New today! The Epi25 Collaborative explore genetic variation across epilepsies, finding an excess of ultra-rare, deleterious variants in constrained genes & in genes previously associated with epilepsy
Ultra-Rare Genetic Variation in the Epilepsies: A Whole-Exome Sequencing Study of 17,606 Individuals - strong evidence for involvement of ultra-rare mutations, but gonna need bigger samples to identify individual culprits