Assessment of Polygenic Architecture and Risk Prediction based on Common Variants Across Fourteen Cancers
bioRxiv 10d 4 tweets
We analyzed summary-level data from genome-wide association studies (GWAS) of European ancestry across fourteen cancer sites to estimate the number of common susceptibility variants (polygenicity) contributing to risk, as well as the distribution of...


Nilanjan Chatterjee 9d ago
A large collaborative effort to compare polygenic architecture across 14 cancers n utility of PRS for prediction
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bioRxiv Genetics 10d ago
Assessment of Polygenic Architecture and Risk Prediction based on Common Variants Across Fourteen Cancers #biorxiv_genetic
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GWAS_lit 10d ago
Assessment of Polygenic Architecture and Risk Prediction based on Common Variants Across Fourteen Cancers
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Eric Topol 9d ago
"We show that polygenic risk scores have substantial potential for risk stratification for relatively common cancers such as breast, prostate and colon." Analysis of common genomic variants for 14 types of #cancer, by Yan Zhang et al
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