Promo: releases CAR-T trials mid-2018 update: 115 CAR cell trials registered first 1/2 of this year, 41% outside . 51% increase in # of trials vs 1/2 of last year and the # of late phase trials is on track to double
According to this lawsuit, a registered "study" on the website played a role in luring a patient to a Florida-based stem cell clinic marketing unproven & unlicensed stem cell interventions for eye-related diseases.
So, uh, searching data from using different gene synonyms returns vastly different results: Search for CD274=190 studies Search for PD-L1=1147 studies #bioinformatics
They say good things come in threes. We've had #Christmas and #NewYear. To complete the set here's our December Research Round-up. Please retweet. For more details about the clinical trial in the video, visit and search 'HARPdoc'
Men at High Genetic Risk for Prostate Cancer - Full Text View - . ⁦⁩ great talk #GU19 Thought this might be of interest ⁦⁩ ⁦⁩ ⁦
There is a fundamental paradox in the revised #ISCHEMIAtrial. Here is the first inclusion criteria on
New #NCTN disease portfolio diagrams show trials that are active (including temporarily closed) for a specific disease area, with links to the page. More information:
Here is a Hennepin 'ketamine study' listed on as randomized, double-blinded interventional clinical trial. That study is withdrawn. Published version is "prospective open label study" done with "Waiver of Consent (45 CFR 46.116.)"
The “lockbox” allows a sponsor of a device trial in to deposit the registration data but to shield it from public view. This letter reviews its use since January 2017.
. & team now reporting trials overdue on reporting results on let’s hope this provides impetus for no trial to be overdue. #publicationbias contaminates our literature; invalidates systematic reviews. Time for change.
The current landscape of AF/AFL trials: An in-depth analysis of the database by et al in this month's #JACCCEP: .
A seminal event has occurred, which is the listing of the Novartis Lp(a) CVOT on . NCT04023552. Details can be found here: . The study will be called Lp(a) HORIZON and will have entry criteria Lp(a)> 70 mg/dL with hx CVD events.
How to avoid common problems when using in research: 10 issues to consider
"Fake clinics are claiming their work is legitimate just because they're on - they're using it as a marketing tool"
Thrilled to announce the ROS1 PDX study is now available on ! Patients can now enroll to help drive research into new treatments. Call Nurse Alicia to learn more! (866) 988-ROS1. #ROS1 #lcsm
$JUNO $CELG JCAR015 ROCKET results posted on (terminated after 5/38 pts w/ cerebral edema)
People who have read a bit about a reproducibility crisis in psychology and have never worked on a clinical trial, jumping on a protocol amendment as proof of fraud. Keep doing what you’re doing guys. You are the best cure for imposter syndrome.
The median time from a press release referencing trial results until either publication or posting on is 300 days.
Updated #ETCTN disease portfolio diagrams show trials that are in review, approved, and active for a specific disease area, with links to the page for active trials: (pdf)
One of the saddest parts of our week () was searching for CAR-T/NK studies on for our patient living with HIV and lymphoma, and seeing HIV in the exclusion criteria of every study. We need to be safe but we also need progress for all patients
new trial at MD Anderson treating mycosis patients with ultra low dose radiation ONLY 4 Gy. even if ulcerated lesion low dose is the answer, No 30 Gy in 10 any more, these doses are harmful to the skin. Identifier:NCT03398161
Men at High Genetic Risk for Prostate Cancer - Full Text View - ⁩ ⁦⁩ Contact Anna [email protected] for our study screening men at high genetic with prostate MRI
The median time between pharmaceutical company press release and publication in oncology is 283 days for positive results and 590 days for negative results. (Less, 202 and 407 days, if you count posting on ).
While registration of a published trial is good, a question to ask is what studies of this drug haven't been published? Many registered studies aren't published >8yrs after registration: #ARM18 #ARM2018
600 trials a week coming into but nowhere near that many show up in journals or results in registries: Zarin #FNLM
Registering behavioral studies on could affect how participants behave!
Actually, there’s some confusion about who is actually sponsoring the on-going Penn CRISPR trial. A recent slide deck said that and are the sponsors whereas lists as the sponsor.
Study started in 2015, finished in 2016, and submitted to in 2017. ... Is this normal?
Registering behavioral studies on could affect how participants behave!
It could be the first US CRISPR trial. That U Penn study using CRISPR -ized T cells to fight cancer is finally up on
>400 research articles btwn 2010-15 reported data from but how many used the database properly? Free guide explains its capabilities and limitations
>400 research articles btwn 2010-15 reported data from but how many used the database properly? Free guide explains its capabilities and limitations
The registry of the new intermittent fasting study (NCT02673515) in has 1 primary outcome (insulin sensitivity) & 8 secondary outcomes. The paper fails to report the primary outcome or 7/8 secondary outcomes. WTF?!
Rigorous QI design guidelines from ☑️ generalizable results ☑️ evaluate safety & cost outcomes ☑️ concurrent control group, randomization or blinding ☑️ IRB approval & registration at ☑️ SQUIRE guided reporting
As of June, over 300 clinical trials have been registered at under the headings #ArtificialIntelligence #MachineLearning or #DeepLearning. Read about the development of AI-specific extensions to the CONSORT and SPIRIT statements:
Nov 7: Deborah Zarin, A window into the Clinical Research Enterprise, McGill University
Prospective study of intensive strategy in 5 systematic reviews: no impact on results or conclusions. 13/173 trials had results but no publication
Prospective study of intensive strategy in 5 systematic reviews: no impact on results or conclusions. 13/173 trials had results but no publication
$GERN results update today reveals that Imetelstat's NCI brain tumor trial was terminated due to several intracranial hemorrhages and recommendation by the DSMB
How to avoid common problems when using in research #ResearchMethods&Reporting article discusses 10 key issues that researchers need to consider when using the database to conduct research
Tomorrow, Wed, June 6th. Free webinar, noon-1PM ET, on how to use and the #ExpandedAccess navigator. Speakers from #ClinicalTrials.gov and from the Reagan Udall Foundation for the FDA.Plenty of time for questions! Register at
'The difference between medicine and poison is in the dose'- is that why you are now omitting dose and dosing scheme from your clinical trials submissions to
it appears all studies that deliver an intervention to healthy participants--behavioral or biomedical--will need to be registered on and will be considered a #Clinicaltrial
Number of digital health studies registered in is rising year over year, but most are small (median 120 patients), few have reported results (even among those that are completed)
How are some clinics using to disguise unregulated #stemcell treatments as #clinicaltrials? Read more in this perspective from .
Secondary source databanks and accession numbers such as , GenBank, figshare, and Dryad are now displayed under a new section titled “Associated data” in #PubMed #opendata
🇫🇷 France is leading the field in terms of Clinical Trials using Fecal Microbiota Transfer as a modality - There is a terrific ecosystems in France: Scince/Academics; Regulators; Investors; Biotech -- source
Amid FDA crackdown, stem cell clinics are still listing "studies" on , muddying the waters for patients looking for legitimate trials.
How to avoid common problems when using in research: 10 issues to consider
NIH is extending the flexibility for registering and reporting basic experimental studies with humans (BESH) in alternative platforms for an additional 2 years, based on feedback from the community citing challenges using .
In-depth analysis of database in #JACCCEP reveals 348 registered AF/AFL trials. Check it out: .
You can look up all the trials registered that mention Apple watch on . There are 20. None that I can see show that Apple watch improves health or reduces cost. If the Apple watch were a pill insurers wouldn't pay for it.
One key initiative announced by was that NCT#s for the registry would be required for all postmarketing studies, and would be embedded and linked to the regulatory materials (which would be a huge help) 6/8
A recent study found that 4 weeks of antibiotics treatment can prevent active tuberculosis in people living with #HIV. Read more about the sponsored trial at
Have you ever wrestled with This handy pub might help:
Reflecting today on how much I ❤️. In 2005, we posted , analyzing reasons for terminating clinical trials from . It didn’t fit the mold for journals & talented student moved on. We gave up on it. 1/2
Pfizer has established an expanded access treatment protocol to make tafamidis available to ATTR-CM patients who may benefit from treatment prior to regulatory approval. The expanded access treatment protocol is posted on (NCT02791230)
This is important, not just because of the extra administrative burden, not just because it would bury actual clinical trials under mountains of basic research on , but because of the confusion it will create for our participants and the public. 1/3
According to , there are over 250,000 trials on the database today. How are cancer trials unique? Check out our video at Clinical Trials Awareness Week #CTAW2018
Of 692 total autism trial registrations currently on , 69 (10%) are "unknown status" i.e. they've been abandoned
A good reminder of how fields can learn from one another: shows that creation of was associated with fewer positive findings, smaller effect sizes. #metascience2019
... this unreported trial by PHE finished in 2016. Today they told the BBC they have reported their results on . This is untrue. Here are all the studies on with PHE listed anywhere as sponsor. No results for any of them...
A1. Hard to find when initially dx - Dr/HCP not often bringing up #Clinicaltrial as possible care option. Hard to find when searching govt registries; is still difficult to understand, navigate #PatientsFirst
T5: some trials, particularly for rare genomic subsets, will often help arrange or reimburse travel to the nearest clinical site. Contact information for each trial would be on #LCSM
... this unreported trial by PHE finished in 2016. Today they told the BBC they have reported their results on . This is untrue. Here are all the studies on with PHE listed anywhere as sponsor. No results for any of them...
Sequencing of Stereotactic Ablative Body Radiotherapy in Combination With PD-1 Blockade Using Pembrolizumab in Metastatic Non-Small Cell Lung Carcinoma - Full Text View - via thanks
Study shows is a key resource to identify #prescriptiondrug trial results via researchers at
Me too... Someone with influence must have just submitted a grant and had to deal with the tedious clinical trials Forms-E requirements or had to upload a bunch of studies to ;)
. tried to see how hard it was to find clinical trials in . She found 9001 trials for breast cancer alone! A better, more user-friendly system is needed to help patients navigate the depths of ! #ASCO19
. tried to see how hard it was to find clinical trials in . She found 9001 trials for breast cancer alone! A better, more user-friendly system is needed to help patients navigate the depths of ! #ASCO19
Check out #ETCTN disease portfolio diagrams' colorful new look at . ETCTN disease diagrams are updated monthly to show trials that are in Review, Approved, or Active for a specific disease area, with links to for Active trials.
Got #clinicalresearch ? Right now there are 64 studies recruiting for #migraine , 7 for #clusterheadache , 10 for #posttraumatic headache, 4 for #trigeminalneuralgia . Make a difference!
JC for trainees is not about the paper. It is about how to read the paper. * RCT - read design paper * Review analysis plan * Review entry & changes to it * Are appropriate controls used? * Analytic issues? * Missing data? * Other threats fo validity?
DYK? Our INSIGHT-MM study tracks patterns in patients' real-world experience w/ #myeloma therapies
A fraction of advanced cell therapy trials, registered worldwide outside of reached almost 40% last year! more about methodology
Until now, the FDA has never fined a single entity for failing to report results to , as required by law - despite thousands of violations by Pharma cos.
Are you searching for clinical trials that test new medical products or changes to a behavior? NLM's ClinicalTrials database provides information on privately and publicly funded clinical trials around the globe.
For more information, including eligibility criteria, on IRONMAN (An International Registry to Improve Outcomes in Men With Advanced Prostate Cancer) visit
$amrn Woukd be nice if reduce-it trial results were posted at but looks like Amarin requested an extension in June.
MOUNTAINEER: A Phase II, Open Label Study of Tucatinib + Trastuzumab in Patients With HER2+ Metastatic Colorectal Cancer #crcsm #camoldx WISN 12 News #NCT03043313
T3b. You learn you have to be an advocate for yourself. I now tell ppl to check out to see what is out there #gyncsm
v2.4.0 rolling out now: a check for preregistration from 5 registries. For and ISRCTN, you will see whether it is prospectively or retrospectively registered, and the primary & secondary outcomes right beside the paper
#EAonc E1Q11 EROS: Engendering Reproductive Health Within Oncologic Survivorship #SuppOnc #intonc Education Materials: #NCT01806129
No comparison. Under & limiting for US interventional trials, there are only 143 #gbm trials. Check out the options for #bcsm, #lcsm, & #pcsm. This is why one day isn’t enough!! #btsm #GBMday
For #SkinCancerAwarenessMonth, check out the #NCTN #melanoma trials S1320, S1512, S1607 and S1616, all actively accruing patients, led by . More information:
On your marks, get set, GO!💥#OMWaNATrial recruited our 1st baby 🎉Read about our research to improve #preterm outcomes here 👇Kangaroo Mother Care Before Stabilisation Amongst Low Birth Weight Neonates in Africa - Full Text View -
Can We Improve On via #ClinicalResearch #ClinicalTrials
This is a major issue for all the groups working on automated clinical trial matching and using as a source of truth.
, got it. If you go to , it is NCT 02884102. it is open at nearly all MMRC sites in US for RRMM patients to be sequenced #mmsm
#OHRP has just identified "two publicly available federal websites that will satisfy the consent form posting requirement" in the revised #CommonRule: and a docket folder on . More may be identified in the future.
the NCI opened up the code to (clunky & difficult to search) to developers... so cancer groups can customize it. CRC, & did just that for #CRCSM #ASCO19 abstract NCI:
In addition, the #NIH last week said it was delaying enforcement until September 2021 of the requirements for registering and reporting the results of basic experimental studies with humans on the agency's publicly available website, . #pharma #biotech
According to of speaking at #ATS2019 registration at skyrocketed once Journals started requiring it.
3. And this is a common problem. From Dr. : Only ~ half of #clinicaltrials over a sev yr period in w/ a rsrch biopsy related endpt reported results in a publication. Read more here: . #VailWorkshop19
Last chance to let NIH know that registration is problematic for behavioral studies! For instance, our stereotype threat studies would be affected by someone who reads a public preregistration and learns what the manipulation is.
In April 2018, 56% new advanced cell therapy trials are NOT registered on #clinicaltrials #celltherapy
HI RE: 11/2 " ⁦⁩ ⁦⁩ ⁦⁩ Lepto mets trial Mustang Bio. Thanks for your concern. City of Hope clarified that Mustang Bio is a Collaborator on the study record (NCT03696030) inquiries:[email protected]
The registered primary endpoint is change in burden (NCT00703157). The reported primary endpoint is freedom from AF? No mention of non-inferiority in the registration.
MOUNTAINEER: A Phase II, Open Label Study of Tucatinib + Trastuzumab in Patients With HER2+ Metastatic Colorectal Cancer #crcsm #camoldx WISN 12 News #NCT03043313
Additional details on the #DoraTrial testing radium-223 with docetaxel in patients with prostate cancer can be found on
Journalists: Become a PubMed, , and stats guru. Apply for 's AHCJ-NLM Health Journalism Fellowship. Deadline 3/21.
On a happy note, I now have two open clinical trials on ! ! We have clinical trials!
Wondering where to post informed consent forms for NIH-funded clinical trials? Read our post for details on how to upload to either or
Taking a moment to mark the passing of Dr. Donald A.B. Lindberg, Director of the National Library of Medicine from 1984 to 2015. You may not recognize his name, but he helped change biomedical science w/ efforts like PubMed, , MedlinePlus, & more.
My first job as a practicing attorney started in 2007, when FDAAA was passed. I recall pharma being really afraid of $$$ penalties for noncompliance w/ requirements. The govt has let that fear dissolve completely, and given up an import enforcement tool.
ISSCR comments to FDA re proposed industry guidance relating to concern that rogue clinics offering #stemcell treatments are abusing the database to appear legitimate.
MOUNTAINEER: A Phase II, Open Label Study of Tucatinib + Trastuzumab in Patients With HER2+ Metastatic Colorectal Cancer #crcsm #camoldx WISN 12 News #NCT03043313
New #breastcancer clinical trial on Impact of Dietary Intervention on Tumor Immunity: the DigesT Trial
No one has the whole picture yet but at some point more info will enter the public domain. In the interim, we have published articles, listings, and so forth. High intubation rates in all HCMC publications about ketamine use in prehospital setting.
Researcher incentives and p-hacking in clinical trials: evidence from New DP by Adda, Decker & Ottaviani:
Registration on = representation of what’s available in study documents...not initially built envisioned as source for public information about trials. Process hasn’t transformed for multiple purposes (study protocol + public information) #healthlitrt
No requirement for phase 1 especially if not publishing or listed on . Investigators and institutions should have right to publish entire trial data if study closed to enrollment and >3 yrs pass. But contracting, particularly with CROs is fragmented
Know anyone who'd want to do a review of power calcs in trials? With and protocol registration, it would be possible now. My hunch is they're consistently optimistic.
query of for trials for treatment-refractory lymphoma (unmet need) --not easy #Lymsm
The funded “New onset diabetes” cohort (which will explore the relationship between NOD & #PancreaticCancer) is now on with a growing list of participating sites. #WorldDiabetesDay
BTW, HITM-SURE doesn’t mention $SRNE in the registration, but $SRNE advertises the trial as its own. The anti-CEA CAR T cell IP still belongs to my company and can only be legally licensed by my company (not or anyone else).
., were there at least 2 ketamine versus Midazolam for Prehospital Agitation studies with you as PI & just suspended by Hennepin Healthcare? The study listed on appears to differ from the study described in the Research Volunteer Handbook.
That said, I cared deeply about the ISCHEMIA trial. But had no idea about this fundamental change to the hypothesis. It wasn't ever put on (still not there).
There are many great clinical trials around the world for SMM. Would encourage you to seek out on #mmsm
"In a 20 September draft guidance statement, the FDA said that failure to register trials or submit results to the government database could result in fines of up to US$10,000 per day."
OSF Registries best way to check what’s been registered (). Currently connects to and In future will connect to or host more (like how connects and hosts many)
Holy fuck I just read the article. This is full-on dystopian stuff. WTAF? What is the number for this 'study'?
Anybody can post a trial on (i had no idea) — one of the many insights in this excellent piece about an exploitative area of medicine
Yes, trial registration means that high-level methods are typically available on or other registries () but protocol papers take many years to emerge ().
This point resonates with me. Stepping thru completed CLL / Lymphoma trials with QOL Results on So far, QOL elements assessed and reported uneven/disappointing. RWD could never be informative in respect to QOL, which is integral to assessing efficacy.
Don't forget that industry is better at reporting to
Stereotactic Radiation and Immunotherapy in Patients With Advanced Triple Negative Breast Cancer - Full Text View - via thanks
New #breastcancer clinical trial on ONC201 in Recurrent/Refractory Metastatic Breast Cancer and Advanced Endometrial Carcinoma
Did you know released a beta version for testing a few days ago? Feedback wanted: #AllTrials
registries aren't entered by the NIH investigators. It's unclear why the registry doesn't show the pre-specified primary aims from original protocol (see below) which were accurately reported here: and
Shouldn't it show up on etc if they changed it? and I are really hoping #ISCHEMIA is positive. Then we can have a calm debate on #ORBITA without anyone getting anxious about their $. $ anxiety has a lot to answer for.
Unapproved stem-cell treatments touted on federal database , study says - The Washington Post
This happens more than you know, . There need to be consequences for failing to disclose a commercial collaborator in . $MBIO
New question! How time consuming is it to register a clinical trial (simple psychosocial intervention) at
So "almost half" went to a distributor who took no risk, spent no development money, and basically served as a distribution intermediary? And the company that developed the drug, including 585 listed studies, took "more than half"?
Our #Immunotherapy study is open to GU #rareCA including #renalmedullary & #penilecancer
The lepto mets trial is a Mustang Bio trial, but Mustang isn’t mentioned anywhere on the page. needs to crack down on this deceptive practice.
A6.2 Patients can also visit this clinical trial finder: #PancChat
Another example of being abused. Ophthalmologist PI for "stem cell spinal cord injury study"
T3 // many people head to and it's improved, but much still to be done. How abt a patient-clinician joint brainstorm on this one?! #btsm
Today, I learned uses #opendata from to help match patients to trials. #opengov
There are limitations though: up to 80% of studies on reported number of secondary outcomes inconsistently, and 20% reported the values of primary outcomes inconsistently (Hartung et al, 2014). 4/5
for new reporting requirements, uploading for trial protocols & stats plans coming soon
Differential access to clinical trials in high versus low income countries. Interesting analysis pulling from !
Are Stem Cell Companies Abusing | DNA Science Blog
No longer in beta, the new interface is definitely friendlier to all users. Check it out!
Here is the doc of BCIS IABP vs NoIABP in highrisk PCI. PEP-MACE at dc or 28 days. That is good. SEP- mortality at 6 months among others. Also good. Nothing about death at 51 months.
Here's the long slow grind of getting to Federal Rules for ! #BetsyNLM
should be re-designed to allow for post-trial feedback from participants.
#BMJresearch on a methodological approach for assessing uptake of core outcome sets using
I have a few thoughts in this article, although I don't think it's fair to call this a 'sex drug.' No publication of results in peer reviewed papers or , as of few days ago. Now that the label is out though... (1/2) via
Database updated automatically from API every 24 hours; appreciate not every trial listed on
remains imp info source - among trials that are unpublished, but complete/terminated, 33% & 57% report results #PRC8
.⁦⁩ patient advocates (whom I can personally attest are very medically savvy) describe their experience with navigating #swogonc #asco19 Cc: ⁦⁩ ⁦
Most who responded to question from about sharing individual participant data said they wouldn't: Zarin #PRC8
A number of things need to happen: have physician discussion of trials with pts be standard, education to lay community about trials in general, dispel misconceptions, patient friendly websites, manageable /search engines, etc. It’s such an impt problem!
Good points Stephen, but summaries suck. Major cancer trials "with results" in some cases list no baseline characteristics other than median age.
Cool! Informed consent document upload coming soon to #mlanet17
Thank you. Interesting how much lower QOL reporting is in lymphoma phase 3 studies based on my analysis of endpoint and results reporting. Concerning how largely useless (tower of Babel) QOL reporting seems to be. #lymsm
New #breastcancer clinical trial on Preoperative Accelerated Partial Breast Irradiation for Tr…
"Unapproved stem-cell treatments touted on federal database " By
helps, but requires patient to know lingo, and may generate LONG list of results w/no way to choose "best." #gyncsm
Q & A backgrounder with on "pay-to-participate" stem cell studies registered on .
...Concerningly, [email protected]_FDA and do present something of a barrier to transparency themselves here, as some information on whether a trial is "Applicable" is withheld by them, for reasons that are unclear. Nonetheless, we have worked around this...
A median of 100% of trials for approved drugs are generally registered. is the most comprehensive database
Known issues around unregistered trials aside, should all RCTs be registered in or are there other registries? If the latter, is there a consolidated database or a way of deduplicating searches? After what point were most trials registered?
Excited our first mem-NK cell trial (funded by LLS and Dunkin Donuts)about to open ⁩. Phase 1 Trial of CIML NK Cell Infusion for Myeloid Disease Relapse After Haplo HCT - Full Text View -
#EAonc E1Q11 EROS: Engendering Reproductive Health Within Oncologic Survivorship #SuppOnc #intonc - Chairs: Patel & Zaren Education Materials: #NCT01806129
Our latest paper looks at how fMRI studies have used when registering their analyses:
New #breastcancer clinical trial on Wide Margin vs. Narrow Margin in Postneoadjuvant Lumpectomy
is unhelpfully deleting some useful old data. We have found it, and used it, to do something good on our NEW BLOG FROM ME
Currently, it doesn't look like we have any review-level evidence in our Registry specific to your topic. We suggest you try searching and . Good luck with your search!
Would like this concept if done by NCI (tax payer funded for trust) and it included bio specimen correlates. * A Disease Registry of Patients With Mantle Cell Lymphoma - #lymsm
Hey #Forest Pharmaceuticals Inc, trial completed x 1.5 yrs. Why no results in
phase III #DORAStudy testing radium-223 with docetaxel in men with castration-resistant prostate cancer and bone metastases ( NCT03574571) is now enrolling patients at 10 sites:
New #breastcancer clinical trial on S1501 Carvedilol in Preventing Cardiac Toxicity in Patients With Metastatic HER-2-Positive Breast Cancer
The FDAAA TrialsTracker is... ALIVE! You can see every trial that goes overdue on , the day it goes overdue. This is BIG POTATOES.
T5: search for I/O clinical trials at (1) NCI database , (2) clinical trial finders offered by disease-specific advocacy groups, (3) Cancer Research Institute #LCSM
Thanks to & for examining problems with the inclusion of pay-to-participate stem cell studies on the website, . Clinics selling "stem cell treatments" on a DTC basis use the site as a marketing platform.
I love it when organizations share their reporting recipes. Kudos ! Nerd’s notes: How we did the data analysis via
A8. 1/. is a terrific search engine (think of it like Google just for research) that, in my opinion, has become a lot more user-friendly in the past year, for docs and patients alike. #PancChat
Companies charging patients to take part in clinical trials of dubious & sometimes dangerous therapies gain cred by registering their research on . explores the issue.
New rules go into effect for researchers funded by NIH. ...They have to register on a government-built website, share whatever they find, even if they don’t prove what they hoped; get trained up in modern clinical practices.
Trialists’ Intent to Share Individual Participant Data Zarin et al Although 36.2% of 25 551 trial records said yes or maybe, several reflected confusion
New #breastcancer clinical trial on Anti PD-1 Antibody With Radiation Therapy in Patients With HER2-negative Metastatic Breast Cancer
.: "What steps have been taken to ensure that the trials listed on are actually trials and not fee-for-service treatments or mere advertisements?" (The answer is no steps. None. Zip.) cc:
Discrepancies between recruitment status and actual #clinicaltrial status Study
.. how have PHE responded so far? They told the BBC these trials are already reported: "We are committed to transparency and have already published this data publicly in academic journals and online at ." ...
A9. allows you to search by disease type #pancchat
Does information from increase transparency and reduce bias? Results from a five-report case series -- seems like the answer is "No"?
Perlmutter: 900 pembro trials on . Largest clinical trial effort ever undertaken by any org. Just about done w monotherapy studies, most trials now in combos. Moving to earlier stages of disease. #LeeHood80
#BMTTandem18 Sadelain: >240 CAR-T trials listed in , >40 companies developing CAR therapies
I'm overwhelmed by , can't imagine how patients feel #bcsm
A Double-Blind Trial of Psilocybin-Assisted Treatment of Alcohol Dependence -
New #breastcancer clinical trial on RAD 1802: Pilot Trial of LINAC Based Stereotactic Body Radiotherapy for Early Stage Breast Cancer Patients Eligible for Post-Operative Accelerated Partial Breast Irradiation (APBI)
New #breastcancer clinical trial on Copanlisib in Combination With T-DM1 in Pretreated Unresectable Locally Advanced or Metastatic HER2-positive Breast Cancer
$CELG down ~4% yesterday after this new DDI trial posted on raising concerns again on ozanimod re-filing timeline RBC confirmed with the company that this new study should not be rate-limiting for filing(rather for label expansion)
New #breastcancer clinical trial on Pilot Study Evaluating a Perioperative E-follow-up Pro…
Recurrent theme on how difficult it is to enroll patients on trial. and now have VA specific lists or filters. #AVAHO18
New #breastcancer clinical trial on To Reduce the Use of Chemotherapy in Elderly Patients With ER-positive and HER2-positive Breast Cancer (TOUCH)
New #breastcancer clinical trial on Effect of Pembrolizumab and Cisplatin on Metastatic, Locally Recurrent or Inoperable Triple-Negative Breast Cancer
New #breastcancer clinical trial on ONC201 With and Without Methionine-Restricted Diet in Patients With Metastatic Triple Negative Breast Cancer
While registration of a published trial is good, a question to ask is what studies of this drug haven't been published? Many registered studies aren't published >8yrs after registration: #AGS18
If you build clinical trial matching services on top of - who is confirming sites are open/active/recruiting when presenting this info to patients? info is seriously out of date. #GIGO #SCOPE2019
Mandating grantees to share results of clinical trials on make science more open, more ethical, and smarter. Philosophically it makes sense, But some researchers are upset via #OpenScience
New #breastcancer clinical trial on Evaluating a Novel Web-based Intervention for Breast Cancer Survivors
New #breastcancer clinical trial on Effect of Resistance Training Variable Manipulation in Postmenopausal Breast Cancer Survivors.
New #breastcancer clinical trial on Effects of Green Coffee Extract Supplementation on Adropin, Irisin, Vaspine,Systemic Inflammation and Oxidative Stress in Breast Cancer Survivors
New #breastcancer clinical trial on A Study of Rucaparib Administered With Radiation in Patients With Triple Negative Breast Cancer With an Incomplete Response Following Chemotherapy
Are we using the same !???!!!!!!! #justsayin #PancChat
This 2014 interview I did with Director Zarin of is worth another read today & note my questions to her as much as her answers. Not much has improved in 5 years #stemcells #FDA #bioethics
The Watch the Spot Trial - Follow up lung nodules Fleischner criteria old en new:
$10K penalty, potentially per day? FDA on the road to civil penalties for those who break rules. How would this impact the sketchy stem cell clinic listings there? #stemcells #stemcell
This listing provides information concerning one of the 'ketamine' clinical studies conducted by Hennepin. , just to confirm, this is the study your organization has suspended pending review, right?
How to avoid common problems when using in research: 10 issues. States follow-on studies can be registered under different NCTs & "Responsible Party" is usually NDA holder (interesting, since trial sponsor & NDA holder often differ)
Mining . Lessons on #trial #design and #transparency from by . "[The] data help our drug discovery researchers identify unmet needs, interesting assets, and potential collaborators."
New #breastcancer clinical trial on Bioelectrical Impedance Utilization and Dietary Intake Relation in the Breast Cancer Related Lymphedema
No, a clinical trial registry should not use just honor system. Check out 2014 interview w/then Director Deborah Zarin. It was bad "aha!" moment on stem cell clinics & more #bioethics #stemcells
New #breastcancer clinical trial on Confirmatory Clinical Evaluation of Novilase® Laser Therapy for Focal Destruction of Malignant Breast Tumors
If you build clinical trial matching services on top of - who is confirming sites are open/active/recruiting when presenting this info to patients? info is seriously out of date. #GIGO #SCOPE2019
A Safety and Efficacy Study Evaluating CTX001 in Subjects With Severe #SickleCell Disease #CRISPR
This wouldn’t be the first time ”forgot” to add itself to the registration for a trial. #CARTcells
Over 240 CAR-T studies registered at . B #BMTTandem18
New #breastcancer clinical trial on Prospective Trial of Digital Breast Tomosynthesis (DBT) in Breast Cancer Screening.
how do we fix once and for all? We need more effort on this. #ClinicialTrials #UGH #ocepip18
New #breastcancer clinical trial on Genetic Study of CYP2D6 Enzyme and Therapeutic Drug Monitoring of Tamoxifen
Brilliant. found tons of useful info by digging through the archives of , not just the current data. So many trials don’t reach accrual goals! #AUA19
T2: To find a #clinicaltrial - there are a number of key resources. Your MD can help, as can a local research navigator. Search engines like or local institution websites can help too! #gyncsm
New #breastcancer clinical trial on Sentinel Lymph Node Procedure in Ipsilateral Invasive Breast Cancer Relapse
New #breastcancer clinical trial on Evaluating the Impact of Evidence-based Information About Mammography on Breast Cancer Screening Decisions
New #breastcancer clinical trial on Photoacoustic Imaging in Diagnosing Changes in Tumors in Participants With Breast Cancer, Sarcoma, Skin Cancer, or Soft Tissue Malignancy and Healthy Volunteers
New #breastcancer clinical trial on Prospective, Multicentric Study Evaluating the Surgical Treatment by Mastectomy With Immediate Prosthetic Breast Reconstruction in Patients With Breast Cancer and Receiving Adjuvant Therapy …
New #breastcancer clinical trial on Biological and Clinical Effects of Palbociclib With Ovarian Suppression and Letrozole in the Neoadjuvant Treatment of Breast Cancer
New #breastcancer clinical trial on EXERCISING TOGETHER© for Couples Coping With Cancer
New #breastcancer clinical trial on Effect of a Clinical Nutrition Intervention Program in Breast Cancer Patients During Antineoplastic Treatment
New #breastcancer clinical trial on Addressing Sexual Concerns in Breast Cancer: Patient Intervention Study
New #breastcancer clinical trial on CFI-400945 in Patients With Advanced/Metastatic Breast Cancer
New #breastcancer clinical trial on Autoantibodies in Breast Cancer Detection
New #breastcancer clinical trial on Open Label Trial Evaluating M7824 (Anti-PD-L1/TGF-Beta TRAP) in a Window Setting in Patients With Stage II-III HER2/Neu Positive (HER2+) Breast Cancer (BC)
New #breastcancer clinical trial on ROS1 Targeting With Crizotinib in Advanced E-cadherin Negative, ER Positive Lobular Breast Cancer or Diffuse Gastric Cancer Study
New #breastcancer clinical trial on KİNECT® - Video Games Based Physiotherapy Programme in Patients With Breast Cancer Surgery
New #breastcancer clinical trial on The Use of FES-PET Imaging as a Tool to Detect a Possible Reversion of Estrogen Receptor (ER)-α Status in Patients With Metastatic Breast Cancer HER2 + and ERα Neg Treated With Trastuzumab +…
New #breastcancer clinical trial on The ConnectedCancerCare Pilot Study (CCC)
New #breastcancer clinical trial on Prophylactic Use of PEG-rh-CSF in Medium-high Risk of FN in Chemotherapy of Breast Cancer
New #breastcancer clinical trial on Assessment of Sensory Gating, Attention, and Executive Control in Breast Cancer
New #breastcancer clinical trial on Automated Breast Ultrasound as an Adjunct to Screening Digital Breast Tomosynthesis
New #breastcancer clinical trial on Influence of Multidisciplinary Breast Tumor Board on Physician Decision
New #breastcancer clinical trial on Study to Investigate the Effect of AB-101 in Breast Cancer Survivors
New #breastcancer clinical trial on A Phase 1b Study of Pegylated Liposomal Doxorubicin and Pembrolizumab (Keytruda) in Endocrine-resistant Breast Cancer
New #breastcancer clinical trial on Lynparza Breast Cancer Clinical Experience Investigation
New #breastcancer clinical trial on Neoadjuvant Study of Pyrotinib in Combination With Trastuzumab in Patients With HER2 Positive Breast Cancer
New #breastcancer clinical trial on ATOP TRIAL: T-DM1 in HER2 Positive Breast Cancer
New #breastcancer clinical trial on Innovation in Mammography: Tomosynthesis Pathways
New #breastcancer clinical trial on Phase I-II Study of SBRT for Breast Cancer
New #breastcancer clinical trial on Gut Microbiome Effect on the Neoadjuvant Chemotherapy-induced Immunosurveillance in Triple Negative Breast Cancer
New #breastcancer clinical trial on A Study to Evaluate Safety, Tolerability and Efficacy of Eribulin Mesylate in Treating Adult Females With Locally Advanced or Metastatic Breast Cancer
New #breastcancer clinical trial on Women With Breast Cancer Undergoing Chemotherapy: Implications in Quality of Life
New #breastcancer clinical trial on ALEXANDRIA Study Egypt
New #breastcancer clinical trial on Accelerated Partial Breast Irradiation With IMRT in Early Breast Cancer
New #breastcancer clinical trial on Randomized Trial of Accelerated Partial Breast Irradiation
New #breastcancer clinical trial on Effects of Mediterranean Diet and Naltrexone/Bupropion Treatment in Obese Breast Cancer Patients
New #breastcancer clinical trial on A Pilot Study Examining Molecular and Clinical Effects of Aromatase Inhibitor Therapy on Skeletal Muscle Function in Early Stage Breast Cancer
"In some instances, the significance of [registration with ] was overstated, as in one campaign that linked to the website and stated that the procedure was ‘funded by the NIH’."
website was often referenced. "these links clearly implied support from the NIH, as with the claim that a clinic was ‘doing treatments approved by the National Institute [sic] of Health’"
"In some instances, the significance of [registration with ] was overstated, as in one campaign that linked to the website and stated that the procedure was ‘funded by the NIH’."
New #breastcancer clinical trial on Breast MRI for Neaodjuvant Chemotherapy Response Prediction and Evaluation in Breast Cancer
New #breastcancer clinical trial on Sentinel Lymph Node Biopsy in Breast Cancer Surgery Using ICG
New #breastcancer clinical trial on Apatinib in Neoadjuvant Therapy for Patients With Breast Cancer
New #breastcancer clinical trial on Supermicrosurgery for Breast Cancer Survivors With Lymphedema.
New #breastcancer clinical trial on M7824 and Eribulin Mesylate in Treating Participants With Metastatic Triple Negative Breast Cancer
New #breastcancer clinical trial on Stress and Immunity Breast Cancer Project
New #breastcancer clinical trial on Southeast Netherlands Advanced Metastatic Breast Cancer Registry
New #breastcancer clinical trial on Study to Evaluate the Effect of Bevacizumab in Metastatic Triple Negative Breast Cancer
New #breastcancer clinical trial on Evaluation of Ocoxin®-Viusid® in Breast Cancer
New #breastcancer clinical trial on The Effect of Yoga on Barriers to Occupational Engagement in African American Breast Cancer Survivors
New #breastcancer clinical trial on Changing Health Behaviors to Manage Chronic Conditions in Community-dwelling African American Breast Cancer Survivors
New #breastcancer clinical trial on Safety and Efficacy of Pegteograstim in Korean Breast Cancer Patients
New #breastcancer clinical trial on Efficacy and Safety of BGB-290 in the Treatment of Metastatic HER2-Negative Breast Cancer Patients With BRCA Mutation in China
"AMSS will be determined by the treating paramedic, who will undergo training as a research associate prior to commencement of the study." 🤔 listing for now-suspended Hennepin 'ketamine study.'
New #breastcancer clinical trial on Neoadjuvant Tamoxifen, Palbociclib, Avelumab in Estrogen Receptor Positive Breast Cancer
New #breastcancer clinical trial on A Pilot Multi-Institutional Study to Evaluate the Accuracy of a Breast Cancer Locator in Patients With Palpable Cancers
New #breastcancer clinical trial on Sexual Health and Rehabilitation After Ovarian Suppression Treatment
New #breastcancer clinical trial on Talking to Employers and Medical Staff About Breast Cancer Treatment and Your Job
New #breastcancer clinical trial on Moving on After Breast Cancer Plus- for Breast Cancer Survivors
New #breastcancer clinical trial on Light Emitting Diode for theTreatment of Genitourinary Syndrome of Menopause Associated With Breast Cancer Treatment
New #breastcancer clinical trial on 68Ga-RM2 PET/MRI in Imaging Patients With Estrogen Receptor-Positive Breast Cancer
New #breastcancer clinical trial on Evaluating and Following Breast Cancer Patients in a Better Way
New #breastcancer clinical trial on Docosahexaenoic Acid (DHA) for Women With Breast Cancer in the Neoadjuvant Setting
New #breastcancer clinical trial on Physical and Psychological Effects of Different Temperature-controlled Breast Prostheses on Patients With Breast Cancer
New #breastcancer clinical trial on Hypofractionated Irradiation At Regional Nodal Area for Breast Cancer Vs Existed Standard Treatment
New #breastcancer clinical trial on Unraveling KAdcyla Resistance In Human Epidermal Growth Factor Receptor 2(HER2) Positive Advanced Breast Cancer (KATIA)
Yep. Authors are cautious about what happens. But since we know people admit to p-hacking (and they didn't start for nothing), we can have priors about the mechanisms here.
New #breastcancer clinical trial on HERPET- A Novel PET Imaging Study of HER2 in Breast Cancer
New Features in PubMed Labs! . Among other features, secondary source databanks such as and/or Dryad are found under Associated Data label on the abstract page and as navigational aids.
New #breastcancer clinical trial on Every Day Counts: A Lifestyle Program for Women With Metastatic Breast Cancer
New #breastcancer clinical trial on Study of 2 Ribociclib Doses in Combination With Aromatase Inhibitors in Women With HR+, HER2- Advanced Breast Cancer
New #breastcancer clinical trial on ABCSG C08-Exercise II: Trial of Endurance Exercise Following Adjuvant Chemotherapy for Colorectal Cancer
New #breastcancer clinical trial on A Pilot Study of Tomographic Optical Breast Imaging (DBT-TOBI) to Monitor Response to Neoadjuvant Therapy
New #breastcancer clinical trial on Capecitabine in the Treatment of Breast Cancer With Low-hormone Receptor Expression After Neoadjuvant Chemotherapy
New #breastcancer clinical trial on Image-guided De-escalation of Neo-adjuvant Chemotherapy in HER2-positive Breast Cancer: the TRAIN-3 Study
New #breastcancer clinical trial on Durvalumab With Trastuzumab and Pertuzumab in HER2-Enriched Breast Cancer
New #breastcancer clinical trial on Palbociclib for HR Positive / HER2-negative Isolated Locoregional Recurrence of Breast Cancer
New #breastcancer clinical trial on Elevate! : An Elderly Breast Cancer Cohort Study
New #breastcancer clinical trial on Decisions of Young Women With Breast Cancer Regarding Fertility Preservation Before Cancer Treatment and Family Building After Treatment
New #breastcancer clinical trial on Evaluate the Clinical Benefit of a Post-operative Treatment Associating Radiotherapy + Nivolumab + Ipilimumab Versus Radiotherapy + Capecitabine for Triple Negative Breast Cancer Patients Wi…
New #breastcancer clinical trial on Neoadjuvant Letrozole and Palbociclib in Patients With Stage II-IIIB Breast Cancer, HR+, HER2 -
New #breastcancer clinical trial on Neo-RT: A Study Investigating Whether Changing the Sequence of Treatments (Starting Radiotherapy Followed by Hormone Therapy Before Surgery) is Feasible
New #breastcancer clinical trial on Evaluation of Orally Administered SAR439859 in Japanese Postmenopausal Patients With Advanced Breast Cancer
New #breastcancer clinical trial on Involvement of SK3 Calcium Channel in Taxane Neuropathy
New #breastcancer clinical trial on Circulating Osteocalcin-positive Cells in Breast Cancer Bone Metastasis
New #breastcancer clinical trial on Pre-operative Trial for Breast Cancer With Nivolumab in Combination With Novel IO
New #breastcancer clinical trial on Evaluating the Efficacy of Neratinib on Live Cell HER2 Signaling Transduction Analysis Positive Triple Negative Breast
could answer better. Not sure what "open" means -- could be CIRB approved. I don't see listed on so I doubt it is activated yet.
New #breastcancer clinical trial on Breast Cancer Women on Aromatase Inhibitors Treatment
New #breastcancer clinical trial on A Study to Compare Pertuzumab + Trastuzumab + Vinorelbine vs. Placebo + Trastuzumab + Docetaxel in Previously Untreated HER2-positive Metastatic Breast Cancer
Agree progress is slow, but even in weak form, helps detect mismatch between what was planned and what was done: I used this in my most recent blogpost on blood test for ASD
Well, NIH also brought us with no consequences for "post hoc pre-registration", and the Office for Research Integrity that was going to stamp out misconduct 😂, so I'm a bit skeptical for now. My bet is we'll see a raft of exceptions and lax enforcement.
New #breastcancer clinical trial on Study of Stereotactic Body Radiation Therapy (SBRT) in Patients With Cancers of the Breast and Lung
New #breastcancer clinical trial on Stereotactic Radiation and Nivolumab in the Management of Metastatic Breast Cancer Brain Metastases
New #breastcancer clinical trial on Investigating the Effectiveness of Stereotactic Body Radiotherapy (SBRT) in Addition to Standard of Care Treatment for Cancer That Has Spread Beyond the Original Site of Disease
New #breastcancer clinical trial on Enhancing Shared Decision-Making in Breast Cancer
If my hypothesis is right, then why is the Canadian site mentioned in the letter not mentioned in the article or the entry? I hope I'm wrong, since this is concerning. Looking forward to learning more.
New #breastcancer clinical trial on Copanlisib and Fulvestrant in Treating Postmenopausal Patients With ER+ and HER2- Metastatic Breast Cancer Progressing After Aromatase and CDK 4/6 Inhibitors Treatment
New #breastcancer clinical trial on Converting HR+ Breast Cancer Into an Individualized Vaccine
New #breastcancer clinical trial on Assessment of Current Biomarker Testing Practices for Common Solid Cancers in Precision Oncology in the Community Setting
New #breastcancer clinical trial on Combination of Talimogene Laherparepvec With Atezolizumab
The trial starts at 480mg/day of #letermovir after a loading dose in patients >40Kg. There is a provision for adjusting the dose I. The trial depending on PK results and efficacy. Details in
New #breastcancer clinical trial on Olaparib and Durvalumab to Treat Patients With Metastatic Triple Negative Breast Cancer
New #breastcancer clinical trial on A Study to Evaluate the Safety and Efficacy of Ipatasertib in Combination With Atezolizumab and Paclitaxel or Nab-Paclitaxel in Participants With Locally Advanced or Metastatic Triple-Negati…
New #breastcancer clinical trial on Study on the Progress of Breast Cancer Cases in Males and the Assessment of Relapse Risk
New #breastcancer clinical trial on Albumin-Bound Paclitaxel Followed by Epirubicin in Combination With Cyclophosphamide in Triple Negative Breast Cancer
New #breastcancer clinical trial on Albumin-Bound Paclitaxel Combined With Carboplatin as Neoadjuvant Chemotherapy in Luminal B/HER-2 Negative Breast Cancer
Rather scandalous how long this has taken to publish. Trial finished many months ago and results have been buried on . A positive result would have been published MUCH quicker!
New #breastcancer clinical trial on Prospective Cohort Study of Traditional Chinese Medicine for Survival of Patients With Early Breast Cancer
New #breastcancer clinical trial on A Prospective Evaluation of the Peri-operative Hypoxia in Breast Cancer
New #breastcancer clinical trial on Limited Versus No-limited Shoulder Movement in Breast Cancer Surgery
New #breastcancer clinical trial on Magseed Enabled Long-Term Localization of Axillary Lymph Nodes
New #breastcancer clinical trial on Diet Restriction and Exercise-induced Adaptations in Metastatic Breast Cancer
New #breastcancer clinical trial on Evaluation in the Treatment of Neuropathic Pain Post Breast Surgery
New #breastcancer clinical trial on A Proof of Concept, Window Trial of the IMmunological Effects of AveLumab and Aspirin in Triple-Negative Breast Cancer
New #breastcancer clinical trial on Trial With Eribulin or Eribulin+ Endocrine Therapy in Locally-recurrent or Metastatic Breast Cancer Patients
New #breastcancer clinical trial on Follow-up of Sequential Chemotherapy and Stimulation for Fertility Preservation in Young Patients With Breast Cancer
New #breastcancer clinical trial on Prognosis and Targeted Therapy Related Molecular Screening Program for Patients of Breast Cancer in China
New #breastcancer clinical trial on The Value of High-resolution Ultrasound in the Detection of Lymph Node Metastasis: a Proposal of NI-RADS
New #breastcancer clinical trial on Evaluation of Impact of Sandostatin® Injection Before Axillary Clearance on Lymphocele Formation
New #breastcancer clinical trial on Light-CT in the Diagnosis of Breast Tumor and Lymph Node
New #breastcancer clinical trial on Assessment of Feasibility and Acceptability of Personalized Breast Cancer Screening
New #breastcancer clinical trial on Informative Tools to Optimize Neoadjuvant Therapy in ER Positive, HER2 Negative Breast Cancers
New #breastcancer clinical trial on Minimally Invasive Biopsy Predicting Breast pCR After NAC for Breast Cancer
New #breastcancer clinical trial on 18F-ASIS PET/CT Imaging of Tissue Factor Expression In Patients With Primary and Metastastic Cancer
New #breastcancer clinical trial on A Home-Based Walking Program and rTMS in Helping Breast Cancer Survivors Get More Physical Activity
New #breastcancer clinical trial on BP-C1 Monotherapy in Patients With Metastatic Breast Cancer: Estimation of Optimal Duration of Treatment
New #breastcancer clinical trial on NIMBUS: A Phase II Study of Nivolumab Plus Ipilimumab in Metastatic Hypermutated HER2-negative Breast Cancer
New #breastcancer clinical trial on Persistant Organics Pollutants in Breast Cancer.
New #breastcancer clinical trial on Intratumoral TriMix Injections in Early Breast Cancer Patients
New #breastcancer clinical trial on One Week Versus Three Week in Adjuvant Radiotherapy in Breast Cancer
New #breastcancer clinical trial on Attenuating Cancer Treatment-related Toxicity in Oncology Patients With a Tailored Physical Exercise Program
New #breastcancer clinical trial on Intensity Modulated Radiation Therapy or 3-Dimensional Conformal Radiation Therapy in Treating Patients With Lymph-Node Positive Breast Cancer
New #breastcancer clinical trial on Clinical Value of Next Generation Sequencing in Endocrine Therapy for Advanced Hormone Receptor Positive/HER-2 Negative Breast Cancer
New #breastcancer clinical trial on Predictive Value of Progastrin Titer at Diagnosis and of Progastrin Kinetics During Treatment in Cancer Patients
New #breastcancer clinical trial on Pivotal Study in HER2 Negative, Locally Recurrent or Metastatic Breast Cancer
New #breastcancer clinical trial on Clinical Study of Xinmailong Injection on Reducing Cardiovascular Toxicity in Adjuvant Chemotherapy in Breast Cancer
New #breastcancer clinical trial on ARFI, VisR and DDAI Ultrasound for Improving Discrimination of Malignant and Unresponsive Breast Cancer
New #breastcancer clinical trial on Activity Program During Aromatase Inhibitor Therapy
New #breastcancer clinical trial on Acupuncture for Hot Flashes in Hormone Receptor-Positive Breast Cancer, a Randomized Controlled Trial
New #breastcancer clinical trial on Understanding and Addressing Patient and Provider Preferences Around Discussions of Cost of Breast Cancer Care
New #breastcancer clinical trial on Open-label Trial of Lasofoxifene vs. Fulvestrant in Advanced or Metastatic ER+/HER2− Breast Cancer With an ESR1 Mutation
New #breastcancer clinical trial on Acute Exercise Intervention in Reducing Breast Cancer Risk in Healthy Participants
New #breastcancer clinical trial on GENe EXpression After Regional or General ANesthesia in Patients Undergoing Breast Cancer Surgery
New #breastcancer clinical trial on Phase 3 Trial of Elacestrant vs. Standard of Care for the Treatment of Patients With ER+/HER2- Advanced Breast Cancer
New #breastcancer clinical trial on GDC-0084 in Combination With Trastuzumab for Patients With HER2-Positive Breast Cancer Brain Metastases
New #breastcancer clinical trial on Web-Based Decision Aid in Increasing Engagement in Surgery Decision Making in Participants With Newly Diagnosed Stage 0-III Breast Cancer
New #breastcancer clinical trial on Mini-AFTERc Intervention for Fear of Cancer Recurrence
New #breastcancer clinical trial on Trends of Mastectomy and Breast-Conserving Surgery in Female Breast Cancer Patients
New #breastcancer clinical trial on Tissue Acquisition and Genomics Analysis of Breast Cancer and Other Gynecologic Malignancies
New #breastcancer clinical trial on Named Patient Use Program to Provide Abemaciclib (LY2835219) for the Treatment of Metastatic Breast Cancer
New #breastcancer clinical trial on The Effect of Acupuncture for Insomnia in Breast Cancer Patients Undergoing Chemotherapy
New #breastcancer clinical trial on Adjuvant Endocrine Therapy in Early Stage Breast Cancer: Adherence and Clinical Outcome
New #breastcancer clinical trial on Open Label Immunotherapy Trial for Breast Cancer
., is this document the 'notification of enrollment' for your 'Ketamine versus Midazolam for Prehospital Agitation' study (NCT03554915) listed on & now suspended? This form is what was provided to enrolled study subjects?
This 'Notification of Enrollment Form' appears to be for the Hennepin Healthcare 'ketamine' study listed on & now suspended. , is this document what was provided to individuals enrolled in the study?
., is this document the EMS data collection form used in the 'Ketamine Versus Midazolam for Prehospital Agitation' study listed on Study Identifier is NCT03554915.
New #breastcancer clinical trial on Impact of Pegfilgrastim on Trastuzumab Anti-tumor Effect and ADCC in Operable HER2+ Breast Cancer Breast Cancer
New #breastcancer clinical trial on CFI-402257 in Combination With Paclitaxel in Patients With Advanced/Metastatic HER2-Negative Breast Cancer
New #breastcancer clinical trial on Monitoring Response to Neoadjuvant Chemotherapy in HER2 Negative Breast Cancer Using High-speed MR Spectroscopic Imaging
New #breastcancer clinical trial on Sensorimotor Rehabilitation Program in Improving Quality of Life in Patients With Early Stage Breast Cancer
New #breastcancer clinical trial on Impact of 5-fraction Stereotactic Partial Breast Irradiation and Whole Breast Irradiation on Cosmetic Outcome and Patient-reported Outcomes in Early-stage Breast Cancer
New #breastcancer clinical trial on Atezolizumab and Cobimetinib or Idasanutlin in Participants With Stage IV or Unresectable Recurrent Estrogen Receptor Positive Breast Cancer
Co-opting of by patient-funded studies in Lancet by Presidential Task Force on Unproven Therapies members including Weiss, Oikonomou,
New #breastcancer clinical trial on The Breast Cancer & Physical Activity Level (BC-PAL) Pilot Study
New #breastcancer clinical trial on Examining Bioactivity of PVSRIPO in Triple Negative Breast Cancer
You can query but will miss some of the foreign trials. Always direct any trial related questions to ; he maintains a database.
New #breastcancer clinical trial on Investigation of Anti-tumour Effect and Tolerability of the PARP Inhibitor 2X-121 in Patients With Metastatic Breast Cancer Selected by the 2X-121 DRP
New #breastcancer clinical trial on Nutritional Preferences and Product Accessibility in Oral Nutritional Supplements in Participants With Breast, Colorectal, Upper Gastrointestinal, or Prostate Cancer
New #breastcancer clinical trial on Study of Adagloxad Simolenin (OBI-822) and OBI-821 Versus Placebo Treatment for High Risk Early Stage Triple Negative Breast Cancer Patients (TNBC) Following Neoadjuvant or Adjuvant Chemotherapy.
New #breastcancer clinical trial on A Study of the Addition of Metronomic Capecitabine to Standard Adjuvant Therapy in High Risk HER2+ BC paTients
New #breastcancer clinical trial on Irinotecan for Advanced and Metastatic Breast Cancer
New #breastcancer clinical trial on GammaPod Registry and Quality of Life Nomogram
New #breastcancer clinical trial on A Study of ZN-c5 in Subjects With Breast Cancer
New #breastcancer clinical trial on Survey of Health Preferences in Cancer Patients (QALY-Cancer)
New #breastcancer clinical trial on A Biomarker Study of Palbociclib + Fulvestrant for Second, and Third Line of Postmenopausal Women With hr+/her2- Advanced Breast Cancer
New #breastcancer clinical trial on Efficacy of Magnetic Resonance-guided High Intensity Focused Ultrasound for the Ablation of Breast Cancer
Clinical trial design and dissemination: comprehensive analysis of and PubMed data since 2005 via
New #breastcancer clinical trial on A Study to Assess the Feasibility of an E-Health System (ZEMY) Designed to Manage Symptoms in Participants With Breast Cancer Under Anti-Cancer Treatment
New #breastcancer clinical trial on Artificial Intelligence vs Physicians for Breast Cancer Patients' Information
New #breastcancer clinical trial on Trial to Compare the Safety, Efficacy and Immunogenicity of TX05 With Herceptin® in HER2+ Early Breast Cancer
New #breastcancer clinical trial on Anti-hormonal Therapie With or Without Ribociclib in HR-positive / HER2- Negative Metastatic Breast Cancer
New #breastcancer clinical trial on Sentinel Lymph Node Biopsy in Patients With Breast Cancer After Neoadjuvant Therapy
New #breastcancer clinical trial on USG PECS vs LIA for Breast Cancer Surgery
New #breastcancer clinical trial on Effects of Infrared Laser Moxibustion on Cancer-related Fatigue in Breast Cancer Patients
New #breastcancer clinical trial on QUILT-3.057: NANT Neoadjuvant Triple- Negative Breast Cancer (TNBC) Vaccine
New #breastcancer clinical trial on Talimogene Laherparepvec With Paclitaxel or Endocrine Therapy in Treating Participants With Metastatic, Unresectable, or Recurrent HER2- Negative Breast Cancer