Spain's seroprevalence study #ENECOVID is out #SARSCoV2 IgG antibodies: 5% nationwide, 11% in Madrid Lower % in children 1/3 of asymptomatic infections A logistics feat with >60,000 participants This is what a highly engaged citizenry can do
New paper out in about seroprevalence of COVID antibodies in Spain. Here's the paper: It tells us some important things: First, proportion of folks who've been infected in Spain, one of the hardest hit places in Europe, is about 5% Thread
New : a seroprevalence study of over 60,000 people in Spain. 5% with marked geographic heterogeneity. 33% infections were asymptomatic and few (pauci-) were categorized by Marina Pollan and colleagues
NEW—First nationwide population-based study presents seroprevalence estimates of antibodies against SARS-CoV-2 at national and regional levels, exploring the landscape of population immunity in Spain (#ENECOVID)
What share of Spain’s population has antibodies for the new coronavirus? Even in Spain – one of the very worst-hit countries so far – only 5% have antibodies. The big (sample 61k) serological study of Spain is now published in The Lancet
Here’s the full paper in . Biggest serological survey yet published (61K+ people). Only ~5% had COVID antibodies. 95% of people in Spain still susceptible, despite one of Europe’s most intense outbreaks.
JUST IN: Prevalence of SARS-CoV-2 in Spain: a nationwide, population-based seroepidemiological study of 60k people #COVID19 in : only 5% seropositivity
Nationwide population-based study in Spain shows only 5% seroprevalence. I don’t think this represents the true proportion of population that is 𝙣𝙤𝙩 susceptible. Spain could not have controlled COVID if true herd immunity now is only 5%. 1/
Spain's SARS-CoV-2 prevalence is just ~5% despite one of Europe's largest #covid19 epidemics, from study today in . This is largest serological survey published to date & should give even further pause to the pursuit of "herd immunity". (1/2)
A Spanish #COVID19 serosurvey demonstrated that ~5% of the population has antibodies. "The majority of the Spanish population is seronegative to SARS-CoV-2 infection, even in hotspot areas" Still a long way from herd immunity. We need a vaccine. Pronto.
El estudio de prevalencia que hizo España es fantástico. Apenas existen otros a nivel nacional y —lo más importante— con una muestra aleatorizada (y por tanto representativa). Hoy The Lancet publica los detalles
Hotspots of #COVID19 in Spain have <10% population antibody levels. So: "In light of these findings, any proposed approach to achieve herd immunity through natural infection is not only highly unethical, but also unachievable." and
2) “Most PCR-confirmed cases have detectable antibodies, but a substantial proportion of people with symptoms compatible with COVID-19 did not have a PCR test and at least a third of infections determined by serology were asymptomatic.“
We are far from herd immunity. Spanish study in ⁦⁩ shows majority of population is seronegative to SARS-CoV-2 infection, even in hotspot areas. Need to continue public health measures to prevent/contain #COVID19 #SocialDistancing #Masks4All
🦠Spain's #seroprevalence study #ENECOVID is out #SARSCoV2: 🔹IgG #antibodies: 5% nationwide, 11% in Madrid 🔹Lower % in children 🔹1/3 of asymptomatic infections 🔹>60,000 participants 🔗 #COVIDー19 #SEMITuit
Large scale study in Spain: only 5% develop antibodies. Interview on ABC now “Trying for herd immunity is unethical.. too many deaths”
Largest random #COVID19 seroprevalence study in Europe of >61,000 ppl from Spain. 5% with IgG abs. 1 in 3 asymptomatic. "Despite the high impact of COVID-19 in Spain, prevalence estimates remain low and are clearly insufficient to provide herd immunity."
Important study in today: after all Spain has been through, only 5% have antibody evidence of infection. Concludes: "Herd immunity...cannot be achieved without accepting many deaths & overburdening of health systems."
(1/6) Study of #SARSCoV2 antibody prevalence in 61,075 randomly sampled people in #Spain between 27 April and 11 May. Suggests 3.7% of population exposed (based on two positive antibody tests), higher in Barcelona (5.9%) and in Madrid (9.5%). #COVID19
It is hard to keep up with all of the information coming out in a pandemic. I try to highlight information that is important & credible. This article and its editorial are both. Read them and discuss them here. Article Editorial
New in ⁦⁩> Prevalence of #SARSCoV2 in Spain (ENE-COVID): a nationwide, population-based seroepidemiological study #COVID19
#HerdImmunity for #COVID19 is a nice fantasy. #VaccinesWork Prevalence of SARS-CoV-2 in Spain (ENE-COVID): a nationwide, population-based seroepidemiological study
Seroprevalence of SARS-CoV-2 in Spain was between 3.7% and 6.2%. A nationwide, population-based seroepidemiological study model has 8.6%
Massive serosurvey from Spain shows prevalences 10-13% in central Spain/Madrid. In contrast, NYC has seroprevalence 2x higher.
From the study out of Spain. "Despite the high impact of COVID-19 in Spain, prevalence estimates remain low and are clearly insufficient to provide herd immunity." Full article below
A key parameter for our model is the relative rate of infection for children compared to adults. We calibrate the model so that children are 2/3 as likely to be infected, consistent with this large-scale seroprevalence study from Spain. 6/N
Nice study, 5-6x, more seropositivity than known PCR positives, sounds more realistic to me than other studies. Prevalence of SARS-CoV-2 in Spain (ENE-COVID): a nationwide, population-based seroepidemiological study
The study is now out in the Lancet. Highlights: 1) As noted above, 5% seropositive and far from herd immunity even in hotspots 2) Roughly 1/3 of infections were asymptomatic.
"In light of these findings, any proposed approach to achieve herd immunity through natural infection is not only highly unethical, but also unachievable ... (we) can quickly return to early pandemic dimensions in a second wave once measures are lifted."
The majority of Spanish population - 95% - is seronegative to SARS-CoV-2 infection, even in hotspot areas. at least a third of infections determined by serology asymptomatic Results emphasise the need for public health measures to avoid new epidemic wave
Prevalence of SARS-CoV-2 in Spain (ENE-COVID): a nationwide, population-based seroepidemiological study finds that only 5% of the population in Spain had developed antibodies to the coronavirus, indicating that herd immunity is still far-off.
Prevalence of SARS-CoV-2 in Spain (ENE-COVID): a nationwide, population-based seroepidemiological study
Our serosurvey finally published as a scientific paper instead of a gov report
tested positive for IgC antibodies in a point-of-care test and 2% in an immunoassay; for symptomatic patients, the figure was 16.9% for both tests. See Table 2 here
for IgG antibodies in a point-of-care test and 2% in an immunoassay; for symptomatic patients, the figure was 16.9% for both tests. See Table 2 here.
Another interesting aspect of the study is the extent to which the seroprevalence varies based on the population characteristic: 90% in history of PCR positive COVID persons ~20% in persons with history of symptoms suggestive of COVID. 2/
Prevalence of #SARSCoV2 in Spain: Only about 5% had a positive IgG antibody test. Almost 90% of PCR+ve patients had the antibody >14 days after the PCR test #COVID19 #antibody
Prevalence of SARS-CoV-2 in Spain (ENE-COVID): a nationwide, population-based seroepidemiological study - The Lancet
Spain "Seroprevalence was 5·0% (95% CI 4·7–5·4) by the point-of-care test"
But this citation is completely bogus. The Lancet that surveyed seroprevalence levels in Spain - it's point was NOT that herd immunity wouldn't work for some immunological reason - but that too few people were infected for it to be relevant now.
Prevalence of SARS-CoV-2 in Spain (ENE-COVID): a nationwide, population-based seroepidemiological study