Mark BallAUA #uromatch2019 data interesting: on avg, applicants applied to 71 programs, w 37 interviews for 330 spots. 38% applications matched at 1st choice, but 68% of programs matched 5th choice of lower. @AmerUrological
To describe a family in which three members presented with mixed epithelial tumor
of the kidney (MEST) and were found to possess a germline mutation in CDC73, a gene
which is associated with hyperparathyroidism-jaw tumor syndrome (HPT-JT).
Large-scale loss-of-function screens and TP53 saturation mutagenesis screens in human cancer cell lines suggest that mutational processes combine with phenotypic selection to shape the landscape of somatic mutations at the TP53 locus.
The optimal sequence of cytoreductive nephrectomy and targeted therapy of metastatic
renal cell carcinoma is unclear. We compared overall survival between patients with
metastatic renal cell carcinoma treated with initial cytoreductive nephrectomy...
This review approaches cancer treatment as a game theoretic contest between the physician’s therapy and the cancer cells’ resistance strategies and suggests how treatment strategies can be improved by exploiting the critical asymmetries between the...
Many clear cell renal cell carcinomas (ccRCCs) have alterations to the gene encoding the von Hippel-Lindau protein (VHL). VHL is a ubiquitin ligase that degrades target proteins when they are prolyl-hydroxylated. Zhang et al. performed a genome-wide...