Kevin Mitchell
I am a neurogeneticist interested in the genetics of brain wiring and its contribution to variation in human faculties. Author of INNATE (2018). kjmitchell.com
Thought Leader
| #388 | The New Center |
Last synced from Twitter 17m ago
No evidence for a bilingual executive function advantage in the nationally representative ABCD study
By analysing data from more than 4,500 9- to 10-year-olds, Dick et al. found no evidence that bilingual children have an advantage in executive functions, the cognitive abilities that are central to the voluntary control of thoughts and behaviours.
The Bitter Fight Over the Benefits of Bilingualism
For decades, some psychologists have claimed that bilinguals have better mental control. Their work is now being called into question.
Has the Genome Granted Our Wish Yet? | NEJM
Perspective from The New England Journal of Medicine — Has the Genome Granted Our Wish Yet?
What Changed My Mind About Climate Change?
I spent the better part of my professional life (1991-2014) working at a libertarian think tank—the Cato Institute—arguing against climate action. As Cato’s director of Natural Resource Studies (and later, as a senior fellow and eventually vice...
MICA-MNI/micaopen
Open Scripts / Pipelines from the Multimodal Imaging and Connectome Analysis Lab - MICA-MNI/micaopen
Microstructural and functional gradients are increasingly dissociated in transmodal cortices
Modelling cortico-cortical networks of microstructural similarity in post mortem and in vivo brains reveals consistent gradients of microstructural differentiation running from sensory to transmodal cortices, and allows single-subject investigation...
All parents are environmentalists until they have their second child | Behavioral and Brain Sciences
All parents are environmentalists until they have their second child - Volume 10 Issue 1 - Marvin Zuckerman
MyHeritage Expands to Health; Launches New DNA Test Offering Powerful and Personalized Health Insights for Consumers
MyHeritage Expands to Health; Launches New DNA Test Offering Powerful and Personalized Health Insights for Consumers.
Genetic Information Nondiscrimination Act (GINA) | ASHG
Enacted in 2008, GINA is a federal law that protects against genetic discrimination in the workplace and through one’s health insurance.
Genetic Associations Between Executive Functions and a General Factor of Psychopathology
Symptoms of psychopathology covary across diagnostic boundaries, and a family history
of elevated symptoms for a single psychiatric disorder places an individual at heightened
risk for a broad range of other psychiatric disorders. Both twin-based...
Oxford Launches TAP-Style Foundation Course
The new programme will see 50 students accepted to study on a one-year foundation course.
The network architecture of the human brain is modularly encoded in the genome
The form of genotype-phenotype maps are typically modular. However, the form
of the genotype-phenotype map in human brain connectivity is unknown. A modular
mapping could exist, in which distinct sets of genes' coexpression across brain
regions is...
A terminal selector prevents a Hox transcriptional switch to safeguard motor neuron identity throughout life
Nervous system function critically relies on continuous expression of neuron type-specific terminal identity features, such as neurotransmitter receptors, ion channels and neuropeptides. How individual neuron types select such features during...
Kevin Mitchell
A terminal selector prevents a Hox transcriptional switch to safeguard motor neuron identity throughout life biorxiv.org/content/10.110… - how does a neuron retain its identity? pic.twitter.com/46kkhqWUk9
24h
Acute inflammation alters energy metabolism in mice and humans: Role in sickness-induced hypoactivity, impaired cognition and delirium.
Systemic infection can result in a spectrum of metabolic and behavioral changes, termed sickness behavior, an organismal reprioritization that suppresses activity, conserves energy, and maximizes the probability of recovery. In vulnerable...
Genetic overlap between psychiatric disorders and neuropsychiatric symptoms in HD
Huntington’s disease (HD) is an inherited neurodegenerative disorder caused by an expanded CAG repeat in HTT . It is diagnosed following a standardized exam of motor control and often presents with cognitive decline and neuropsychiatric signs and...
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Kevin Mitchell
Genetic overlap between psychiatric disorders and neuropsychiatric symptoms in HD biorxiv.org/content/10.110… - very interesting. To me => polygenic risk indexes genomic robustness -> developmental robustness -> neural reserve pic.twitter.com/TsoN2X6xCR
37h
Contribution of Retrotransposition to Developmental Disorders
Mobile genetic Elements (MEs) are segments of DNA which, through an RNA intermediate, can generate new copies of themselves and other transcribed sequences through the process of retrotransposition (RT). In humans several disorders have been...
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Kevin Mitchell
Contribution of Retrotransposition to Developmental Disorders biorxiv.org/content/10.110… - it happens, but it's very rare pic.twitter.com/WKQd7rc68f
37h
How to grow a human
Join Philip Ball as he discusses the new technologies of cell reprogramming that were used to make his