Minigraph is a tool that builds a pangenome graph from multiple long-read assemblies to encode simple and complex SVs. It is now published in along with the proposal of the rGFA and GAF formats
rGFA, a reference graphical fragment assembly approach for modeling reference pangenome graphs, from , Feng, and . The implementation, minigraph, can generate a graph from 20 human genomes in under 3 hours.