Cold Spring Harbor Laboratory trustees vote on future of graduate school Cold Spring Harbor Laboratory (CSHL) was established as a biological teaching laboratory in 1890. With a long history as a scientific meeting center and research institute, it...
The COVID-19 virus isn't just devastating, it's devastatingly clever, hijacking the power of our own cells in novel ways to make itself more dangerous. But now a team at UCSF is hoping to turn one of the virus's own weapons against it.
Macrophages are components of the innate immune system with key roles in tissue inflammation and repair. It is now evident that macrophages also support organogenesis, but few studies have characterized their identity, ontogeny and function during...
A high-resolution atlas of regulatory elements driving regional, temporal, and laminar
gene expression programs in the developing human telencephalon reveals enhancers and
genetic variants regulating human disease genes.
Congenital heart disease (CHD) is the most common birth defect. Fetal survey ultrasound is recommended worldwide, including five views of the heart that together could detect 90% of complex CHD. In practice, however, sensitivity is as low as 30%. We...
Phosphoproteomics analysis of SARS-CoV2 infected VERO-6 cells reveals host cellular
pathways hijacked by viral infection, and analysis of signaling profiles identifies
small molecules targeting dysregulated pathways, many of which possess potent...
Burton et al. show that H3K9me3 deposition catalysed by SUV39H2 and regulated by pericentromeric RNAs in the mouse paternal pronucleus does not suppress gene expression, but bookmarks promoters for compaction.
The Portishead singer and conductor (and film-music icon) Krzysztof Penderecki deliver a surprisingly disquieting take on Górecki’s canonical symphony, a piece so familiar that it’s often taken for granted.
Benoit Bruneauyou know what the cool kids are listening to? Krzysztof Penderecki is who! Booyah!