Neuropilin-1 facilitates SARS-CoV-2 cell entry and provides a possible pathway into the central nervous system
bioRxiv 268d 3 tweets
The causative agent of the current pandemic and coronavirus disease 2019 (COVID-19) is the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Understanding how SARS-CoV-2 enters and spreads within human organs is crucial for developing...


Yohei Yamauchi 268d ago
Two independent studies showing #COVID19 uses its furin-cleaved S1 CendR (sender) motif to hijack cell surface Neuropilin-1 in order to (1) facilitate host cell entry and (2) enhance viral spread to the CNS.
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Institute of Biotech 265d ago
Coronavirus research updates: Virus conscripts a pair of human proteins to invade cells. Check out the full preprint at #COVID19Pandemic
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Peter J. Cullen 268d ago
An exciting paper . Independent evidence proposing a role for NRP1 in SARS-CoV-2 infectivity .
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