A fascinating triad of papers on a gene pathway (ADCY3) related to #obesity and #diabetes w/ roots at #brain neuronal "antennae" (cilia)
Really happy to see this paper online today and proud to be joint first author on it!
ADCY3 mutation increases risk of #obesity and #type2diabetes in Inuit
Loss-of-function variants in ADCY3 increase risk of obesity and type 2 diabetes. Great story and a nice collaboration!
Loss-of-function variants in ADCY3 increase risk of #obesity and type 2 #diabetes