Stefan Flasche
Associate Professor at LSHTM, math. modeller, epidemiologist, vaccinologist, pneumococcologist
Thought Leader
| #31 | Infectious Disease |
Last synced from Twitter 4h ago
Impact of COVID-19 lockdown on routine immunisation in Karachi, Pakistan
The swift spread of COVID-19 has upended health systems and affected all health services.
The disruption of routine immunisation services could start secondary outbreaks of
vaccine-preventable diseases and also worsen the longstanding inequity in...
HIV in a pandemic - Early diagnosis is more crucial than ever | LSHTM
I took off my face mask when I arrived home from the health centre with my daughter, who had just received her final round of infant vaccines. The outing left me filled with gratitude that I have such ready access to medical resources to protect...
Number of HIV-1 founder variants is determined by the recency of the source partner infection
HIV-1 has a multitude of strain variants, but sexual transmission of HIV-1 is assumed to result from productive infection by only one virus particle. Knowing the genetics of the virus strains that are transmitted could be crucial for developing...
Capacity development for disease outbreak and epidemic response in sub-Saharan Africa, in collaboration with Africa CDC - EDCTP
Expected number of grants: 7-10 grants Call Identifier: CSA2020E Project Officer: Shingai Machingaidze, contact via [email protected] Download Call text (PDF)
Distancing rules relaxed for children in Scotland
Those under 12 will not have to follow distancing rules outdoors, while older children can meet more people during a day.
The need for evidence we can trust - large international trial finds drug used to treat gastric bleeding does not work | LSHTM
For my 40 birthday I got a new brother. Not a scrawny, screaming, baby brother but a corpulent, competent, pillar of the community big brother. An old friend, having drunk his fill, found himself unable to keep his secret for a single second longer...
Stefan Flasche
recommended read
7d
Gates Open Research Article: Younger ages at risk of Covid-19 mortality in communities of color.
Read the latest article version by Keith P. Klugman, Solomon Zewdu, Barbara E. Mahon, Scott F. Dowell, Padmini Srikantiah, Kayla F. Laserson, Jordan W. Tappero, Anita K. Zaidi, Trevor Mundel, at Gates Open Research.
UK exceeds 200,000 testing capacity target
The UK had capacity to conduct 205,634 tests on Saturday, reaching its target one day early.
Stefan Flasche
>200,000 #COVID19
tests per day is great. But the lack of processing speed (about 3-5 days from symptoms to confirmed test) brings some massive challenges for effective contact tracing
18d
Germany's coronavirus reproduction rate jumps to 1.79: RKI
The reproduction rate of the novel coronavirus in Germany has jumped to 1.79 after a raft of localised outbreaks, the Robert Koch Institute (RKI) for public health said on Saturday, far above the level needed to contain it over the longer term.
Use of seasonal influenza and pneumococcal polysaccharide vaccines in older adults to reduce COVID-19 mortality
1
Stefan Flasche
And out now:
effectiveness of pneumococcal and flu vaccine for limiting the effect of co-infections with COVID.
sciencedirect.com/science/articl… twitter.com/deusthindwa/st…
20d
COVID-19: paediatric surveillance
Description and contact details of PHE paediatric surveillance programmes for COVID-19.
Life-saving coronavirus drug has been found
Experts say there should be no delay in getting the cheap drug to patients after "fantastic" trial results.
Stefan Flasche
Some good news: Dexamethasone can reduce mortality in very severe #COVID19 cases by up to 33%. And its widely available
23d
Global, regional, and national estimates of the population at increased risk of severe COVID-19 due to underlying health conditions in 2020: a modelling study
About one in five individuals worldwide could be at increased risk of severe COVID-19,
should they become infected, due to underlying health conditions, but this risk varies
considerably by age. Our estimates are uncertain, and focus on underlying...
The Dos and Don’ts of ‘Quarantine Pods’
It might be awkward, difficult and even risky. But joining a social bubble might just save your sanity.
IDDjobs — Research fellow opportunity modelling influenza infection, vaccination and antibody dynamics (4 year post) — London School of Hygiene & Tropical Medicine
Find infectious disease dynamics modelling jobs, studentships, and fellowships.
Estimating the contribution of different age strata to vaccine serotype pneumococcal transmission in the pre vaccine era: a modelling study
Herd protection through interruption of transmission has contributed greatly to the impact of pneumococcal conjugate vaccines (PCVs) and may enable the use of cost-saving reduced dose schedules. To aid PCV age targeting to achieve herd protection,...
9
Stefan Flasche
New manuscript:
pneumococci mainly transmits among young kids .
BUT, older children may also contribute substantially in LMICs 👉 they are likely not reached by PCV 👉 may explain the reduced herd protection in LMICs.
👇
29d
The effectiveness of social bubbles as part of a Covid-19 lockdown exit strategy, a modelling study
We consider expanding the social bubble of either all households or only single occupance households or households with young children. We assess how the implementation of these strategies during lockdown impacts on the risk for Covid-19 resugence.
12
Stefan Flasche
Social bubbles for #COVID19 are effective but will need to be used only if needed and while applying common sense infection control.
new preprint with the great @WarwickSBIDER bunch and @cmmid_lshtm: cmmid.github.io/topics/covid19… pic.twitter.com/B93dWfcBPS
33d
No new COVID sufferers, 300 asymptomatic, after Wuhan-wide tests
The Chinese city of Wuhan, where the novel coronavirus outbreak began, has found no new cases of people suffering from COVID-19 after testing almost its entire population, and 300 asymptomatic carriers of the virus, officials said on Tuesday.
Stefan Flasche
Struggling to make sense of this:
~10mil tested in Wuhan (x-sectional) -> found 300 asyptomatic (with no evidence of shedding) & 0 symptomatic
Is the best explanation for this, that test specificity is "just" 99.995%? I.e. the 300 are false positives?
33d
Malaria drug 'does not save lives' from coronavirus
Hydroxychloroquine has become controversial but it is not a treatment for Covid, say Oxford researchers.