Genetic influences on cell type specific gene expression and splicing during neurogenesis elucidate regulatory mechanisms of brain traits

bioRxiv 90d 1 tweets

Interpretation of the function of non-coding risk loci for neuropsychiatric disorders and brain-relevant traits via gene expression and alternative splicing is mainly performed in bulk post-mortem adult tissue. However, genetic risk loci are...

Nil Aygun 90d ago

I am very excited to share our @jsteinlab recent work "Genetic influences on cell type specific gene expression and splicing during neurogenesis elucidate regulatory mechanisms of brain traits" @biorxivpreprint biorxiv.org/content/10.110… Many thanks to all contributing to this work!