Just published We've known #SARSCoV2 unique feature is cleavage of its muring polybasic site, but it's neuropilin (NRP1) binding that is key factor for its infectivity, a new potential target
Helping explain what makes #SARSCOV2 so capable of infecting human cells, researchers in two independent studies discovered that the virus’s spike protein recognizes and binds a protein on the human cell surface called neuropilin-1
Just published in Science!! + more. Great job!!! #Neuropilin #COVID19 "Neuropilin-1 is a host factor for SARS-CoV-2 infection"
1). Excited that our collaborative discovery of neuropilin-1 as a host factor for SARS-CoV-2 infection is in Science . Driven by great virology of Katja Klein in , supported by biochemistry from James Daly and Boris Simonetti in .
Helping explain what makes #SARSCOV2 so capable of infecting human cells, researchers in two independent studies discovered that the virus’s spike protein recognizes and binds a protein on the human cell surface called neuropilin-1
Two back-to-back papers in report Neuropilin-1, an axon guidance protein implicated in brain development & angiogenesis, facilitates #SARSCoV2 cell entry and infectivity.
Neuropilin-1 is a host factor for SARS-CoV-2 infection
Just published We've known #SARSCoV2 unique feature is cleavage of its furin polybasic site, but it's neuropilin (NRP1) binding that is key factor for its infectivity, a new potential target
#Neuropilin_1 is a host factor for #SARSCoV2_Infection | NRP1 Interacts with S1 and enhances infection | Yohei Yamauchi
Neuropilin-1 is a host factor for SARS-CoV-2 infection
#Neuropilin_1 is a host factor for #SARSCoV2_Infection | CendR binding of SARS-CoV-2 S1 with NRP1 | Yohei Yamauchi
Neuropilin-1 is a host factor for SARS-CoV-2 infection
#Neuropilin_1 is a host factor for #SARSCoV2_Infection | Selective inhibition of the S1-NRP1 interaction reduces infection | Yohei Yamauchi
Neuropilin-1 is a host factor for SARS-CoV-2 infection (an important new role for an old friend from neural development)