey is being delivered in partnership with University of Oxford, University of Manchester, Public Health England and Wellcome Trust.
Genetic mechanisms of critical illness in Covid-19
The subset of patients who develop critical illness in Covid-19 have extensive inflammation affecting the lungs and are strikingly different from other patients: immunosuppressive therapy benefits critically-ill patients, but may harm some...
Detection of SARS-CoV-2 within the healthcare environment: a multicentre study conducted during the first wave of the COVID-19 outbreak in England
Understanding how Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is spread within the hospital setting is essential if staff are to be adequately protected, effective infection control measures are to be implemented and nosocomial...
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Jake Dunning
*** PRE-PRINT - NOT YET PEER REVIEWED *** Detection of SARS-CoV-2 within the healthcare environment: a multicentre study conducted during the first wave of the COVID-19 outbreak in England medrxiv.org/content/10.110… pic.twitter.com/E7VJ32vUyH
30d
Joint Biosecurity Centre
The Joint Biosecurity Centre (JBC) provides evidence-based, independent analysis to inform local and national decision-making in response to COVID-19 outbreaks.
How We Survive the Winter
The coming months of the pandemic could be catastrophic. The U.S. still has ways to prepare.