Humans did not evolve from apes, gorillas or chimps. We share a common ancestor and have followed different evolutionary paths.
Simon E. Fisher"Why haven't all primates evolved into humans?" That people come up with such a confused question in the first place suggests we have not been doing a great job in teaching the basics of evolution.
Using language is a skill that allows us to share our ideas and feelings, learn in school and understand the world around us. Unfortunately, using and understanding language is not easy for everyone—especially for people with Developmental Language...
Simon E. FisherRegardless of your age, read this recent article in Frontiers for Young Minds, for an excellent introduction to developmental language disorder (#DLD). Nice work by @larchiba6 & @AlyssaKuiack, helping to raise awareness of this important condition.
Structural brain changes along the lineage that led to modern Homo sapiens have contributed to our unique cognitive and social abilities. However, the evolutionarily relevant molecular variants impacting key aspects of neuroanatomy are largely...
POU3F3, also referred to as Brain-1, is a well-known transcription factor involved
in the development of the central nervous system, but it has not previously been associated
with a neurodevelopmental disorder. Here, we report the identification of...
Simon E. FisherWe describe a neurodevelopmental disorder due to disrupted function of POU3F3, a key regulator of gene activity in the brain. Led by @Lot_SB, our new study identifies rare DNA variants, defines clinical features & tests impact in cellular models. @AJHGNews
The bone, found in a cave, is the oldest modern human fossil ever discovered in Europe. It hints that humans began leaving Africa far earlier than once thought.
Simon E. FisherDeep breath. A skull bone from a cave in southern Greece is reported as oldest Homo sapiens fossil ever discovered in Europe. 4 times older than prior modern human finds on the continent, it dates back a staggering 210k years! @carlzimmer has the lowdown
The Cognomics Conference 2019 is planned for Septermber 4 and 5.
Simon E. FisherAt our exciting Cognomics Conference "Bridging gaps: from genes to cognition", Sept 4-5 in Nijmegen, discover what genomics reveals about human brain structure & function. New deadline + Undergrad/Master student discounts. Register by July 14, last chance: bit.ly/2Ylfb9Fpic.twitter.com/3lXKW4mk9w
Genome sequences from diverse human groups are needed to understand the structure of genetic variation in our species and the history of, and relationships between, different populations. We present 929 high-coverage genome sequences from 54 diverse...
Our research suggests that the theory that conservatives and liberals respond differently to threats isn’t actually true.
Simon E. Fisher"Open science can only happen when journals are willing to publish results that contradict previous findings...We need courage to let beautiful theories die public deaths at the hands of ugly facts." But top journals routinely desk-reject non-replications
How librarians, pirates, and funders are liberating the world’s academic research from paywalls.
Simon E. FisherCompelling article by @B_resnick & @juliaoftoronto with one of the clearest explanations I've ever read of how/why academic publishing is broken & what steps are needed to fix it. Depressing that we as scientists have gone along with this scam for so long
This week (May 20th 2019) has seen yet another splash by an American company offering a polygenic trait score on embryos including intelligence. This is wrong on a number of levels; ethically it is wrong to make this decision as an independent...
Simon E. FisherUsing polygenic trait scores to select human embryos is both unethical & scientifically unsound. Please read this excellent piece by leading genomic scientist @ewanbirney
Decades of early research on the genetics of depression were built on non-existent foundations. How did that happen?
Simon E. Fisher"We're told science self-corrects. The candidate gene literature shows that it often self-corrects very slowly & wastefully, even when the writing has been on the wall for a very long time" @MarcusMunafo to @edyong209 as the SLC6A4 house of cards collapses
If someone says, “I guess it’s in my DNA,” you never hear people say, “DN—what?” We all know what DNA is, or at least think we do. It’s been seven decades since scientists demonstrated that DNA is the molecule of heredity. Since then, a steady...
Simon E. Fisher"Future generations will look back at today as a pivotal moment in DNA’s cultural history" but at the same time public misconceptions about human heredity are rife. Must-read @carlzimmer piece deftly debunking some of the big myths around our genomes
On the 1st of May registration opens for Cognomics Conference 2019: Bridging gaps. This conference will be held on the 4th & 5th of September 2019 at the Max Planck Institute for Psycholinguistics in Nijmegen, The Netherlands.
Simon E. FisherHelp spread the word about our stellar lineup of COGNOMICS 2019 keynote talks, bridging gaps from single-cell genomics to brain structure/function, & from neurodevelopmental disorders to human evolution. Don't miss out, registration closes July 1: