DS-I Africa Virtual Symposium Platform Welcome In coordination with the launch of the NIH Common Fund’s Harnessing Data Science for Health Discovery and Innovation in Africa (DS-I Africa) program, NIH is hosting an online-only, Virtual Symposium...
George Mensah, MDAt @NIH_NHLBI, we are proud of the outstanding work of SPRINT Investigators. They’ve just published another compelling #RCT that shows that lowering BP to less than 120 mmHg reduces incident #Afib by more 26% compared to lowering BP to less than 140. @NIH
George Mensah, MD.#ADAPTABLE trial investigators publish overview of the development & implementation of a computable #phenotype as an efficient method to recruit patients in large-scale multi-isite pragmatic #ClinicalTrials. @PCORI #aspirin #ImpSci #ASCVD #CVD #EHR #costs bit.ly/3gwtFxnpic.twitter.com/0jkMK2M7Ju
George Mensah, MDCompared to #aspirin monotherapy, the combination of rivaroxaban + aspirin prevented more #stroke & #cardiovascular events; and severe #bleeding was less frequent. Net clinical #benefit was particularly favorable in high-risk subgroups. #COMPASS Trial.
This cohort study, conducted from January 20, 2020, to February 10, 2020, in Wuhan, China, explores the prevalence of cardiac injury in hospitalized patients with COVID-19 and its association with mortality.
George Mensah, MDNew #JAMA. Cardiac injury is a common condition in patients hospitalized with COVID-19, and it is associated with a higher risk of in-hospital #mortality. Exact mechanism needs to be further explored. #Wuhan #COVID19 care. ja.ma/2Uw7nS8 #COVID #Coronavirus #Virus pic.twitter.com/WiJszoUs2j
This single-center case series describes the demographics, symptoms, laboratory and imaging findings, treatment, and clinical course of 138 patients hospitalized with 2019 novel coronavirus (2019-nCoV)–infected pneumonia (NCIP) in Wuhan, China,...
George Mensah, MDCOVID-19 is a multi-system disease. #JAMA: During hospitalization in #China, non-survivors had more severe lymphopenia over time; higher WBC & neutrophil counts; and higher D-dimer. Levels of #BUN & #creatinine progressively increased before death. ja.ma/2WzJI5Kpic.twitter.com/oAXmf54azu
Atrial fibrillation (AF) is the most common clinical arrhythmia and one of the major causes of stroke, heart failure, sudden death, and cardiovascular morbidity. Despite substantial advan...
George Mensah, MDFemale sex is an established #Risk Factor for #stroke in atrial #fibrillation. However, in practice, women appear less likely to receive specialist care and when they do, a more conservative approach is often followed. Sex-specific mechanisms. #Women #AFib bit.ly/2VlamyWpic.twitter.com/FgyhN2gDwK
A step-wedged cluster randomized trial, carried out in six villages in Tumbes, Peru, with 2,376 participants, demonstrates population-wide reductions in blood pressure, which appear to be higher in individuals with hypertension, as well as...
In response to the 1990s HIV/AIDS pandemic ravaging sub-Saharan Africa, global research
funders expanded portfolios in the region and massively increased HIV/AIDS research
investments. This support has grown substantially over time but with little...
George Mensah, MDSignificant sex differences in #HeartFailure with preserved EF: Despite worse symptoms, more #congestion, and lower #quality of life, women had similar #hospitalization rates and better survival than men. Their risk of sudden death was half that of men. bit.ly/2FnFEMipic.twitter.com/kjy8TDlJPu
This Viewpoint discusses the challenges and successes of the application of microbiome science to human health and highlights the need for basic mechanistic research informed by clinical questions to advance the field.
ent and action in the global HIV response.
We review challenges for economic evaluation relevant to the global HIV response and consider how the practice of cost-effectiveness analysis could integrate approaches and insights from...
This Viewpoint discusses the position of the National Institutes of Health (NIH) regarding disparities in health and research and offers recommendations that could hasten progress in eliminating disparities on the basis of race/ethnicity, sex, and...