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Florida reported 15,300 new COVID-19 cases Sunday, once again shattering its record for a single-day increase in cases. The state also broke its record for most tests administered in a day with 99,003 new tests reported.
An interbacterial toxin that catalyses the deamination of cytidines within double-stranded DNA forms part of a CRISPR-free, RNA-free base editing system that enables manipulation of human mitochondrial DNA.
Loss of function of Nav1.7 leads to congenital insensitivity to pain in humans. Here the authors found that activation of Nav1.9 can restore nociception in Nav1.7 knockout mice, revealed by a venom-derived peptide as a probe.