In a new study (), we have completely mapped mutations to #SARSCoV2 that escape human antibodies, and shown that these "escape maps" predict how virus evolves under antibody pressure & inform design of escape-resistant antibody cocktails. (1/12)
Do we need cocktails of antibodies rather than a monoclonal to take on the virus? The escape variants of #SARSCoV2 that could block a neutralizing antibody, extensively mapped Answer: it depends.
Complete mapping of mutations to the SARS-CoV-2 spike receptor-binding domain that escape antibody recognition via et al
Complete mapping of mutations to the SARS-CoV-2 spike receptor-binding domain that escape antibody recognition