An update on the latest hydroxychloroquine results. We need more and better data, but what's out now is definitely not as encouraging as it could be
My "go to" for drug effects is . Today he summarized the latest data on this controversy "statistically, it's like a funhouse mirror" Cliff notes here:
Apr 6, 2020 SWEDEN Swedish hospitals are reporting that they have stopped administering #hydroxychloroquine and the HCQ/AZ combination due to lack of evidence & concerns about adverse reactions. #TuesdayThoughts
Reading: 'Hydroxychloroquine Update For April 6' by in which he explains the relation between effect size and trial size and the parachute effect.
Studies are still not promising. #COVID19 Hydroxychloroquine Update For April 6 | In the Pipeline
. on hydroxychloroquine: “Over and over there have been what looked like positive results that evaporated on closer inspection. […] the only way to be sure [… is to run] powered controlled trials. No shortcuts, no gut feelings – just data.”
So many drugs in development LOOK like they're going to work, but don't. has the scars to prove it: #datanotfeelings
More sober-minded assessment of the possible efficacy of chloroquine for COVID19 via We could easily harm people by using this drug on a wide scale.
For a smart, startling window into scientific debate/anger/politics of non-peer-reviewed data check out the writing and reactions on #COVID19 #Hydroxychloroquine use here
A roundup of the latest hydroxychloroquine trials for Covid 19. With the usual caveats (small trials, not much data), the signs don’t look too promising
If you are wondering: Hydroxychloroquine Update For April 6 | In the Pipeline
In the Pipeline is reviewing #covid19 clinical studies > "over and over there have been what looked like positive results [for other diseases] that evaporated on closer inspection. After you’ve experienced this a few times, you take the lesson to heart"
When treatment decisions are based in limited experiences that could be biased, then many unanswered questions arise and until now we have no evidence based treatment guidelines #OncoAlert Hydroxychloroquine Update For April 6 | In the Pipeline
Well informed commentary here
A more careful view of the malaria drug protocol based on #science
From "Science Translational Medicine" - a slightly better source than Peter Navarro. I'm sure Trump will read this carefully.
A nice summary of what we know so far. In 6 days my guess for a successful RCT on ChQ / HCQ will be wrong 🤕
to all those panic buying Hydroxychloroquine: first read 's razor sharp dissection of where we stand vs. #COVIDー19