Kirstyn Brunker
Postdoc at University of Glasgow (she/her): Rabies | MinION | LabinaSuitcase | Disease Ecology and Control | Viral evolution #masterOfNone
Thought Leader
| #292 | Infectious Disease |
Last synced from Twitter 90d ago
Establishment & lineage dynamics of the SARS-CoV-2 epidemic in the UK
The UK's COVID-19 epidemic during early 2020 was one of world's largest and unusually well represented by virus genomic sampling. Here we reveal the fine-scale genetic lineage structure of this epidemic through analysis of 50,887 SARS-CoV-2 genomes,...
Lessons from applied large-scale pooling of 133,816 SARS-CoV-2 RT-PCR tests
Pooling multiple swab samples prior to RNA extraction and RT-PCR analysis was proposed as a strategy to reduce costs and increase throughput of SARS-CoV-2 tests. However, reports on practical large-scale group testing for SARS-CoV-2 have been scant....
Unlocking the efficiency of genomics laboratories with robotic liquid-handling
In research and clinical genomics laboratories today, sample preparation is the bottleneck of experiments, particularly when it comes to high-throughput next generation sequencing (NGS). More genomics laboratories are now considering liquid-handling...
Oxford scientists develop extremely rapid diagnostic test for Covid-19 | University of Oxford
Scientists from Oxford University’s Department of Physics have developed an extremely rapid diagnostic test that detects and identifies viruses in less than five minutes.
Psychedelic Porn Crumpets Announce New Album 'SHYGA! The Sunlight Mound'
Psychedelic Porn Crumpets will release new album 'SHYGA! The Sunlight Mound' on February 5th.…
Enabling animal rabies diagnostic in low-access areas: Sensitivity and specificity of a molecular diagnostic test from cerebral tissue dried on filter paper
Author summary Dogs are responsible for 99% of human rabies deaths. Facilitating diagnostic of rabid dogs can help further identify i) people who were exposed to rabies in order to encourage them to seek post exposure prophylaxis and ii) other...
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Kirstyn Brunker
#PLOSNTDs: Enabling animal rabies diagnostic in low-access areas: Sensitivity and specificity of a molecular ...
105d
The One With The Rabies Round Table
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Rabies
100% preventable viral disease, rabies is transmitted to humans through the infected dog bites. It is fatal once symptoms develop. Target is to reach zero human rabies deaths by 2030. #BeatNTDs
LamPORE evaluation study shows 99.1% sensitivity, 99.6% specificity
Scientists from the University of Oxford’s Nuffield Department of Medicine, Public Health England Porton Down (PHE), the University of Sheffield, Sheffield Teaching Hospitals NHS Foundation Trust have today published their evaluation of LamPORE,...
Why misinformation about COVID-19’s origins keeps going viral
Another piece of coronavirus misinformation is making the rounds. Here’s how to sift through the muck.
Predicting the presence and titre of rabies virus‐neutralizing antibodies from low‐volume serum samples in low‐containment facilities
Serology is a core component of the surveillance and management of viral zoonoses. Virus neutralization tests are a gold standard serological diagnostic, but requirements for large volumes of serum a...
Harnessing technology and portability to conduct molecular epidemiology of endemic pathogens in resource-limited settings
Abstract. Improvements in genetic and genomic technology have enabled field-deployable molecular laboratories and these have been deployed in a variety of epid
Development and Application of a Prophage Integrase Typing Scheme for Group B Streptococcus
Group B Streptococcus (GBS) is a gram-positive pathogen mainly affecting humans, cattle, and fishes. Mobile genetic elements play an important role in the evolution of GBS, its adaptation to host species and niches, and its pathogenicity. In...
Eurosurveillance | Geographical and temporal distribution of SARS-CoV-2 clades in the WHO European Region, January to June 2020
We show the distribution of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) genetic clades over time and between countries and outline potential genomic surveillance objectives. We applied three genomic nomenclature systems to all...
LamPORE: rapid, accurate and highly scalable molecular screening for SARS-CoV-2 infection, based on nanopore sequencing
LamPORE™ is a rapid way of testing/screening large numbers of samples for the presence or absence of SARS-CoV-2, the virus causing COVID-19. It combines barcoded multi-target amplification, 15-minute barcoded library preparation and real-time...
Lying in wait: the resurgence of dengue virus after the Zika epidemic in Brazil
After Zika virus (ZIKV) emerged and caused an epidemic in the Americas in 2016, both Zika and dengue incidence declined in the following years (2017-2018) to a record low in many countries. Following this period of low incidence, dengue resurged in...
Controlling Human Rabies: The Development of an Effective, Inexpensive and Locally Made Passive Cooling Device for Storing Thermotolerant Animal Rabies Vaccines
Thermotolerant vaccines greatly improved the reach and impact of large-scale vaccination programs to eliminate diseases such as smallpox, polio and rinderpest. A recent study demonstrated that the potency of the Nobivac® Canine Rabies vaccine was...
Fatal outcome of chikungunya virus infection in Brazil
AbstractBackground. Chikungunya virus (CHIKV) emerged in the Americas in 2013 and has caused ~2.1 million cases and over 600 deaths. A retrospective investigat