Tami Lieberman
Microbiology, evolution, genomics. Thinking about the ~10^9 mutations generated in your skin and gut microbiomes daily. Asst Prof @MIT_IMES @MIT_CEE.
Thought Leader
| #227 | Infectious Disease |
Last synced from Twitter 79d ago
Viral dynamics of SARS-CoV-2 infection and the predictive value of repeat testing
SARS-CoV-2 diagnostics that report viral RNA concentrations can be used to determine a patient's stage of infection, but this potential has not yet been realized due to a lack of prospective longitudinal data to calibrate such inferences. Here, we...
Micron Scale Spatial Measurement of the O2 Gradient Surrounding a Bacterial Biofilm in Real Time
Bacteria alter their local chemical environment through both consumption and the production of a variety of molecules, ultimately shaping the local ecology. Molecular oxygen (O2) is a key metabolite that affects the physiology and behavior of...
samsinai/FLEXS
Fitness landscape exploration sandbox for biological sequence design. - samsinai/FLEXS
Long-run bacteria-phage coexistence dynamics under natural habitat conditions in an environmental biotechnology system
Bacterial viruses are widespread and abundant across natural and engineered habitats. They influence ecosystem functioning through interactions with their hosts. Laboratory studies of phage–host pairs have advanced our understanding of phenotypic...
Southern Chinese populations harbour non-nucleatum Fusobacteria possessing homologues of the colorectal cancer-associated FadA virulence factor
Objective Fusobacteria are not common nor relatively abundant in non-colorectal cancer (CRC) populations, however, we identified multiple Fusobacterium taxa nearly absent in western and rural populations to be comparatively more prevalent and...
Dermatology Bootcamp - MGH Psychiatry Academy
A crash course in everything you wanted to know about the skin, hair, and nails for healthcare professionals of all backgrounds.
Rational design of a microbial consortium of mucosal sugar utilizers reduces Clostridiodes difficile colonization
Here, the authors employ Raman-Activated Cell Sorting (RACS) and metagenomics to identify organisms that can forage on O-glycan monosaccharides in the mouse gut, which they use to construct a bacterial consortium able to reduce Clostridioides...
Highly Variable Mutation Rates in Commensal and Pathogenic Escherichia coli
E scherichia coli in humans is a commensal inhabitant of the gastrointestinal tract as well as one of the most frequently isolated bacterial pathogens ([1][1]). In studying food- borne E. coli pathogens, as well as the ECOR collection of natural...
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Tami Lieberman
@acritschristoph Hypermutators have long been shown to be common in the wild
94d
Amy Coney Barrett Promises Catholic Faith Won’t Interfere With Court’s Crushing Of The Poor, Downtrodden
WASHINGTON—In an effort to assure critics during her Senate confirmation hearing for the Supreme Court, Judge Amy Coney Barrett promised Monday that her Catholic faith’s tenets of generosity and humanity would not interfere with her duty on the...
Intercellular telomere transfer extends T cell lifespan
The common view is that T-lymphocytes activate telomerase, a DNA polymerase that extends telomeres at chromosome ends, to delay senescence. We show that independently of telomerase, T cells elongate telomeres by acquiring telomere vesicles from...
Whitehead Seminar Series for High School Teachers
Whitehead Institute for Biomedical Research is a non-profit, independent research and educational institution known as a world leader in biomedical research.
Defining and Manipulating B Cell Immunodominance Hierarchies to Elicit Broadly Neutralizing Antibody Responses against Influenza Virus
Antibodies against the hemagglutinin (HA) spike protein of influenza virus naturally
target immunodistractive features rather than conserved sites that confer broad neutralization.
Amitai et al. resolve drivers of immunodominance computationally and...
Evolutionary Dynamics, Oct 9
Center for the Physics of Biological Function symposium
Friday, October 9, 2020 on Zoom
10:00 AM - 3:30 PM EDT
10:00 - 11:30 Tracking and predicting viral evolution, from flu to covid-19
RICHARD NEHER, Richard Neher, University of Basel
12:00 -...
Other
Fellowship applications I am grateful to have been funded by the NSF GRFP, Hertz Foundation graduate fellowship, and James S. McDonnell Foundation postdoctoral fellowship. I learned a lot by readin…
Three from MIT receive National Health Institute Awards
MIT faculty members Michael Birnbaum, Anders Hansen, and Tami Lieberman have each been selected to receive the 2020 New Innovator Award from the National Institute of Health (NIH)
Pioneers of revolutionary CRISPR gene editing win chemistry Nobel
Emmanuelle Charpentier and Jennifer Doudna share award for the powerful technology that makes precise changes to the genome.
Metastable hybridization-based DNA information storage to allow rapid and permanent erasure
The chemical stability of DNA makes complete erasure of DNA-encoded data difficult. Here the authors mix true and false messages, differentiated by whether a truth marker oligo is bound to it, and show that brief exposure to elevated temperatures...