Talk at Human Genome Editing Summit, Hong Kong, Nov 28 2018
Antonio RegaladoI am looking for a better quality version of this fascinating moment at the Hong Kong Genome Editing summit when He Jiankui walks onto the stage. A man under enormous pressure, i would say. Anyone know of a better version?
UCSF scientists have used a high-throughput CRISPR-based technique to rapidly map the functions of nearly 500 genes in human cells, many of them never before studied in detail.
Antonio RegaladoThe main one, technologywise, is this about using CRISPR as a gene function screen. I can't explain it, but in short, you can do a gazillion experiments at once, fleshing out connections, sketching the biology, finding drug targets.
Antonio RegaladoPeople don't seem to recall or much care a very similar deal in 1999, between Novartis and UC Berkeley, caused an absolute sh*tstorm, and headlines like "The Kept University." in fact, no one even seemed to be aware of this history
A biotech company is genetically engineering pigs so that their organs might work in people.
Antonio Regalado5/ A different company, Revivicor, is further advanced. It's organs have been tested many times by many hospitals. They have been beating records, with organs surviving a year or more. Revivicor also employs CRISPR gene editing now
Antonio Regalado2/ Company is a xenotransplant spinout of George Church lab. I was real surprised when Church started saying, in 2017, there would be human tests of these organs "within a year". See that here.
A Russian biologist has told a journalist at Nature that he wants to create more gene-edited babies and will do it if he can win approval.Who’s involved: Denis Rebrikov of the Pirogov Russian National Research Medical University in Moscow says he...
Antonio RegaladoICYMI -- Russian scientists feeling gung ho about genetically modified humans.
<p>The editing of the CCR5 gene in the CD4<sup>+</sup> T cell genome is an effective way of preventing HIV-1 proliferation. Very similar strategies can be used to protect the fetus ...
Antonio Regaladoupdated embryo editing scorecard. tally of papers describing embryo editing with CRISPR, by country.
RUSSIA just added because of this paper, describing CCR5 edits to embryos
The genealogy database that helped authorities track down the alleged Golden State Killer and dozens of other suspects has changed a key policy over privacy concerns, a move that could hamper future criminal investigations.