Transcription phenotypes of pancreatic cancer are driven by genomic events during tumor evolution (Chan-Seng-Yue et al.)
Very interesting new paper on pancreatic cancer! For several years the debate has been on how many subtypes of PDAC there are. The field seems to have settled on two major transcriptional subtypes (classical, basal). But what drives these phenotypes...
Congratulations to the authors for this huge effort published ⁦⁩, which undoubtedly will be a framework for future therapeutic development. #cancer #PancreaticCancer #CancerResearch #nature #science