A new report: viral load in children vs adults + coverage by “It definitely shows that kids do have levels of virus similar to and maybe even higher than adults"— (not = transmissibility)
Children and #SARSCoV2 #COVID19, over & over again the same finding: No differences in viral loads #COVID19 - surprised these findings get rather little attention, when a few weeks ago media were obsessed with the topic (at least in Germany) via
(1/2) Study of viral load in symptomatic children and adults with #COVID19. Children aged 5-17 had similar viral load to adults, but young children (<5 years) had levels 10-100 times higher. May be high risk that symptomatic children will transmit virus.
2) Second, this one from Chicago and : Takeway: the level of the virus in kids is AT LEAST as high as the level of virus in adults.
I'm struggling to reconcile these new findings in —that young children have *higher* viral titres than adults—with the epidemiology of transmission from young children and my personal experience of preschoolers' hygienic practices.
Study shows kids < 5 y.o had 10- 100x higher levels of #SARSCoV2 RNA in their NP compared to older kids & adults. This is important b/c young kids may be important drivers of #SARSCoV2 in the population which may have implications for vaccine campaigns
#COVID19 Viral loads higher in children vs adults. New paper. Quick thread.
Age-Related Differences in Nasopharyngeal #SARSCoV2 Levels in Patients With Mild to Moderate COVID-19 via Children < 5 years old had 10- to 100-fold higher levels of SARS-CoV-2 RNA in their nasopharynx compared with older children and adults
Strong work from & Co. Age-Related Differences in Nasopharyngeal SARS-CoV-2 Levels in Patients With Mild to Moderate COVID-19 via part of
Maybe? Trying to reconcile with this
Age-Related Differences in Nasopharyngeal Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Levels in Patients With Mild to Moderate Coronavirus Disease 2019 (COVID-19) | Infectious Diseases have you seen ct < 10?
"we report that replication of SARS-CoV-2 in older children leads to similar levels of viral nucleic acid as adults, but significantly greater amounts of viral nucleic acid are detected in children younger than 5 years"
Age-Related Differences in Nasopharyngeal SARS-CoV-2 Levels in Patients With Mild to Moderate COVID-19
Not going to lie, the raw CT values of under 5 kids has me looking at my preschooler very suspiciously right now (CT values (6.5 [4.8-12.0]) in
Age-Related Differences in Nasopharyngeal Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Levels in Patients With Mild to Moderate Coronavirus Disease 2019 (COVID-19)
Age-Related Differences in Nasopharyngeal SARS-CoV-2 Levels in Patients With Mild to Moderate #COVID19 via part of
significantly greater amounts of viral nucleic acid are detected in children younger than 5 years."