Remdesivir Metabolite GS-441524 Efficiently Inhibits SARS-CoV-2 Infection in Mouse Model
bioRxiv 89d 1 tweets
The outbreak of coronavirus disease 2019 (COVID-19) rapidly spreads across worldwide and becomes a global pandemic. Remdesivir is the only COVID-19 treatment approved by U.S. Food and Drug Administration (FDA); however, its effectiveness is still...


Muller Lab 89d ago
Remdesivir Metabolite GS-441524 Efficiently Inhibits SARS-CoV-2 Infection in Mouse Model First direct demonstration of direct efficacy of #GS441524 against #SARSCoV2 in a mouse model. Strong efficacy, minimal toxicity, despite less than ideal PK.
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