To detect #COVID19 before it spreads to others, we need frequent accessible testing. We cannot detect pre/asymptomatic people before they spread if we do not test frequently. A new article in by ⁦⁩, Roy Parker and Me 1/x
With many treatments, we measure efficacy of a regimen, not just 1 dose. What if we reimagine COVID test sensitivity this way? In : repeated testing works like the layers of a COVID filter, stacking up to dx positives & break transmission chains.
We desperately need these rapid tests for infectious covid (not PCR for infected). The rationale and the obstacle (FDA) laid out so well by , , Roy Parker in today's
A new Perspective Rethinking #COVID19 Test Sensitivity — A Strategy for Containment.
Now the latest NEJM article (30 Sept) says why we need Rapid Antigen Tests and NOT a standard RT-PCR test. #SARSCoV2 #COVID19 Read the thread. [1] By several criteria, the benchmark standard PCR fails when used in a surveillance regimen.
Rethinking Covid-19 Test Sensitivity — A Strategy for Containment
Several recent appropriate critiques of this cheap, frequent, rapid-testing strategy advocated by , but I still strongly believe it's worth rolling out. Because right now for asymptomatic and pre-symptomatic transmission, we're clueless.
About three weeks ago, the country woke up to find that President Trump tested positive for COVID-19. Immediately people speculated about the source of infection --> a thread about how viral load info from PCR tests can inform public health responses. 1/x
Se necesitan test rápidos y baratos para la contención de casos. La PCR no es ideal para este fin (línea de abajo). El uso repetido de tests contrarresta su menor sensibilidad (línea de arriba). Necesitamos tests que midan infectividad, no tanto RNA.
A nice, succinct, to the point, article on viral kinetics, infections, testing, transmission and public health measures. @13pt for illustrations This illustration comes from a recent piece by us.
Yes. This. "rapid tests now need to be developed and approved for at-home use to enable true community-wide surveillance regimens for SARS-CoV-2."
To conclude, the evidence is mounting for the role of rapid antigen tests. These tests work to identify infectious people quickly, without delay. They are best used to identify infectious people when they are used frequently
Rethinking Covid-19 Test Sensitivity — A Strategy for Containment ⁦⁩ by ⁦
Etude/Il faut test tests rapides et pas chers pour limiter la propagation asymptomatique afin de tester très fréquemment - PLUSIEURS FOIS PAR SEMAINE! Allez Big Pharma Suisse !
Excellent perspective that clearly explains the need for repetitive point-of-care testing to detect infectious patients (instead of focusing on analyitical sensitivity) by
Rethinking Covid-19 Test Sensitivity — A Strategy for Containment | NEJM
A perspective on widespread asymptomatic home antigen testing is out in NEJM. It clearly articulates the benefits. Ignores the risks. To me, the big issue is implying the FDA is hampered and couldn’t authorize testing under this indication. (1/2)
If the population is your patient any test that can help bring COVID-19 R0 below 1 should be considered. Fast and cheap would be good! This is not true for patient care where accuracy is needed. #COVID19 #TestAndTrace
“Frequent use of cheap, simple, rapid tests [will allow to identify those that will provide the best Covid filters], even if their analytic sensitivities are vastly inferior to those of benchmark tests. Such a regimen can help us stop #Covid19.”
Rethinking Covid-19 Test Sensitivity — A Strategy for Containment | Great perspective in ⁦⁩ by ⁦⁩ a rising star and ⁦⁩ graduate.
Rethinking Covid-19 Test Sensitivity: A Strategy for Containment via & &
In case you missed it: along with: It's time to start taking widespread frequent screening with cheap, rapid tests seriously as a potential strategy and to do some proper evaluation...
This is what I try to explain to all of my friends. Cheap, at-home rapid tests could end the pandemic tomorrow, let's make it happen!
This concept has been out here for awhile, but very nice to see it in NEJM.
Rethinking Covid-19 Test Sensitivity — A Strategy for Containment | NEJM