Rick Adams
Psychiatrist & scientist at UCL, working on psychosis, brain imaging, computational models of the brain. Views were probably someone else's first.
Last synced from Twitter 6m ago
UCL Wellcome 4-year PhD in Mental Health Science
The UCL Wellcome 4-year PhD in Mental Health Science is an opportunity for students to train in a wide range of fields relevant to mental health research.
Neuro-computational account of arbitration between imitation and emulation during human observational learning
In observational learning (OL), organisms learn from observing the behavior of others. There are at least two distinct strategies for OL. Imitation involves learning to repeat the previous actions of other agents, while in emulation, learning...
Petition to Society for Neuroscience to Act on the Climate Crisis
October 31st, 2019.
TO: The Council of the Society for Neuroscience (SfN)
FROM: Members of SfN (current and recently active)
As members of SfN, we are proud of our society’s legacy of scientific excellence and leadership that was vividly on...
A circuit mechanism for irrationalities in decision-making and NMDA receptor hypofunction: behaviour, computational modelling, and pharmacology
Decision-making biases can be systematic features of normal behaviour, or deficits underlying neuropsychiatric symptoms. We used behavioural psychophysics, spiking-circuit modelling and pharmacological manipulations to explore decision-making biases...
Broadband Signal Rather than Frequency-Specific Rhythms Underlies Prediction Error in the Primate Auditory Cortex
Detection of statistical irregularities, measured as a prediction error response, is fundamental to the perceptual monitoring of the environment. We studied whether prediction error response is generated by neural oscillations or asynchronous...
Finding the imposter: brain connectivity of lesions causing delusional misidentifications
See McKay and Furl (doi:10.1093/aww323) for a scientific commentary on this article.How a focal brain injury can lead to Capgras Syndrome, the delusion that a f
Lesions causing hallucinations localize to one common brain network
Lesions causing hallucinations localize to one common brain network
Computational noise in reward-guided learning drives behavioral variability in volatile environments
Findling, Skvortsova et al. find that a large fraction of non-greedy decisions that humans make in volatile environments do not stem from exploration but from the limited precision of learning, and further identify its neurophysiological correlates.
Intensive DNA search yields 10 genes tied directly to schizophrenia
Rare genetic variants could point to new treatments for severe psychiatric disorder
Multiple associative structures created by reinforcement and incidental statistical learning mechanisms
Associative learning occurs through reinforcement mechanisms as well as incidentally through experience of statistical relationships. Here, the authors report that these two learning processes are associated with specialized anatomical regions that...
GABA-ergic dynamics in human frontotemporal networks confirmed by pharmaco-magnetoencephalography.
To bridge the gap between preclinical cellular models of disease and in vivo imaging of human cognitive network dynamics, there is a pressing need for informative biophysical models. Here we assess dynamic causal models (DCM) of cortical network...
A computational account of threat-related attentional bias
Author summary To make inferences and learn efficiently in the face of a multiplicity of stimuli we need to allocate attention preferentially to those that are most motivationally relevant. It is unclear how this is achieved in aversive...
Identification of neurobehavioural symptom groups based on shared brain mechanisms
Ing et al. develop a method of establishing direct relationships between psychiatric symptoms and neuroimaging measures of brain structure and function and use it to stratify adolescent psychopathology on the basis of underlying biology. They...
Reduced mu opioid receptor availability in schizophrenia revealed with [11C]-carfentanil positron emission tomographic Imaging
Post-mortem studies have suggested a possible reduction in mu-opioid receptor (MOR) density in people with schizophrenia. Here, the authors examined MOR in living patients with schizophrenia using PET imaging, and found local reductions of MOR...
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Rick Adams
@MBerkMirza @FarlKriston It is also highly relevant to ‘aberrant salience’ accounts of schizophrenia, but that’s another story... Congrats @MBerkMirza!
PS if you like the sofa in tweet 6 (it is extremely comfy), it is from makerandson.com
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Vacancy - PhD candidate ‘Predicting resilience and recurrence in major depressive disorder using machine learning based normative models.’
Job description: We are searching for a talented PhD candidate to work on a translational project bridging the gap between machine learning, ...
UCL awarded first Wellcome funded PhD programme focused on mental health
UCL has been awarded funding for a brand new PhD programme in Mental Health Science by the Wellcome Trust
Predicting individual clinical trajectories of depression with generative embedding
Patients with major depressive disorder (MDD) show heterogeneous treatment response and highly variable clinical trajectories: while some patients experience swift and enduring recovery, others show relapsing-remitting or chronic disease course....