Evolutionary Arms Race between Virus and Host Drives Genetic Diversity in Bat Severe Acute Respiratory Syndrome-Related Coronavirus Spike Genes
Journal of Virology 107d 1 tweets
The Chinese horseshoe bat (Rhinolophus sinicus), reservoir host of severe acute respiratory syndrome coronavirus (SARS-CoV), carries many bat SARS-related CoVs (SARSr-CoVs) with high genetic diversity, particularly in the spike gene. Despite these...


Kristian G. Andersen 107d ago
Very interesting paper on the evolutionary arms race between ACE2 receptors in bats and SARS-like coronaviruses. Constant shuffling of key residues - which means every now and again you might end up with a 'perfect' fit (like SARS-CoV-2).
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