Covid reinfection in a 25 year-old man in Nevada, as confirmed by virus genomic sequencing; 2nd infection more severe
Okay, new paper out in . Yes, this guy was reinfected. Yes, he got sicker the second time around. No, it doesn't mean that this is common or that reinfection leads to enhanced disease.
Lots of coverage of this case study of symptomatic reinfection with SARS-CoV-2 after short period of time in US (). But when interpreting, worth remembering this advice from early in the pandemic:
NEW—Study confirms first case of #COVID19 reinfection in the USA, indicating exposure to the virus may not translate to total immunity: finding from a case study from the University of Nevada
ICYMI, the case report of 25 yo man from Nevada who was reinfected and sick enough with second illness to require medical care. A wonderful commentary from to make sense of what we know about reinfections so far.
Important, crucial know how common & clinical syndrome in 1st & 2nd infection, immunology profile before, during & after both. Why long term follow up patients & cohorts so important.Still a new illness we will still be learning about 10 years from now
8) Meanwhile, the earlier 2nd case of reinfection from Reno Nevada now finally Lancet published. Study confirms first case of #COVID19 reinfection in the USA, indicating exposure to the virus may not translate to total immunity.
#Coronavirus Reinfection: 🧬1st infection: April (symptomatic) 🧬2nd infection: June (symptomatic*) *Required hospitalization, O₂ 🧬Two virus genomes differed by 11 nucleotides ▪️Case A: 4 variants not in case B ▪️Case B: 7 variants not in case A 👉
A case of reinfection. The second infection was symptomatically more severe than the first. Major implications on herd immunity.
There are so many things we don't yet know about #COVID19, *including* if being infected grants any lasting immunity. The US is seeing documented cases of reinfection, so be wary of any claims that having #COVID19 makes you immune.
New in > Genomic evidence for reinfection with #SARSCoV2: a case study #COVID19
Every day that #SARSCoV2 reinfection remains in case report territory, (which it still is), gives me optimism about durability of immune response. Conceivable that we could have seen thousands of reinfections by now e.g. in HCWs. We haven't. That's good.
Genomic evidence for reinfection with SARS-CoV-2: a case study [Oct 12, 2020] Tillett et al. #2019nCoV #COVID19 #CCC19 HT
"the patient was infected by SARS-CoV-2 on two separate occasions by a genetically distinct virus. Thus, previous exposure to SARS-CoV-2 might not guarantee total immunity in all cases."
Genomic evidence for reinfection with SARS-CoV-2: a case study
Here is another credible case of #COVID19 reinfection ~6 weeks after initial infection. In this case the 2nd infection was more severe. Still unclear how (un)common this is as there are only ~5 credible cases of reinfection documented to date.
Genomic evidence for reinfection with SARS-CoV-2: a case study Reading now this case of reinfection. Not the first (at least 22 documented cases worldwide) & not the last but a rare event. Relevant to vaccine development, herd immunity and Trump!
Same day Trump proclaims himself “immune," the Lancet is out with a study on "two instances of SARS-CoV-2 infection in the same individual.”
Genomic evidence for reinfection with SARS-CoV-2: a case study - The Lancet Infectious Diseases ⁦⁩ ⁦⁩ ⁦
Genomic evidence for reinfection with SARS-CoV-2: a case study via et al and
Genomic evidence for reinfection with SARS-CoV-2: a case study
Genomic evidence for reinfection with SARS-CoV-2: a case study [Oct 12, 2020] Tillett et al. #CCC19 All individuals, whether previously diagnosed w/ #COVID19 or not, should take identical precautions to avoid infection w/ #2019nCoV
22/ How long will immunity last? Still a great unknown. The credible reports of reinfection are so rare that they’re the exception that proves the rule – it seems super-likely that immunity will last for at least a year, for the vast majority of people.
Genomic evidence for reinfection with SARS-CoV-2: a case study [Oct 12, 2020] Tillett et al. #CCC19 All individuals, whether previously diagnosed w/ #COVID19 or not, should take identical precautions to avoid infection w/ #2019nCoV
Genomic evidence for reinfection with SARS-CoV-2: a case study [Oct 12, 2020] Tillett et al. #CCC19 All individuals, whether previously diagnosed w/ #COVID19 or not, should take identical precautions to avoid infection w/ #2019nCoV
Genomic evidence for reinfection with SARS-CoV-2: a case study [Oct 12, 2020] Tillett et al. #CCC19 All individuals, whether previously diagnosed w/ #COVID19 or not, should take identical precautions to avoid infection w/ #2019nCoV
Genomic evidence for reinfection with SARS-CoV-2: a case study #covid19 #genomics #sarscov2
Genomic evidence for reinfection with SARS-CoV-2: a case study
Genomic evidence for reinfection with SARS-CoV-2: a case study