More evidence that neoadjuvant chemo in cervix cancer is not the answer. Worse PFS and OS when you delay definitive chemoradiotherapy by giving neoadjuvant chemo. Hopefully OUTBACK shows that we can reduce distant failure with adjuvant chemo.
Addition of neoadjuvant cisplatin/gemcitabine to standard chemoradiation for locally advanced cervical cancer does not improve outcomes #gyncsm
Neoadjuvant chemotherapy was associated with lower response rates and survival compared with radiation and chemosensitization for locally advanced #cervicalcancer: A Randomized Phase II Trial. #gyncsm