Our latest paper in shows that even high doses of fluconazole lead to resistance in Cryptococcosis when used alone- but it's the ONLY drug available to many patients in Africa. Access to flucytosine is needed!
#Fluconazole Monotherapy Is a Suboptimal Option for Initial Treatment of #Cryptococcal Meningitis Because of Emergence of Resistance William Hope, , and colleagues in
Cryptococcal meningitis is a leading cause of death among adults with #AIDS and fluconazole is the only agent available for treatment in many settings. A study found that #AntimicrobialResistance is linked with the current recommended dosage.