SARS-CoV-2 Nsp1 binds the ribosomal mRNA channel to inhibit translation

Nature Structural & Molecular Biology 139d 2 tweets

Cryo-EM structural analysis reveals the mechanism by which the SARS-CoV-2 protein Nsp1 inhibits global translation.

Our joint efforts in understanding the pirate skills of #SARSCoV2 Nsp1 to inhibit translation are now out by @SpringerNature in @NatureSMB. A great journey together with @The_Ban_Lab, @KathaSchub, @OMuhlemann, @ProfVolkerThiel, and @a__jomaa among others!

Virus Bioinformatics 109d ago

Suppression of host innate immune response by #SARCoV2 non-structural protein 1 #Nsp1. Paper co-authored by EVBC member @ProfVolkerThiel #COVID19 #coronavirus