Peter Openshaw
Mucosal immunologist and respiratory physician, working on lung infections (esp. RSV and influenza) at Imperial College London.
Last synced from Twitter 125d ago
The concept of “fatigue” in tackling covid-19 - The BMJ
Instead of using the concept of “fatigue” to understand patterns of adherence to rules for preventing the spread of covid-19, we should focus on—and address—specific aspects of people’s capability, opportunity, [...]More...
Today - 20/10/2020 - BBC Sounds
News and current affairs, including Sports Desk, Weather and Thought for the Day.
Human challenge studies with coronavirus: towards effective vaccines
HIC-Vac Human Challenge Studies - animation text.docx
Dozens to be deliberately infected with coronavirus in UK ‘human challenge’ trials
Proponents of the trials say they can be run safely and help to identify effective vaccines, but others have questioned their value.
Making a bed for viral infections
In the past 100 years, humans have harnessed the power of antibiotics to save countless lives from bacterial infection, however, our capacity to treat viral illnesses lags far behind. Prevention through vaccination has been the most effective method...
UK researchers to explore human challenge studies for COVID-19 | Imperial News | Imperial College London
Researchers are set to explore a human challenge study with the virus that causes COVID-19, the first such study anywhere in the world.
“Under the radar” - Ongoing Lassa Fever Outbreak - GIDEON - Global Infectious Diseases and Epidemiology Online Network
An ongoing outbreak of Lassa Fever continues in Nigeria well into 2020 – with 5,527 cases (222 fatal) reported as of August 16th.
What reinfections mean for COVID-19
One of the key questions in predicting the course of the COVID-19 pandemic, caused
by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is how well and how
long the immune responses protect the host from reinfection. For some viruses,...
Measles skin rash: infection of lymphoid and myeloid cells in the dermis precedes viral dissemination to the epidermis
Author summary Several viral infections are associated with skin rash, including parvovirus B19, human herpesvirus type 6, dengue virus and rubella virus. However, the archetype virus infection that leads to skin rash is measles. Although all of...
Age-dependent Interactions Among Clinical Characteristics,... : The Pediatric Infectious Disease Journal
nts) and severe (inpatients) RSV infection were enrolled and viral loads measured by polymerase chain reaction in nasopharyngeal swabs. Patients were stratified by age in 0–<3, 3–6 and >6–24 months, and multivariable analyses were performed to...
Coronavirus Pandemic Data Explorer
Research and data to make progress against the world’s largest problems
Remdesivir for the Treatment of Covid-19 — Preliminary Report | NEJM
Original Article from The New England Journal of Medicine — Remdesivir for the Treatment of Covid-19 — Preliminary Report
Neutrophilic inflammation in the respiratory mucosa predisposes to RSV infection
Why some individuals come down with a cold in any given year, whereas others are spared, is poorly understood. Habibi et al. exposed volunteers to respiratory syncytial virus (RSV), one of the pathogens responsible for the common cold, and then...
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Peter Openshaw
Neutrophilic inflammation in the respiratory mucosa predisposes to RSV infection. So glad to get this out 👍Nice Perspective in same issue.
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Bacteria-fighting cells in the airways boosts infection risk from viruses | Imperial News | Imperial College London
Having more bacteria-fighting immune cells in the nose and throat may explain why some people are more likely to be infected by respiratory viruses.
Face masks: what the data say
The science supports that face coverings save lives, and yet the debate trundles on. How much evidence is enough?
Dying in a Leadership Vacuum | NEJM
Editorial from The New England Journal of Medicine — Dying in a Leadership Vacuum
There is no ‘scientific divide’ over herd immunity
There’s a lot of talk of scientists divided over Covid-19, but when you look at the evidence any so-called divide starts to evaporate