A special ceremony will mark the repatriation of over 200 manggu samples to their island home.
Matthew WakefieldI am extremely proud of the genomics community in Australia and particularly the NCIG for how they have handled this issue. “Indigenous blood samples return to Galiwin'ku after 50 years in medical storage”
The extensive generation of RNA sequencing (RNA-seq) data in the last decade has resulted in a myriad of specialized software for its analysis. Each software module typically targets a specific step within the analysis pipeline, making it necessary...
Matthew WakefieldARMOR: an Automated Reproducible MOdular workflow for preprocessing and differential analysis of RNA-seq data
The Australian government has ignored the expertise of researchers, developers, major tech companies, and civil liberties organizations by charging forward with a disastrous proposal to undermine trust and security for technology users around the...
The target profiles of many drugs are established early in their development and are not systematically revisited at the time of approval, raising the question whether human therapeutics with the same nominal targets but different chemical...
Matthew Wakefield"Multi-omics profiling establishes the polypharmacology of FDA Approved CDK4/6 inhibitors and its impact on drug response [NEW RESULTS]"
Melbourne is expanding at breakneck speed, and risks becoming a victim of its own popularity. Its inhabitants now face a choice between two population plans, and experts warn the consequences of getting it wrong will be dire.
Around 10% of high-grade serous ovarian carcinomas (HGSOC) harbor BRCA1 promoter methylation, but it is uncertain how it predicts response to PARP inhibition. Here, the authors show that homozygous BRCA1 methylation predicts response to rucaparib...
Scientific output is not a linear function of amounts of federal grant support to individual investigators. As funding per investigator increases beyond a certain point, productivity decreases. This study reports that such diminishing marginal...
Matthew WakefieldBigger grants means less papers and fewer citations. If you take papers as the output of science this is a bad thing. Alternatively it could be that our obsessive level of science publication is a drain on the enterprise the well off reduce.