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Why You Shouldn’t Worry About Studies Showing Waning Coronavirus Antibodies
Experts say it’s normal for levels of antibodies to drop after clearing an infection, and that they represent just one arm of the immune response against a virus.
Best practices for the analytical validation of clinical whole-genome sequencing intended for the diagnosis of germline disease
Whole-genome sequencing (WGS) has shown promise in becoming a first-tier diagnostic test for patients with rare genetic disorders; however, standards addressing the definition and deployment practice of a best-in-class test are lacking. To address...
euan ashley
New paper from our Medical Genome Initiative!
86d
Dozens to be deliberately infected with coronavirus in UK ‘human challenge’ trials
Proponents of the trials say they can be run safely and help to identify effective vaccines, but others have questioned their value.
Taiwan’s Digital Minister Knows How to Crush Covid-19: Trust
On day three of WIRED25, Audrey Tang explains how the Asian nation used open data and transparent governance to empower its citizens to code their own way out of a pandemic.
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euan ashley
It really could have gone another way. wired.com/story/wired25-… pic.twitter.com/gn4teO3kpL
92d
The two months in 1980 that shaped the future of biotech - STAT
Five events in a two-month span in 1980 propelled the nascent biotech industry and university biotech research into the future.
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euan ashley
Great writing, from @HankGreelyLSJU
The two months in 1980 that shaped the future of biotech
92d
Vagelos Receives First Master Clinician Award
Randall H. Vagelos, MD, is the inaugural recipient of the Department of Medicine’s Master Clinician Award.
euan ashley
So excited to see Randy Vagelos receive this award. He has mentored and inspired a generation of cardiology fellows and faculty.
96d
New deep learning models: Fewer neurons, more intelligence — SCIENMAG
Artificial intelligence (AI) can become more efficient and reliable if it is made to mimic biological models; new approaches in AI research are hugely successful in experiments
Scientists Confirm Nevada Man Was Infected Twice With Coronavirus
It's the first confirmed case of coronavirus reinfection in the U.S. The case underscores that everyone should be social distancing and wearing masks, including COVID-19 survivors.
A Network of Macrophages Supports Mitochondrial Homeostasis in the Heart
A system of macrophages in the heart supports cardiomyocyte health by phagocytosing
exopher particles ejected from cardiomyocytes that contain defective mitochondria,
among other cellular contents.
euan ashley
This is kinda amazing. (h/t @StearnsLab)
A Network of Macrophages Supports Mitochondrial Homeostasis in the Heart: Cell
98d
Scotland one win away from Euro 2020 but still the doubters remain
Though Scotland lacked ambition and attacking fluency in the penalty shootout win over Israel, Steve Clarke’s men are unbeaten in six games and showed admirable team spirit
euan ashley
Scotland one win away from Euro 2020 but still the doubters remain
"The latest clash with Israel was the definition of tedium for 120 minutes and yet..."
101d
Hold Me, Squeeze Me, Bite My Head
Two recent research efforts looked into the southern alligator lizard, which has one of nature’s more extreme mating strategies.
Rat That Sniffs Out Land Mines Receives Award for Bravery
Magawa, a 5-year-old African giant pouched rat, was recognized with a prestigious honor for his work detecting mines and explosives in Cambodia.
Characterization of clinically relevant copy-number variants from exomes of patients with inherited heart disease and unexplained sudden cardiac death
Copy-number variant (CNV) analysis is increasingly performed in genetic diagnostics. We leveraged recent gene curation efforts and technical standards for interpretation and reporting of CNVs to characterize clinically relevant CNVs in patients with...
euan ashley
Great work moving this field forward. Will be interesting to see what long reads uncover next.
115d
The (near) complete sequence of a human genome
The Telomere-to-Telomere (T2T) consortium is proud to announce our v1.0 assembly of a complete human genome. This post briefly summarizes our work over the past year, including a month-long virtual workshop in June, as we strove to complete as many...
Death Toll From Covid-19 Pandemic Extends Far Beyond Virus Victims
Researchers are finding growing evidence that the Covid-19 pandemic’s deadly reach is stretching far beyond people who died from coronavirus infections, reflecting the ways the pandemic amplified stress and financial strain while causing many people...
What Your Blood Tells You About Cancer
A drop of blood can reveal a lot about a cancer, and two recently approved tests dramatically improve cancer treatment
'Landmark moment': 156 countries agree to Covid vaccine allocation deal
Covax plan will counter rising threat of ‘vaccine nationalism’, prioritising vulnerable healthcare systems and frontline workers
The Vaccine Protocols
We now have the official clinical trial designs for the three biggest and most advanced coronavirus vaccine trials: Moderna, Pfizer/BioNTech and Oxford/AstraZeneca. Now, as for you, J&J, Novavax, Merck, and all the others that are pushing into...
SARS-CoV-2 Transmission Dynamics Should Inform Policy by Muge Cevik, Julia Marcus, Caroline Buckee, Tara Smith :: SSRN
It is generally agreed that striking a balance between resuming economic and social activities and keeping the effective reproductive number (R0) below 1 using