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SHP2 inhibition diminishes KRASG12C cycling and promotes tumor microenvironment remodeling | Journal of Experimental Medicine | Rockefeller University Press
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Rockefeller U. Press
In @JExpMed, Fedele @CarminuzzoF, Neel @DrBenNeel & colleagues find that combining SHP2 and G12C inhibitors abrogates adaptive resistance of KRAS-mutant malignancies, evokes beneficial changes in tumor immune-microenvironment & potentiates PD-1 blockade bit.ly/33H0W4n pic.twitter.com/oShI4KnUw1
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The Nobel Prize in Chemistry 2020
The Nobel Prize in Chemistry 2020 was awarded jointly to Emmanuelle Charpentier and Jennifer A. Doudna "for the development of a method for genome editing".
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Rockefeller U. Press
We join in congratulating Emmanuelle Charpentier and Jennifer A. Doudna for their winning the Nobel Prize in Chemistry 2020 for the development of a method for genome editing. #NobelPrize bit.ly/30YiAPB pic.twitter.com/i57vSam6JK
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Acid reflux drug could help newborn babies recover from brain injury, study suggests
Researchers in China have discovered a potential way to prevent a lack of oxygen or blood flow from causing long-lasting brain damage in newborn children. The study, which will be published September 29 in the Journal of Experimental Medicine (JEM),...
DNA webs may drive lung pathology in severe COVID-19
Sticky webs of DNA released from immune cells known as neutrophils may cause much of the tissue damage associated with severe COVID-19 infections, according to two new studies published September 14 in the Journal of Experimental Medicine (JEM). The...
Unconventional T cells in severe COVID-19 patients could predict disease outcome
Researchers in France have discovered that patients suffering from severe COVID-19 show changes in a class of immune cells known as unconventional T cells. The study, published today in the Journal of Experimental Medicine (JEM), suggests that...
Researchers identify mechanism underlying cancer cells' immune evasion
Researchers in China have discovered how brain cancer cells increase production of a key protein that allows them to evade the body's immune system. The study, which will be published August 27 in the Journal of Experimental Medicine (JEM), suggests...
Researchers develop new mouse model for SARS-CoV-2
Researchers at Yale University School of Medicine have developed a new mouse model to study SARS-CoV-2 infection and disease and to accelerate testing of novel treatments and vaccines against the novel coronavirus. The study, published today in the...
Measuring SARS-CoV-2 neutralizing antibody activity using pseudotyped and chimeric viruses | Journal of Experimental Medicine | Rockefeller University Press
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Rockefeller U. Press
How toothless mock viruses could advance research on #COVID19: In a recent @JExpMed study bit.ly/2DpPfo5, scientists at @RockefellerUniv developed a set of methods to conduct #SARSCoV2 antibody testing without using the real virus. Read more: bit.ly/2DhOEFb pic.twitter.com/yMhbVTpfTf
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How toothless mock viruses could advance research on COVID-19 - News
In more ways than one, antibodies could be the key to alleviating the COVID-19 crisis. Hundreds of labs around the world are studying the antibodies people produce in response to SARS-CoV-2 infection in hopes of developing treatments, predicting...
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Rockefeller U. Press
How toothless mock viruses could advance research on #COVID19: In a recent @JExpMed study bit.ly/2DpPfo5, scientists at @RockefellerUniv developed a set of methods to conduct #SARSCoV2 antibody testing without using the real virus. Read more: bit.ly/2DhOEFb pic.twitter.com/yMhbVTpfTf
170d
Researchers make significant step toward blood test for Alzheimer's disease
Researchers at Washington University School of Medicine in St. Louis have developed a technique to detect minute amounts of a protein fragment linked to Alzheimer's disease in the blood. The study, which will be published July 28 in the Journal of...
OpenAthens | Single sign-on, identity & access management software
Join 2000+ organizations that subscribe to OpenAthens for identity & access management. Seamless single sign-on software to e-resources. Book a demo.
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Rockefeller U. Press
.@OpenAthens is now available for RUP journals! OpenAthens establishes one set of log-in credentials for all web resources and applications. Users log-on once via their home organization to access multiple online services, anytime and anywhere. More info: openathens.org pic.twitter.com/5JS38lRujH
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PSI | IP Registry | IP Intrusion | DDB
PSI offers technology solutions for collaboration in the academic research community
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Rockefeller U. Press
We will be working w/ @ip_registry to improve the process of updating IP addresses used for access authentication. #Librarians can register for free & review info: psiregistry.org #LibraryLife #LibraryTwitter #Libraries #AcademicLibraries #MedLibs pic.twitter.com/ox7gJuRHbx
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Early clinical trial supports tumor cell-based vaccine for mantle cell lymphoma
A phase I/II clinical trial by researchers at Stanford University suggests that vaccines prepared from a patient's own tumor cells may prevent the incurable blood cancer mantle cell lymphoma (MCL) from returning after treatment. The study, which...
Continued nicotine use promotes brain tumors in lung cancer patients, study suggests
Researchers have discovered that nicotine promotes the spread of lung cancer cells into the brain, where they can form deadly metastatic tumors. The study, which will be published June 4 in the Journal of Experimental Medicine, suggests that...
Researchers identify therapeutic targets to prevent cancer-associated muscle loss
Researchers at the University of Nebraska Medical Center have identified a key cell signaling pathway that drives the devastating muscle loss, or cachexia, suffered by many cancer patients. The study, which will be published May 22 in the Journal of...
How herpes simplex virus can evade the immune response to infect the brain
A research team has discovered a molecular mechanism that helps Herpes simplex virus (HSV1) evade the innate immune system and infect the brain causing a rare disease with high mortality. The study from Aarhus University, University of Oxford, and...
Altmetric vs. Dimensions Badges: Understanding the Full Story About Research - Silverchair
This guest blog is written by Cathy Holland, Director, Global Publisher Business Development at Digital Science, a partner in the Silverchair Universe program. Here at Digital Science we are no stranger to Badges. The iconic graphics posted on...
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Rockefeller U. Press
"@altmetric Badges provide a very early & immediate indicator...of what the community is saying about a piece of research, while the Dimensions Badges tell the long-term story of more formal citations" @silverchairnews on the metric badges on our articles
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Gut bacteria can penetrate tumors and aid cancer therapy, study suggests
Researchers at the University of Texas Southwestern Medical Center and University of Chicago have discovered that bacteria that usually live in the gut can accumulate in tumors and improve the effectiveness of immunotherapy in mice. The study, which...
A population of proinflammatory T cells coexpresses αβ and γδ T cell receptors in mice and humans | Journal of Experimental Medicine | Rockefeller University Press
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Rockefeller U. Press
Research in @JExpMed (bit.ly/2VGTUZK) identifies a rare, new cell in the immune system. These cells play a key protective role in immunity to infection but, if unregulated, also mediate tissue damage in #autoimmune disorders. More from @GENbio: bit.ly/3ctOK9J
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Hybrid T Cells May Open Door to Novel Vaccines and Autoimmune Disease Therapies
Researchers at Trinity College Dublin have identified a rare, new 'Jekyll and Hyde' immune cell. The findings should help scientists design more effective vaccines to prevent infections, and may help develop new therapies for autoimmune diseases.
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Rockefeller U. Press
Research in @JExpMed (bit.ly/2VGTUZK) identifies a rare, new cell in the immune system. These cells play a key protective role in immunity to infection but, if unregulated, also mediate tissue damage in #autoimmune disorders. More from @GENbio: bit.ly/3ctOK9J
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