Antonio Regalado
Progress in science depends on new techniques, new discoveries and new ideas, probably in that order - {Sydney Brenner}. I write about biotechniques @techreview
Last synced from Twitter 5m ago
Why Democrats reopened the debate about germline gene editing
Democrats in Congress considered lifting a ban on genetically modifying embryos for use in pregnancy. Why now, just months after the CRISPR babies scandal?
Russian geneticist answers challenges to his plan to make gene-edited babies
Denis Rebrikov will use CRISPR on the same gene a China team did, but he has a different rationale
3
Antonio Regalado
Pretty juicy interview between @sciencecohen and would-be CRISPR baby maker in Russia. sciencemag.org/news/2019/06/r… pic.twitter.com/ZS8RChYgNG
10d
Dr. Josiah Zayner v California Department of Consumer Affairs
On May 8th I received a letter from the California department of consumer affairs saying that I was under investigation for practicing medicine without a lic...
Jiankui He CRISPR Babies
Talk at Human Genome Editing Summit, Hong Kong, Nov 28 2018
Antonio Regalado
I am looking for a better quality version of this fascinating moment at the Hong Kong Genome Editing summit when He Jiankui walks onto the stage. A man under enormous pressure, i would say. Anyone know of a better version?
11d
GSK partners with CRISPR pioneer Doudna to find new drugs
GlaxoSmithKline will team up with some of the nation’s most prominent CRISPR researchers to use the gene-editing technology in a search for new medicines.
7
Antonio Regalado
GSK forms CRISPR alliance with UC Berkeley and UCSF to create functional genomics insitute. Coupla of points ought to be added (thread).
11d
CRISPR-Based Tool Maps Gene Function in Human Cells
UCSF scientists have used a high-throughput CRISPR-based technique to rapidly map the functions of nearly 500 genes in human cells, many of them never before studied in detail.
1
Antonio Regalado
The main one, technologywise, is this about using CRISPR as a gene function screen. I can't explain it, but in short, you can do a gazillion experiments at once, fleshing out connections, sketching the biology, finding drug targets.
11d
External review on Novartis agreement
2
Antonio Regalado
People don't seem to recall or much care a very similar deal in 1999, between Novartis and UC Berkeley, caused an absolute sh*tstorm, and headlines like "The Kept University." in fact, no one even seemed to be aware of this history
11d
Biden promises he'll cure cancer if elected president
Joe Biden told an audience in Ottumwa, Iowa Tuesday that his White House would "cure" cancer should he beat President Trump in 2020.
Humanism and Transhumanism
With Natasha Vita-More, Rob Riemen, Kassem Eid, Leon Wieseltier and Miroslav Volf. Nexus Conference 2018, ‘The Battle between Good and Evil’ in Amsterdam. Se...
Antonio Regalado
Natasha Vita Moore. Studies memory preservation in vitrified worms. Married to Max More, Alcor CEO. “We are in...a human transition to becoming something other...could be an evolved human, a human emerging with artificial intelligence..." youtube.com/watch?v=oeVr7I… pic.twitter.com/TvarfcQJEM
12d
A CRISPR startup is testing pig organs on monkeys to see if they’re safe for us
Gene-editing company eGenesis is now carrying out experiments to help solve a critical shortage of human organs available for transplant.
Antonio Regalado
7/ egenesis got a lot of notoriety when they used CRISPR to zap all 62 copies of a virus that hands out inside the pig genome.
12d
Antonio Regalado
Kinda well-known CRISPR company eGenesis is testing pig organs in unspecified primates at Mass General. Story by Karen Weintraub 1/ (thread)
12d
Transgenic Pigs Shatter Transplant Records
A biotech company is genetically engineering pigs so that their organs might work in people.
Antonio Regalado
5/ A different company, Revivicor, is further advanced. It's organs have been tested many times by many hospitals. They have been beating records, with organs surviving a year or more. Revivicor also employs CRISPR gene editing now
12d
CarnegieInstitution Live Stream
Antonio Regalado
2/ Company is a xenotransplant spinout of George Church lab. I was real surprised when Church started saying, in 2017, there would be human tests of these organs "within a year". See that here.
12d
Russia: Putin warns a GM human could be 'worse than nuclear bomb'
Russian President Vladimir Putin heeded a warning that one day mankind will break the genetic code and create something that could be “worse than a nuclear b...
1
Antonio Regalado
In 2017, Russian President Vladimir Putin, told students at the Sochi Youth Festival that genetic engineering could create soldiers that feel no pain and be “worse than a nuclear bomb”.
Here's the clip (in Russian). youtube.com/watch?v=E6pD96… twitter.com/antonioregalad…
14d
A Russian scientist has threatened to make more CRISPR babies
A Russian biologist has told a journalist at Nature that he wants to create more gene-edited babies and will do it if he can win approval.Who’s involved: Denis Rebrikov of the Pirogov Russian National Research Medical University in Moscow says he...
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The efficacy of CRISPR-Cas9-mediated induction of the CCR5delta32 mutation in the human embryo
<p>The editing of the CCR5 gene in the CD4<sup>+</sup> T cell genome is an effective way of preventing HIV-1 proliferation. Very similar strategies can be used to protect the fetus ...
2
Antonio Regalado
updated embryo editing scorecard. tally of papers describing embryo editing with CRISPR, by country.
🇨🇳:9
🇺🇸:1
🇬🇧:1
🇷🇺:1
RUSSIA just added because of this paper, describing CCR5 edits to embryos
14d
Russian biologist plans more CRISPR-edited babies
Discover the world’s best science and medicine | Nature.com
DNA Site That Helps Cold-Case Sleuths Curbs Access for Police
The genealogy database that helped authorities track down the alleged Golden State Killer and dozens of other suspects has changed a key policy over privacy concerns, a move that could hamper future criminal investigations.