Steve Joffe
Research ethics, pediatric ethics, cancer ethics, genomethics, science policy @ UPenn. Opinions my own. R/Ts ≠ likes.
Last synced from Twitter 10m ago
AstraZeneca unveils massive $750M deal in effort to produce billions of COVID-19 shots
British drugmaker AstraZeneca has made clear its intent to rapidly scale production of Oxford University's COVID-19 vaccine hopeful despite a dearth of clinical data to support its use. Now, with an eye-popping deal worth three-quarters of a billion...
FDA struggles to remain independent amid race for virus cure
Peter Marks's abrupt switch was the latest sign of the FDA's struggle to fend off outside political pressure, particularly from the White House.
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Steve Joffe
A major problem with the (real or perceived) politicization of @US_FDA decision making around Covid is that, even when the agency makes good decisions, the public won't trust them.
8h
Clarinetist Anthony McGill Kneels, Pleads And Plays For Justice
With the help of a few "wrong" notes, the principal clarinetist of the New York Philharmonic turned "America the Beautiful" into a solemn protest of police violence.
Penn Medical Ethics and Health Policy | Penn Medical Ethics & Health Policy Resource for Manuscript Submission
Wondering where to publish your policy paper or editorial?
The Department of Medical Ethics & Health Policy offers this spreadsheet as a resource to our faculty and beyond for guidance on ranking and submission details as you think about...
Lancet retracts major Covid-19 paper that sparked backlash
The journal said the authors of the paper about hydroxychloroquine were unable to complete an independent audit of the data underpinning their analysis.
Could Revisiting US Approval Decisions Become Less Rare?
<span>While not identifying specific situations raising potential questions, the FDA commissioner uses his appearance at agency's annual rare disease event to advise regulatory decisions may be revisited as more data becomes available. </span>
Hahn Defends Using Less ‘Robust’ Data During COVID, But Critics Contend It Has Gone Too Far
<p>US FDA Commissioner Hahn says agency's choice to make fast decisions on less robust data sets during COVID-19, paired with constantly reevaluating these decisions drives best public health outcomes. But critics argue the agency may be pushing the...
Convalescent Plasma Therapy and Clinical Improvement in Severe and Life-threatening COVID-19
This randomized trial compares the effects of convalescent plasma therapy with standard care vs standard care alone on time to clinical improvement among patients with severe or life-threatening COVID-19 disease in China.
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Steve Joffe
This is amazing if you think about how explosive the epidemic in Wuhan was just a couple of months earlier. jamanetwork.com/journals/jama/… pic.twitter.com/MXD2kP0B7O
20h
What Did They Think Would Happen? - The Bulwark
An awful lot of Trump’s defenders in conservative media appear to be shocked by what is happening right now in America. But I’m kind of curious. What did they think was going to happen? The president has a real job. His words have real consequences....
Trump Administration Selects Five Coronavirus Vaccine Candidates as Finalists
The White House is eager to project progress, but the public-private partnership it has created still faces scientific hurdles, internal tensions and questions from Congress.
Governments and WHO changed Covid-19 policy based on suspect data from tiny US company
Surgisphere, whose employees appear to include a sci-fi writer and adult content model, provided database behind Lancet and New England Journal of Medicine hydroxychloroquine studies
Steve Joffe
Has even a single hospital come forward to say that it shares its data with Surgisphere? If so, I haven't seen it.
41h
They’re Working In Healthcare During A Pandemic. They Don’t Get Health Insurance.
“As a nurse or a doctor, at least you're getting paid a decent amount of money to risk your life," one hospital clerical worker earning $15 an hour told BuzzFeed News.
The C.D.C. Waited ‘Its Entire Existence for This Moment.’ What Went Wrong?
The technology was old, the data poor, the bureaucracy slow, the guidance confusing, the administration not in agreement. The coronavirus shook the world’s premier health agency, creating a loss of confidence and hampering the U.S. response to the...
Mayo Clinic patient data fuels AI companies, and consent concerns- STAT
In the past two years, the Mayo Clinic has provided de-identified patient data to 16 digital companies eager to create health AI products and services.
A Moment To Pause - Issue #10
Steve Joffe
Powerful words from a Black man who is a clinician at San Francisco General Hospital. mailchi.mp/2166f1a10e53/a… pic.twitter.com/9CQmwd7PZJ
48h
Before Deliberately Infecting People With Coronavirus, Be Sure It’s Worth It
Big questions about ‘challenge trials’ to test vaccines might be addressed while ethical and scientific preparation starts.
Jonathan Jackson | Harvard Catalyst Profiles | Harvard Catalyst
Steve Joffe
5/ @egaly, whose work addresses equity and inclusion in clinical research (and has a side gig in cognitive neuroscience to boot).
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Raina M. Merchant, MD, MS
Dr. Raina M. Merchant is an Associate Vice President at Penn Medicine and an Associate Professor of Emergency Medicine at the University of Pennsylvania. She has secondary appointments in the