The AACR’s educational workshops provide early-career investigators with opportunities to develop skills in clinical trial design, molecular biology, integrative molecular epidemiology, translational research, and related fields.
Bodenmiller and colleagues pair imaging mass cytometry with data from the METABRIC cohort to define single-cell phenotypic and genomic features of breast cancer with spatial context, finding associations with breast cancer subtypes and prognosis.
A framework of patient-partnered research allows patients with angiosarcoma to share their samples and clinical records securely to accelerate molecular characterization of tumors and identification of therapeutic approaches.
The cost of cancer can be measured in many ways. The human toll is steadily declining, with cancer deaths down 27 percent since their peak in 1991. But while...
Daniel Stover, MDWhat happens to leftover oral cancer meds?
Important cancer drug take-back program @OSUCCC_James to get costly meds to patients in need, avoiding waste/cost & #financialtoxicity
Check out this video, starring @ChefGeib
Gaglia et al. show, using single-cell imaging and analysis in human tumours, that phase transition of heat-shock factor 1 (HSF1) to form intranuclear stress bodies mediates cell-fate decisions underlying cell survival or death.
The male germline cells in human and mice balance the protection of genomic integrity
and the evolutionary benefit of genetic mutations through transcriptional scanning,
a mechanism that preferentially couples efficient DNA damage repair with high...
Circulating cell-free DNA (cfDNA) is shed in the bloodstream by normal and tumor cells and is a valuable liquid biopsy tool. This protocol describes a low-input approach to enrich methylated DNA fragments from cfDNA and prepare sequencing libraries.