Researchers have used gene-editing to track the cell-by-cell development of a mouse embryo.
Researchers have used gene-editing to track the cell-by-cell development of a mouse embryo.
Very important work! #CRISPR ‘barcodes’ map mammalian development in exquisite detail Full developmental lineage record for every single cell in real-time
BTW I am blown away by this paper and its implications. Here is commentary by
CRISPR ‘barcodes’ map mammalian development in exquisite detail | original paper
Fascinating study that will likely have have a major impact on understanding human development and disease => CRISPR ‘barcodes’ map a mammalian development in equisite details
#CRISPR ‘barcodes’ map mammalian development in exquisite detail #Genomeediting technique enables researchers to trace lineage of cells in developing mice.
Lovely interview with on the use of CRISPR ‘barcodes’ to map mammalian development in exquisite detail
2/ And here we go... CRISPR ‘barcodes’ map mammalian development in exquisite detail
Fascinating story of the combo of reading and writing DNA to track cellular lineage through murine development. CRISPR barcoding and single cell sequencing will go even farther in developing a complete 4D developmental map at the cellular level.
From zebra fish to mammalian cells : another fascinating use of CRISPR technology
'Barcoding' cells across development can create a lineage of cell division in mammals. Just think of the insights this will bring down the research road for understanding human development. I. Can't. Wait.