Excited to be enrolled in a free @MIT class on coronavirus. Today's lecturer is David Baltimore of MIT and CalTechn. #Follow this thread for live tweets.
Epidemiologist @michaelmina_lab is giving a free online lecture through MIT about covid-19. The decline of covid-19 cases in the summer may have misled people into thinking it had gone away. It didn't. The decline may have shown the "seasonality" of virus. web.mit.edu/webcast/biolog…pic.twitter.com/09wMTFbR9E
The novel coronavirus makes way fewer mistakes when copying its genome than viruses such as HIV, so it has fewer mutations. Why? Because it has an excellent copy editor. In comparison, HIV mutates constantly b/c it can't fix its mistakes. #copyeditors
Michel Nussenzweig: "In theory, the T-cell is NOT going to be effective in preventing the infection." Antibodies do that. But T-cells can prevent severe disease. You may become reinfected with covid, but hopefully have less serious illness second time. web.mit.edu/webcast/biolog… 12/
LIVE: Epidemiologist @michaelmina_lab compares benefits/limitations of viral tests vs antibody tests. Testing for virus catches people while they're still transmitting, but will miss people. Good for surveillance when testing is frequent.
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LIVE: Epidemiologist @michaelmina_lab is doing a pilot study to test blood, looking for antibodies, to reconstruct introduction of virus into U.S. He asks, "Could we have early warning system for viruses like we have for hurricanes?"
web.mit.edu/webcast/biolog…pic.twitter.com/ZM60HnOmOf
@shivpilla gives us Immunology of COVID-19 for Beginners. The first immune cells to respond, when virus gets in the lung, belong to the innate immune system: neutrophils and macrophages, all-purpose fighters that arrives before antibodies are made.
It's really important to listen to people like Michel Nussenzweig on a regular basis, because it reminds us that most of us really know very little and should listen more, talk less. web.mit.edu/webcast/biolog… 9/ pic.twitter.com/7uLaCYURLH
LIVE: David Baltimore said he was surprised to look at this map and see that the novel coronavirus doesn't seem to be spreading effectively in Africa, with the exception South Africa, a more developed country.
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Epidemiologist @michaelmina_lab: Advantage of antibody testing for surveillance is that antibodies persist in your blood for at least months. So a test for the virus may turn negative once your body clears it; an antibody test would still be positive.