I am a neurogeneticist interested in the genetics of brain wiring and its contribution to variation in human faculties. Author of INNATE (2018). kjmitchell.com
To study the dynamics of neural processing across timescales, we require the ability to follow the spiking of thousands of individually separable neurons over weeks and months, during unrestrained behavior. To address this need, we introduce the...
There has been considerable debate about the placement of the root in the animal tree of life, which has emerged as one of the most challenging problems in animal phylogenetics. This debate has major implications for our understanding of the...
Identifying rare genetic causes of common diseases can improve diagnostic and treatment strategies, but incurs high costs. We tested whether individuals with common disease and low polygenic risk score (PRS) for that disease generated from less...
In this Primer article, Bijsterbosch and colleagues provide an accessible discussion of the challenges faced in analytical representations of functional brain organization and provide clear recommendations to unite a fractionated field.
The Free Energy Principle and Active Inference Framework (FEP-AI) begins with the understanding that persisting systems must regulate environmental exchanges and prevent entropic accumulation. In FEP-AI, minds and brains are predictive controllers...
Ordinary human experience is embedded in a web of causal relations that link the brain
to the body and the wider environment. However, there might be conditions in which
brain activity supports consciousness even when that activity is fully causally...
A handful of experiments are raising questions about whether clumps of cells and disembodied brains could be sentient, and how scientists would know if they were.
What does the birth of babies whose embryos have gone through genome editing mean—for science and for all of us?
In November 2018, the world was shocked to learn that two babies had been born in China with DNA edited while they were...
We (Neuro graduate students at Berkeley) are having an application Zoom panel! Fill out this form to receive a Zoom link to the live event and a recording of the event afterwards. This questionnaire is intended to tell us more about you and inform...
During development the vast majority of cells that will later compose the mature cerebral cortex undergo extensive migration to reach their final position. In addition to intrinsically distinct migratory behaviors, cells encounter and respond to...
Brain morphology has been shown to be highly heritable, yet only a small portion of the heritability is explained by the genetic variants discovered so far. Here we exploit the distributed nature of genetic effects across the brain and apply the...